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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 36

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Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion.
Dickerson MT, Dadi PK, Butterworth RB, Nakhe AY, Graff SM, Zaborska KE, Schaub CM, Jacobson DA
(2020) J Physiol 598: 4887-4905
MeSH Terms: Animals, Calcium, Calcium Channels, L-Type, Glucagon-Secreting Cells, Glucose, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Dapagliflozin Does Not Directly Affect Human α or β Cells.
Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC
(2020) Endocrinology 161:
MeSH Terms: Adolescent, Adult, Animals, Benzhydryl Compounds, Cells, Cultured, Female, Glucagon, Glucagon-Secreting Cells, Glucosides, Heterografts, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Mice, Inbred NOD, Mice, Transgenic, Middle Aged, Signal Transduction, Species Specificity, Young Adult
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health.
Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R
(2020) Diabetes 69: 342-354
MeSH Terms: Acinar Cells, Adolescent, Adult, Age Factors, Aged, Animals, Child, Child, Preschool, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Embryonic Stem Cells, Female, Glucagon-Secreting Cells, Humans, Infant, Insulin-Secreting Cells, Islets of Langerhans, Islets of Langerhans Transplantation, Lipid Droplets, Male, Mice, Microscopy, Electron, Microscopy, Fluorescence, Middle Aged, Rats, Tissue Donors, Young Adult
Added March 29, 2020
0 Communities
1 Members
0 Resources
27 MeSH Terms
Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.
Dickerson MT, Dadi PK, Altman MK, Verlage KR, Thorson AS, Jordan KL, Vierra NC, Amarnath G, Jacobson DA
(2019) Am J Physiol Endocrinol Metab 316: E646-E659
MeSH Terms: Alkanes, Animals, Apamin, Calcium, Calcium Channels, Calcium Channels, L-Type, Calcium Channels, P-Type, Calcium Channels, Q-Type, Endoplasmic Reticulum, Glucagon, Glucagon-Secreting Cells, Glucose, Mice, Mice, Transgenic, Patch-Clamp Techniques, Peptides, Potassium Channel Blockers, Potassium Channels, Calcium-Activated, Pyrazoles, Quinolinium Compounds
Added February 13, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells.
Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, Chera S, Herrera PL
(2018) Nat Cell Biol 20: 1267-1277
MeSH Terms: Animals, Cell Differentiation, Cell Plasticity, Cell Proliferation, Female, Glucagon-Secreting Cells, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Inbred C57BL, Mice, Knockout, Mice, SCID, Mice, Transgenic, Signal Transduction, Smoothened Receptor
Added November 6, 2018
2 Communities
2 Members
1 Resources
16 MeSH Terms
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC
(2018) Cell Rep 22: 2667-2676
MeSH Terms: Adolescent, Adult, Animals, Case-Control Studies, Cellular Reprogramming, Child, Diabetes Mellitus, Type 1, Female, Gene Expression Regulation, Glucagon, Glucagon-Secreting Cells, Humans, Insulin Secretion, Insulin-Secreting Cells, Male, Mice, Middle Aged, Phenotype, Tissue Donors, Transcription Factors, Young Adult
Added March 8, 2018
0 Communities
4 Members
0 Resources
21 MeSH Terms
Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean D, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E
(2017) J Clin Invest 127: 4379-4393
MeSH Terms: Animals, Glucagon, Glucagon-Secreting Cells, Hepatocyte Nuclear Factor 3-beta, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Knockout, Regulatory-Associated Protein of mTOR, Signal Transduction
Added September 21, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Gcg knockin mice as a tool for genetic manipulation in pancreatic alpha cells.
Shiota C, Prasadan K, Guo P, Fusco J, Xiao X, Gittes GK
(2017) Diabetologia 60: 2399-2408
MeSH Terms: Animals, Female, Glucagon, Glucagon-Like Peptide 1, Glucagon-Secreting Cells, Immunohistochemistry, Male, Mice, Mice, Transgenic, Proglucagon, Tamoxifen
Added August 13, 2019
0 Communities
0 Members
0 Resources
MeSH Terms
Glucagon antagonism in islet cell proliferation.
Dean ED, Unger RH, Holland WL
(2017) Proc Natl Acad Sci U S A 114: 3006-3008
MeSH Terms: Cell Proliferation, Glucagon, Glucagon-Secreting Cells, Humans, Insulin, Islets of Langerhans
Added September 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.
Petrenko V, Saini C, Giovannoni L, Gobet C, Sage D, Unser M, Heddad Masson M, Gu G, Bosco D, Gachon F, Philippe J, Dibner C
(2017) Genes Dev 31: 383-398
MeSH Terms: Animals, Cells, Cultured, Circadian Clocks, Colforsin, Enzyme Activators, Gene Expression Profiling, Gene Expression Regulation, Glucagon, Glucagon-Secreting Cells, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Models, Animal, Sequence Analysis, RNA, Time Factors
Added December 4, 2020
1 Communities
1 Members
0 Resources
MeSH Terms