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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

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Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis.
Dumitru R, Gama V, Fagan BM, Bower JJ, Swahari V, Pevny LH, Deshmukh M
(2012) Mol Cell 46: 573-83
MeSH Terms: Acetylation, Antigens, Nuclear, Apoptosis, Biological Transport, DNA Damage, DNA-Binding Proteins, Embryonic Stem Cells, Gene Silencing, Genes, bcl-2, Golgi Apparatus, Humans, Ku Autoantigen, Mitochondria, Tumor Suppressor Protein p53, bcl-2-Associated X Protein
Added October 26, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway.
Thu YM, Su Y, Yang J, Splittgerber R, Na S, Boyd A, Mosse C, Simons C, Richmond A
(2012) Oncogene 31: 2580-92
MeSH Terms: Animals, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cell Survival, Cyclin D2, Down-Regulation, Enzyme Activation, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Genes, bcl-2, Genes, myc, Humans, Melanoma, Melanoma, Experimental, Mice, Neoplasm Metastasis, Protein Serine-Threonine Kinases, RNA, Small Interfering, Signal Transduction, beta Catenin
Added June 14, 2013
2 Communities
2 Members
0 Resources
21 MeSH Terms
t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism.
Belkhiri A, Dar AA, Zaika A, Kelley M, El-Rifai W
(2008) Cancer Res 68: 395-403
MeSH Terms: Activating Transcription Factor 1, Carcinoma, Caspase 3, Caspase 9, Cell Survival, Cyclic AMP Response Element-Binding Protein, Cytochromes c, DNA-Binding Proteins, Dopamine and cAMP-Regulated Phosphoprotein 32, Gene Expression Regulation, Neoplastic, Genes, bcl-2, Humans, Membrane Potential, Mitochondrial, Nuclear Proteins, Oncogene Protein v-akt, Phosphorylation, Protein Isoforms, RNA, Messenger, Regulatory Factor X Transcription Factors, Signal Transduction, Stomach Neoplasms, Transcription Factors, Tumor Cells, Cultured, Up-Regulation
Added March 5, 2014
0 Communities
2 Members
0 Resources
24 MeSH Terms
Pleiotropic role of VEGF-A in regulating fetal pulmonary mesenchymal cell turnover.
Majka S, Fox K, McGuire B, Crossno J, McGuire P, Izzo A
(2006) Am J Physiol Lung Cell Mol Physiol 290: L1183-92
MeSH Terms: Animals, Base Sequence, Cell Cycle, Cell Division, DNA Primers, Fetus, Genes, bcl-2, Immunohistochemistry, Lung, Mesoderm, Mice, Mice, Knockout, Organ Culture Techniques, Proto-Oncogene Proteins p21(ras), Vascular Endothelial Growth Factor A
Added August 4, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
Eischen CM, Packham G, Nip J, Fee BE, Hiebert SW, Zambetti GP, Cleveland JL
(2001) Oncogene 20: 6983-93
MeSH Terms: Animals, Apoptosis, Cell Cycle Proteins, Cell Line, Transformed, Cell Transformation, Neoplastic, DNA, DNA-Binding Proteins, E2F Transcription Factors, E2F1 Transcription Factor, Gene Expression Regulation, Genes, bcl-2, Genes, myc, Genes, p53, Interleukin-3, Mice, Mutation, Myeloid Cells, Protein Binding, Protein Conformation, Proto-Oncogene Proteins c-bcl-2, Proto-Oncogene Proteins c-myc, Recombinant Fusion Proteins, Temperature, Transcription Factors, Transfection, Tumor Suppressor Protein p14ARF, Tumor Suppressor Protein p53, bcl-X Protein
Added June 10, 2010
1 Communities
2 Members
0 Resources
28 MeSH Terms
4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.
Ji C, Amarnath V, Pietenpol JA, Marnett LJ
(2001) Chem Res Toxicol 14: 1090-6
MeSH Terms: Aldehydes, Apoptosis, Caspase 3, Caspases, Colorectal Neoplasms, Cross-Linking Reagents, Cytochrome c Group, DNA Damage, Enzyme Induction, Gene Expression Regulation, Neoplastic, Genes, bcl-2, Humans, Lipid Peroxidation, Mitochondria, Proto-Oncogene Proteins c-bcl-2, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
IL-4-dependent induction of BCL-2 and BCL-X(L)IN activated T lymphocytes through a STAT6- and pi 3-kinase-independent pathway.
Aronica MA, Goenka S, Boothby M
(2000) Cytokine 12: 578-87
MeSH Terms: Androstadienes, Animals, Cell Division, Cell Line, Cell Survival, Crosses, Genetic, Enzyme Inhibitors, Genes, bcl-2, Interleukin-4, Lymphocyte Activation, Mice, Mice, Knockout, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-bcl-2, Receptors, Interleukin-4, Recombinant Proteins, STAT6 Transcription Factor, Signal Transduction, Sirolimus, T-Lymphocytes, Cytotoxic, Trans-Activators, Transcriptional Activation, Transfection, Wortmannin, bcl-X Protein
Added December 10, 2013
0 Communities
1 Members
0 Resources
25 MeSH Terms