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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 5 of 5

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Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration.
Haas DW, Bartlett JA, Andersen JW, Sanne I, Wilkinson GR, Hinkle J, Rousseau F, Ingram CD, Shaw A, Lederman MM, Kim RB, Adult AIDS Clinical Trials Group
(2006) Clin Infect Dis 43: 783-6
MeSH Terms: Adult, Anti-HIV Agents, Aryl Hydrocarbon Hydroxylases, Case-Control Studies, Chemical and Drug Induced Liver Injury, Cytochrome P-450 CYP2B6, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Female, Gene Frequency, Genes, MDR, Genotype, HIV Infections, HIV-1, Humans, Liver, Liver Diseases, Male, Nevirapine, Oxidoreductases, N-Demethylating, Polymorphism, Genetic, Randomized Controlled Trials as Topic, Reverse Transcriptase Inhibitors, South Africa
Added March 13, 2015
0 Communities
1 Members
0 Resources
24 MeSH Terms
Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity.
Ritchie MD, Haas DW, Motsinger AA, Donahue JP, Erdem H, Raffanti S, Rebeiro P, George AL, Kim RB, Haines JL, Sterling TR
(2006) Clin Infect Dis 43: 779-82
MeSH Terms: Adult, Alkynes, Anti-HIV Agents, Aryl Hydrocarbon Hydroxylases, Benzoxazines, Case-Control Studies, Chemical and Drug Induced Liver Injury, Cyclopropanes, Cytochrome P-450 CYP2B6, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Female, Genes, MDR, Genetic Variation, Genotype, HIV Infections, HIV-1, Humans, Liver, Liver Diseases, Male, Nevirapine, Oxazines, Oxidoreductases, N-Demethylating, Reverse Transcriptase Inhibitors
Added March 13, 2015
0 Communities
1 Members
0 Resources
25 MeSH Terms
MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.
Haas DW, Wu H, Li H, Bosch RJ, Lederman MM, Kuritzkes D, Landay A, Connick E, Benson C, Wilkinson GR, Kessler H, Kim RB
(2003) J Acquir Immune Defic Syndr 34: 295-8
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Alleles, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, Drug Therapy, Combination, Female, Genes, MDR, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Lamivudine, Male, Middle Aged, Polymorphism, Single Nucleotide, RNA, Viral, Retrospective Studies, Ritonavir, Zidovudine
Added March 13, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Identification of functionally variant MDR1 alleles among European Americans and African Americans.
Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, Taylor A, Xie HG, McKinsey J, Zhou S, Lan LB, Schuetz JD, Schuetz EG, Wilkinson GR
(2001) Clin Pharmacol Ther 70: 189-99
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Africa, Alleles, Anti-Allergic Agents, Area Under Curve, Blacks, Cloning, Molecular, DNA Primers, Digoxin, Enzyme Inhibitors, Europe, Genes, MDR, Genetic Variation, Genotype, Haplotypes, Humans, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Sequence Analysis, DNA, Terfenadine, Time Factors, Whites
Added March 27, 2014
1 Communities
1 Members
2 Resources
22 MeSH Terms
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.
Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB
(1999) Drug Metab Dispos 27: 866-71
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Anion Transport Proteins, Biological Transport, Active, Caco-2 Cells, Carrier Proteins, Genes, MDR, HeLa Cells, Histamine H1 Antagonists, Humans, LLC-PK1 Cells, Mice, Rats, Swine, Terfenadine, Tissue Distribution, Transfection, Vaccinia virus
Added March 27, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms