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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy.
Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM
(2016) Nat Commun 7: 10582
MeSH Terms: Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Genes, MHC Class II, Genotype, Humans, Melanoma, Nivolumab, Programmed Cell Death 1 Receptor, RNA, Messenger
Added January 30, 2016
4 Communities
7 Members
0 Resources
11 MeSH Terms
Mapping the genetic architecture of gene expression in human liver.
Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R
(2008) PLoS Biol 6: e107
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Animals, Child, Child, Preschool, Cholesterol, LDL, Coronary Artery Disease, Diabetes Mellitus, Type 1, Female, Gene Expression Profiling, Genes, MHC Class II, Genetic Predisposition to Disease, Genome, Human, Genotype, Humans, Infant, Liver, Male, Mice, Middle Aged, Oligonucleotide Array Sequence Analysis, Polymorphism, Single Nucleotide, Quantitative Trait Loci, RNA, Messenger, Transcription, Genetic
Added March 26, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation.
Das J, Eynott P, Jupp R, Bothwell A, Van Kaer L, Shi Y, Das G
(2006) Nat Med 12: 1345-6; author reply 1347
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Genes, MHC Class II, Inflammation, Killer Cells, Natural, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Respiratory Hypersensitivity, Respiratory Tract Diseases, T-Lymphocytes
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.
Gialitakis M, Kretsovali A, Spilianakis C, Kravariti L, Mages J, Hoffmann R, Hatzopoulos AK, Papamatheakis J
(2006) Nucleic Acids Res 34: 765-72
MeSH Terms: Acetylation, Antineoplastic Agents, Cell Line, Tumor, Chromatin Immunoprecipitation, DNA-Binding Proteins, Enhancer Elements, Genetic, Enzyme Inhibitors, Gene Expression Profiling, Genes, MHC Class II, HLA-DR Antigens, HLA-DR alpha-Chains, HeLa Cells, Histone Deacetylase Inhibitors, Histones, Humans, Hydroxamic Acids, Regulatory Factor X Transcription Factors, Transcription Factors, Transcriptional Activation
Added November 18, 2010
1 Communities
1 Members
0 Resources
19 MeSH Terms
Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents.
Tang J, Wilson CM, Meleth S, Myracle A, Lobashevsky E, Mulligan MJ, Douglas SD, Korber B, Vermund SH, Kaslow RA, REACH Study Group. Reaching for Excellence in Adolescent Care and Health
(2002) AIDS 16: 2275-84
MeSH Terms: Adolescent, Algorithms, Alleles, CD4 Lymphocyte Count, Female, Follow-Up Studies, Genes, MHC Class II, Genetic Markers, Genetic Predisposition to Disease, HIV Infections, HIV-1, Haplotypes, Histocompatibility Testing, Humans, Male, Prognosis, Receptors, CCR2, Receptors, Chemokine, Viral Load, Viremia
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
MHC class II alpha/beta heterodimeric cell surface molecules expressed from a single proviral genome.
Shimada H, Germana S, Sonntag KC, Banerjee P, Moore D, Sachs DH, LeGuern C
(1999) Hum Gene Ther 10: 2397-405
MeSH Terms: 3T3 Cells, Animals, Blotting, Northern, Blotting, Southern, Flow Cytometry, Gene Expression, Gene Transfer Techniques, Genes, MHC Class II, Genetic Vectors, HLA-DQ Antigens, Mice, Proviruses, Retroviridae, Reverse Transcriptase Polymerase Chain Reaction, Swine
Added October 24, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Distinct IL-4 response mechanisms of the MHC gene A alpha in different mouse B cell lines.
Whitley MZ, Cheng HL, Tomasi TB, Boothby M
(1993) Mol Immunol 30: 821-32
MeSH Terms: Animals, B-Lymphocytes, Gene Expression Regulation, Genes, MHC Class II, Histocompatibility Antigens Class II, Interleukin-4, Mice, RNA, Messenger, Transcription, Genetic, Tumor Cells, Cultured
Added December 10, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Amino acid substitutions in the floor of the putative antigen-binding site of H-2T22 affect recognition by a gamma delta T-cell receptor.
Moriwaki S, Korn BS, Ichikawa Y, van Kaer L, Tonegawa S
(1993) Proc Natl Acad Sci U S A 90: 11396-400
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Biological Transport, Carrier Proteins, Genes, MHC Class II, H-2 Antigens, Histocompatibility Antigens Class II, Lymphocyte Activation, Mice, Mutagenesis, Site-Directed, Protein Binding, Protein Structure, Tertiary, Receptors, Antigen, T-Cell, gamma-delta, Recombinant Proteins, Structure-Activity Relationship, Transfection
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Altered peptidase and viral-specific T cell response in LMP2 mutant mice.
Van Kaer L, Ashton-Rickardt PG, Eichelberger M, Gaczynska M, Nagashima K, Rock KL, Goldberg AL, Doherty PC, Tonegawa S
(1994) Immunity 1: 533-41
MeSH Terms: Animals, Antigen Presentation, Antigen-Presenting Cells, Antigens, Viral, CD8-Positive T-Lymphocytes, Cysteine Endopeptidases, Genes, MHC Class II, Histocompatibility Antigens Class I, Liver, Mice, Mice, Knockout, Orthomyxoviridae, Parainfluenza Virus 1, Human, Peptide Hydrolases, Proteins, Spleen, T-Lymphocyte Subsets, T-Lymphocytes, T-Lymphocytes, Cytotoxic
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3).
Quaranta V, Majdic O, Stingl G, Liszka K, Honigsmann H, Knapp W
(1984) J Immunol 132: 1900-5
MeSH Terms: Animals, Antibodies, Monoclonal, B-Lymphocytes, Cytoplasm, Electrophoresis, Polyacrylamide Gel, Epitopes, Fluorescent Antibody Technique, Genes, MHC Class II, Histocompatibility Antigens Class II, Humans, Mice, Mice, Inbred BALB C, Polymorphism, Genetic, Rabbits
Added March 27, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms