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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 115

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Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.
Mosleh E, Ou K, Haemmerle MW, Tembo T, Yuhas A, Carboneau BA, Townsend SE, Bosma KJ, Gannon M, O'Brien RM, Stoffers DA, Golson ML
(2020) Endocrinology 161:
MeSH Terms: Alleles, Animals, Cells, Cultured, DNA Methylation, Female, Gene Silencing, HEK293 Cells, Humans, Insulin, Insulin-Secreting Cells, Integrases, Islets of Langerhans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Organ Specificity, Recombination, Genetic
Added May 12, 2020
1 Communities
0 Members
0 Resources
18 MeSH Terms
Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway.
Gobert AP, Latour YL, Asim M, Finley JL, Verriere TG, Barry DP, Milne GL, Luis PB, Schneider C, Rivera ES, Lindsey-Rose K, Schey KL, Delgado AG, Sierra JC, Piazuelo MB, Wilson KT
(2019) mBio 10:
MeSH Terms: Animals, Bacteria, Gene Silencing, Helicobacter pylori, Histones, Humans, Immune Evasion, Immunity, Innate, Immunoglobulins, Macrophages, Male, Metabolic Networks and Pathways, Mice, Mice, Inbred C57BL, Nitric Oxide Synthase Type II, Phosphatidylinositol 3-Kinases, Polyamines, RAW 264.7 Cells, Spermidine, Spermine, Sulfur, Transcription Factors
Added November 1, 2019
0 Communities
2 Members
0 Resources
22 MeSH Terms
Loss of MYO5B Leads to Reductions in Na Absorption With Maintenance of CFTR-Dependent Cl Secretion in Enterocytes.
Engevik AC, Kaji I, Engevik MA, Meyer AR, Weis VG, Goldstein A, Hess MW, Müller T, Koepsell H, Dudeja PK, Tyska M, Huber LA, Shub MD, Ameen N, Goldenring JR
(2018) Gastroenterology 155: 1883-1897.e10
MeSH Terms: Animals, Aquaporins, Chlorides, Cystic Fibrosis Transmembrane Conductance Regulator, Duodenum, Enterocytes, Gene Silencing, Humans, Intestinal Mucosa, Intestines, Malabsorption Syndromes, Mice, Mice, Knockout, Microvilli, Mucolipidoses, Myosin Type V, Protein Transport, Sodium-Glucose Transporter 1, Sodium-Hydrogen Exchanger 3, Sodium-Hydrogen Exchangers, Sucrase-Isomaltase Complex, Tamoxifen
Added February 7, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
Nanotechnology Enabled Modulation of Signaling Pathways Affects Physiologic Responses in Intact Vascular Tissue.
Hocking KM, Evans BC, Komalavilas P, Cheung-Flynn J, Duvall CL, Brophy CM
(2019) Tissue Eng Part A 25: 416-426
MeSH Terms: Actin Cytoskeleton, Actins, Animals, Blood Vessels, Calcium, Gene Silencing, Heat-Shock Proteins, Humans, Micelles, Muscle Contraction, Muscle, Smooth, Nanoparticles, Nanotechnology, Peptides, Polymerization, RNA, Small Interfering, Rats, Signal Transduction, Static Electricity
Added April 10, 2019
0 Communities
2 Members
0 Resources
19 MeSH Terms
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.
Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Cancer Genome Atlas Research Network, Monnat RJ, Xiao Y, Wang C
(2018) Cell Rep 23: 239-254.e6
MeSH Terms: Cell Line, Tumor, DNA Damage, Gene Silencing, Genome, Human, Humans, Loss of Heterozygosity, Machine Learning, Mutation, Neoplasms, Recombinational DNA Repair, Tumor Suppressor Proteins
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.
Sarett SM, Werfel TA, Lee L, Jackson MA, Kilchrist KV, Brantley-Sieders D, Duvall CL
(2017) Proc Natl Acad Sci U S A 114: E6490-E6497
MeSH Terms: Cell Line, Tumor, Gene Silencing, Humans, Neoplasms, RNA, Small Interfering, Serum Albumin, Human
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.
Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M
(2017) Nat Commun 8: 93
MeSH Terms: Adipocytes, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Cell Line, Diet, High-Fat, Gene Expression Regulation, Gene Silencing, Histone Deacetylases, Lipid Metabolism, Male, Mice, Mice, Knockout
Added February 7, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
Blocking Zebrafish MicroRNAs with Morpholinos.
Flynt AS, Rao M, Patton JG
(2017) Methods Mol Biol 1565: 59-78
MeSH Terms: Animals, Electroporation, Gene Expression Regulation, Gene Silencing, Gene Transfer Techniques, MicroRNAs, Microinjections, Morpholinos, Oligonucleotides, Antisense, Retina, Zebrafish
Added August 4, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms
Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer.
Ludwik KA, Campbell JP, Li M, Li Y, Sandusky ZM, Pasic L, Sowder ME, Brenin DR, Pietenpol JA, O'Doherty GA, Lannigan DA
(2016) Mol Cancer Ther 15: 2598-2608
MeSH Terms: Animals, Antineoplastic Agents, Benzopyrans, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Disease Models, Animal, Dose-Response Relationship, Drug, Enzyme Activation, Female, Gene Silencing, Humans, Mice, Monosaccharides, Neoplasm Metastasis, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Ribosomal Protein S6 Kinases, 90-kDa, Triple Negative Breast Neoplasms, Tumor Burden, Xenograft Model Antitumor Assays
Added September 14, 2016
1 Communities
3 Members
0 Resources
22 MeSH Terms
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.
Sarett SM, Werfel TA, Chandra I, Jackson MA, Kavanaugh TE, Hattaway ME, Giorgio TD, Duvall CL
(2016) Biomaterials 97: 122-32
MeSH Terms: Animals, Cell Line, Tumor, Drug Carriers, Female, Gene Silencing, Humans, Hydrophobic and Hydrophilic Interactions, Mice, Nude, Neoplasms, Palmitic Acid, Polyethylene Glycols, Polymers, RNA, Small Interfering, Reproducibility of Results, Tissue Distribution
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms