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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 35

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Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer.
Short SP, Pilat JM, Barrett CW, Reddy VK, Haberman Y, Hendren JR, Marsh BJ, Keating CE, Motley AK, Hill KE, Zemper AE, Washington MK, Shi C, Chen X, Wilson KT, Hyams JS, Denson LA, Burk RF, Rosen MJ, Williams CS
(2021) Gastroenterology 160: 1694-1708.e3
MeSH Terms: Adolescent, Animals, Azoxymethane, Case-Control Studies, Cell Transformation, Neoplastic, Child, Child, Preschool, Colitis, Colitis, Ulcerative, Colitis-Associated Neoplasms, Colon, DNA Damage, Dextran Sulfate, Disease Models, Animal, Female, Genomic Instability, Humans, Intestinal Mucosa, Liver, Male, Mice, Knockout, Myeloid Cells, Oxidative Stress, Selenoprotein P
Added March 11, 2021
0 Communities
2 Members
0 Resources
24 MeSH Terms
Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.
Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK
(2018) Cancer Res 78: 3135-3146
MeSH Terms: Animals, Carcinogenesis, Carcinoma, Renal Cell, Cell Line, Tumor, Chromosomes, Human, Pair 3, Fibroblasts, Gene Knockdown Techniques, Genomic Instability, Haploinsufficiency, Histone-Lysine N-Methyltransferase, Histones, Humans, Kidney Neoplasms, Kidney Tubules, Proximal, Lysine, Methylation, Mice, Micronuclei, Chromosome-Defective, Microtubules
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
Dungrawala H, Bhat KP, Le Meur R, Chazin WJ, Ding X, Sharan SK, Wessel SR, Sathe AA, Zhao R, Cortez D
(2017) Mol Cell 67: 374-386.e5
MeSH Terms: A549 Cells, Animals, BRCA2 Protein, CRISPR-Cas Systems, DNA Breaks, Double-Stranded, DNA Repair, DNA, Neoplasm, Dose-Response Relationship, Drug, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Genomic Instability, HEK293 Cells, Humans, Mice, Models, Molecular, Mutation, Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, Protein Binding, RNA Interference, Rad51 Recombinase, Replication Origin, Transfection
Added March 24, 2018
0 Communities
1 Members
0 Resources
23 MeSH Terms
Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability.
Wanzek K, Schwindt E, Capra JA, Paeschke K
(2017) Nucleic Acids Res 45: 7796-7806
MeSH Terms: Binding Sites, Cell Cycle, Cullin Proteins, DNA Helicases, DNA Replication, DNA, Fungal, Endodeoxyribonucleases, Exodeoxyribonucleases, G-Quadruplexes, GC Rich Sequence, Genomic Instability, Models, Biological, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Added March 14, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
ETAA1 acts at stalled replication forks to maintain genome integrity.
Bass TE, Luzwick JW, Kavanaugh G, Carroll C, Dungrawala H, Glick GG, Feldkamp MD, Putney R, Chazin WJ, Cortez D
(2016) Nat Cell Biol 18: 1185-1195
MeSH Terms: Adaptor Proteins, Signal Transducing, Antigens, Surface, Ataxia Telangiectasia Mutated Proteins, Carrier Proteins, Cell Cycle Proteins, Cell Line, DNA Damage, DNA Replication, DNA-Binding Proteins, Genome, Human, Genomic Instability, Humans, Protein-Serine-Threonine Kinases, Proteomics, Signal Transduction
Added April 18, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, Cristea IM, Zakian VA, Capra JA, Sabouri N
(2016) PLoS Genet 12: e1006238
MeSH Terms: Binding Sites, DNA Helicases, DNA Replication, DNA-Directed DNA Polymerase, Genomic Instability, Multienzyme Complexes, Protein Binding, S Phase, Schizosaccharomyces, Schizosaccharomyces pombe Proteins
Added April 18, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL
(2016) Cell 166: 950-962
MeSH Terms: Cell Line, Tumor, Chromatin Assembly and Disassembly, Cytokinesis, Cytoskeleton, Genomic Instability, Histone Code, Histone-Lysine N-Methyltransferase, Histones, Humans, Lysine, Methylation, Microtubules, Mitosis, Protein Processing, Post-Translational, Tubulin
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells.
Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB
(2016) PLoS One 11: e0150372
MeSH Terms: Adult, Aged, Cells, Cultured, DNA Damage, Gene Knockdown Techniques, Genomic Instability, Humans, Huntington Disease, Induced Pluripotent Stem Cells, Karyotyping, Middle Aged, Nucleic Acid Synthesis Inhibitors, Signal Transduction, Tumor Suppressor Protein p53, Young Adult, Zinostatin
Added August 18, 2016
0 Communities
2 Members
0 Resources
16 MeSH Terms
A whole genome RNAi screen identifies replication stress response genes.
Kavanaugh G, Ye F, Mohni KN, Luzwick JW, Glick G, Cortez D
(2015) DNA Repair (Amst) 35: 55-62
MeSH Terms: Cell Line, Tumor, Checkpoint Kinase 1, DNA Damage, DNA Repair, DNA Replication, DNA, Single-Stranded, Genome, Human, Genomic Instability, Genomics, Humans, Microscopy, Fluorescence, Protein Kinases, RNA Interference, RNA, Small Interfering
Added February 4, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage.
Barrett CW, Reddy VK, Short SP, Motley AK, Lintel MK, Bradley AM, Freeman T, Vallance J, Ning W, Parang B, Poindexter SV, Fingleton B, Chen X, Washington MK, Wilson KT, Shroyer NF, Hill KE, Burk RF, Williams CS
(2015) J Clin Invest 125: 2646-60
MeSH Terms: Animals, Antioxidants, Apoptosis, Colitis, Colonic Neoplasms, DNA Damage, Genomic Instability, Haploinsufficiency, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, Mutagenesis, Site-Directed, Neoplastic Stem Cells, Oxidative Stress, Protein Structure, Tertiary, Selenium, Selenoprotein P, Tumor Microenvironment, Tumor Suppressor Proteins
Added July 10, 2015
0 Communities
6 Members
0 Resources
20 MeSH Terms