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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 247

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In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate.
Fuller JC, Pitchford LM, Morrison RD, Daniels JS, Flynn CR, Abumrad NN, Oates JA, Boutaud O, Rathmacher JA
(2018) Food Chem Toxicol 121: 541-548
MeSH Terms: Adult, Benzylamines, Blood Proteins, Cytochrome P-450 Enzyme System, ERG1 Potassium Channel, Erythrocytes, Female, Gene Expression Regulation, Enzymologic, Hepatocytes, Humans, Male, Middle Aged, Mutagenicity Tests, Salmonella typhimurium
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE
(2018) Mol Cell 70: 936-948.e7
MeSH Terms: Binding Sites, Cell Death, Colonic Neoplasms, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, HT29 Cells, Herpesvirus 1, Human, Humans, Inositol Phosphates, Jurkat Cells, Mutation, Phosphorylation, Phosphotransferases (Alcohol Group Acceptor), Protein Kinases, Receptor-Interacting Protein Serine-Threonine Kinases, Signal Transduction, Tumor Necrosis Factor-alpha
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis.
Hudson BH, Hale AT, Irving RP, Li S, York JD
(2018) Proc Natl Acad Sci U S A 115: 3000-3005
MeSH Terms: Animals, Gene Expression Regulation, Enzymologic, Genotype, Homeostasis, Intestines, Iron, Mice, Mice, Knockout, Nucleotidases, Sulfur
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer.
Luo N, Nixon MJ, Gonzalez-Ericsson PI, Sanchez V, Opalenik SR, Li H, Zahnow CA, Nickels ML, Liu F, Tantawy MN, Sanders ME, Manning HC, Balko JM
(2018) Nat Commun 9: 248
MeSH Terms: Animals, Antineoplastic Agents, Azacitidine, Breast Neoplasms, Cell Line, Tumor, DNA (Cytosine-5-)-Methyltransferase 1, Female, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Genes, MHC Class I, Humans, Mammary Neoplasms, Experimental, Mice, Promoter Regions, Genetic, T-Lymphocytes, Cytotoxic
Added March 14, 2018
0 Communities
4 Members
0 Resources
15 MeSH Terms
Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.
Stark RJ, Koch SR, Choi H, Mace EH, Dikalov SI, Sherwood ER, Lamb FS
(2018) FASEB J 32: 945-956
MeSH Terms: Capillary Permeability, Cells, Cultured, Chronic Disease, Endothelial Cells, Gene Expression Regulation, Enzymologic, Humans, Imidazoles, Interleukin-6, Lipopolysaccharides, MAP Kinase Signaling System, Nitric Oxide, Nitric Oxide Synthase Type III, Pyridines, Toll-Like Receptor 4, Vasculitis, p38 Mitogen-Activated Protein Kinases
Added October 27, 2017
0 Communities
3 Members
0 Resources
16 MeSH Terms
The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism.
Bermingham DP, Hardaway JA, Refai O, Marks CR, Snider SL, Sturgeon SM, Spencer WC, Colbran RJ, Miller DM, Blakely RD
(2017) J Neurosci 37: 9288-9304
MeSH Terms: Animals, Animals, Genetically Modified, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cells, Cultured, Dopamine, Dopamine Plasma Membrane Transport Proteins, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Enzymologic, Neurons, rho-Associated Kinases
Added March 21, 2018
0 Communities
2 Members
0 Resources
11 MeSH Terms
Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis.
Feichtinger RG, Neureiter D, Skaria T, Wessler S, Cover TL, Mayr JA, Zimmermann FA, Posselt G, Sperl W, Kofler B
(2017) Oxid Med Cell Longev 2017: 1320241
MeSH Terms: Electron Transport Complex I, Female, Gastritis, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Helicobacter Infections, Helicobacter pylori, Humans, Male, Neoplasm Proteins, Oxidative Phosphorylation, Stomach Neoplasms
Added March 21, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Human mitochondrial cytochrome P450 27C1 is localized in skin and preferentially desaturates -retinol to 3,4-dehydroretinol.
Johnson KM, Phan TTN, Albertolle ME, Guengerich FP
(2017) J Biol Chem 292: 13672-13687
MeSH Terms: Biocatalysis, Cytochrome P450 Family 27, Diterpenes, Gene Expression Profiling, Gene Expression Regulation, Enzymologic, Humans, Hydrogenation, Hydroxylation, Isoenzymes, Kinetics, Mitochondria, Molecular Structure, Organ Specificity, Oxidation-Reduction, Peptide Fragments, Proteolysis, Proteomics, Skin, Stereoisomerism, Substrate Specificity, Vitamin A
Added March 14, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
Structure of a DNA glycosylase that unhooks interstrand cross-links.
Mullins EA, Warren GM, Bradley NP, Eichman BF
(2017) Proc Natl Acad Sci U S A 114: 4400-4405
MeSH Terms: Anti-Bacterial Agents, Bacterial Proteins, DNA Glycosylases, DNA, Bacterial, Gene Expression Regulation, Bacterial, Gene Expression Regulation, Enzymologic, Intercellular Signaling Peptides and Proteins, Models, Molecular, Mutation, Naphthalenes, Peptides, Protein Binding, Protein Conformation, Protein Folding, Streptomyces
Added August 26, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer.
Wilson AJ, Fadare O, Beeghly-Fadiel A, Son DS, Liu Q, Zhao S, Saskowski J, Uddin MJ, Daniel C, Crews B, Lehmann BD, Pietenpol JA, Crispens MA, Marnett LJ, Khabele D
(2015) Oncotarget 6: 21353-68
MeSH Terms: Carcinoma, Ovarian Epithelial, Cell Line, Tumor, Cell Movement, Cell Proliferation, Computational Biology, Cyclooxygenase 1, Female, Gene Expression Profiling, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Genome, Human, Humans, Immunohistochemistry, Neoplasm Invasiveness, Neoplasms, Glandular and Epithelial, Neovascularization, Pathologic, Oligonucleotide Array Sequence Analysis, Ovarian Neoplasms, Signal Transduction
Added July 28, 2015
1 Communities
6 Members
0 Resources
19 MeSH Terms