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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.
Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR
(2017) Sci Adv 3: eaao4774
MeSH Terms: Bacteriophage mu, Base Pairing, Cell Line, DNA Repair, DNA-Binding Proteins, Enzyme Activation, Gene Frequency, Gene Order, Humans, INDEL Mutation, Uracil-DNA Glycosidase, Viral Proteins
Added March 21, 2018
0 Communities
0 Members
1 Resources
12 MeSH Terms
Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs.
Yin L, Maddison LA, Li M, Kara N, LaFave MC, Varshney GK, Burgess SM, Patton JG, Chen W
(2015) Genetics 200: 431-41
MeSH Terms: Animals, Animals, Genetically Modified, CRISPR-Cas Systems, Gene Expression, Gene Order, Gene Silencing, Gene Targeting, Genetic Vectors, Glucose, Hypopigmentation, Mutagenesis, Phenotype, RNA, Guide, Transgenes, Zebrafish
Added July 23, 2015
0 Communities
2 Members
0 Resources
15 MeSH Terms
From hypothesis to mechanism: uncovering nuclear pore complex links to gene expression.
Burns LT, Wente SR
(2014) Mol Cell Biol 34: 2114-20
MeSH Terms: Animals, Gene Expression Regulation, Gene Order, Humans, Models, Biological, Nuclear Pore, Nuclear Pore Complex Proteins, RNA Transport
Added March 21, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Targeting piggyBac transposon integrations in the human genome.
Galvan DL, Kettlun CS, Wilson MH
(2014) Methods Mol Biol 1114: 143-61
MeSH Terms: DNA Transposable Elements, Gene Order, Gene Targeting, Genetic Vectors, Genome, Human, HEK293 Cells, Homologous Recombination, Humans, Mutagenesis, Insertional
Added March 6, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling.
Sethman CR, Hawiger J
(2013) PLoS One 8: e70994
MeSH Terms: Apoptosis, Armadillo Domain Proteins, Caspase 6, Cell Line, Cell Nucleus, Cytoskeletal Proteins, DNA Fragmentation, Gene Expression, Gene Order, Genetic Vectors, Humans, Immunity, Innate, Lamins, Protein Stability, Protein Transport, Signal Transduction, Tumor Necrosis Factor-alpha
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain.
Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P
(2013) Hum Mutat 34: 801-11
MeSH Terms: Amino Acid Sequence, Chromosome Mapping, Databases, Genetic, Female, Forkhead Transcription Factors, Gene Dosage, Gene Order, Humans, Infant, Infant, Newborn, Male, Molecular Sequence Data, Mutation, Open Reading Frames, Persistent Fetal Circulation Syndrome, Protein Interaction Domains and Motifs, Sequence Alignment
Added January 20, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element.
Collins PL, Henderson MA, Aune TM
(2012) Genes Immun 13: 481-8
MeSH Terms: Animals, Cell Lineage, Chromosomes, Artificial, Bacterial, Conserved Sequence, Enhancer Elements, Genetic, Evolution, Molecular, Gene Order, Histones, Humans, Interferon-gamma, Interleukins, Mice, Mice, Transgenic, Models, Genetic, Promoter Regions, Genetic, RNA Polymerase II, RNA, Untranslated, Sequence Deletion, Th1 Cells, Th17 Cells
Added December 10, 2013
1 Communities
1 Members
0 Resources
20 MeSH Terms
Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology.
Arnes L, Leclerc K, Friel JM, Hipkens SB, Magnuson MA, Sussel L
(2012) Genesis 50: 612-24
MeSH Terms: Animals, Central Nervous System, Gene Expression Regulation, Developmental, Gene Order, Gene Targeting, Genotype, Homeodomain Proteins, Homologous Recombination, Mice, Mice, Transgenic, Neural Stem Cells, Pancreas, Phenotype, Transcription Factors, Zebrafish Proteins, beta-Galactosidase
Added October 19, 2012
2 Communities
1 Members
1 Resources
16 MeSH Terms
Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity.
Stobart CC, Lee AS, Lu X, Denison MR
(2012) J Virol 86: 4801-10
MeSH Terms: Alleles, Amino Acid Sequence, Amino Acid Substitution, Animals, Coronavirus 3C Proteases, Cricetinae, Cysteine Endopeptidases, Enzyme Activation, Gene Order, Mice, Models, Molecular, Molecular Sequence Data, Murine hepatitis virus, Mutation, Phenotype, Protein Structure, Tertiary, Sequence Alignment, Temperature, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Evaluation of macrophage-specific promoters using lentiviral delivery in mice.
Levin MC, Lidberg U, Jirholt P, Adiels M, Wramstedt A, Gustafsson K, Greaves DR, Li S, Fazio S, Linton MF, Olofsson SO, Borén J, Gjertsson I
(2012) Gene Ther 19: 1041-7
MeSH Terms: Animals, Cell Line, Gene Dosage, Gene Expression, Gene Order, Genetic Therapy, Genetic Vectors, Green Fluorescent Proteins, Hematopoietic Stem Cell Transplantation, Hematopoietic Stem Cells, Humans, Lentivirus, Macrophages, Mice, Organ Specificity, Promoter Regions, Genetic, Transduction, Genetic, Transgenes
Added December 10, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms