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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 555

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A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes.
Sun Y, Zhu J, Zhou D, Canchi S, Wu C, Cox NJ, Rissman RA, Gamazon ER, Wu L
(2021) Genome Med 13: 141
MeSH Terms: Alleles, Alzheimer Disease, Chromosome Mapping, Computational Biology, Databases, Genetic, Gene Expression Profiling, Gene Expression Regulation, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Models, Biological, Organ Specificity, Polymorphism, Single Nucleotide, Prognosis, Resorcinols, Signal Transduction, Transcriptome
Added October 8, 2021
0 Communities
1 Members
0 Resources
17 MeSH Terms
Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4 T cells.
Hoek KL, Greer MJ, McClanahan KG, Nazmi A, Piazuelo MB, Singh K, Wilson KT, Olivares-Villagómez D
(2021) Mucosal Immunol 14: 1088-1099
MeSH Terms: Animals, Biomarkers, CD4-Positive T-Lymphocytes, Cell Differentiation, Cell Transplantation, Cytokines, Disease Susceptibility, Female, Gene Expression Profiling, Gene Expression Regulation, Granzymes, Immune Reconstitution, Immunophenotyping, Interleukin-17, Intraepithelial Lymphocytes, Lymphocyte Activation, Male, Mice, Mice, Knockout, Mice, Transgenic, T-Lymphocyte Subsets, T-Lymphocytes, Helper-Inducer
Added July 1, 2021
0 Communities
1 Members
0 Resources
22 MeSH Terms
KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models.
West JD, Austin ED, Rizzi EM, Yan L, Tanjore H, Crabtree AL, Moore CS, Muthian G, Carrier EJ, Jacobson DA, Hamid R, Kendall PL, Majka S, Rathinasabapathy A
(2021) Int J Mol Sci 22:
MeSH Terms: Animals, Biomarkers, Case-Control Studies, Cytokines, Disease Models, Animal, Disease Susceptibility, Gene Expression Profiling, Genetic Predisposition to Disease, Humans, Hypoxia, Immunomodulation, Lymphocytes, Mice, Mice, Knockout, Models, Biological, Monocytes, Mutation, Nerve Tissue Proteins, Potassium Channels, Tandem Pore Domain, Pulmonary Arterial Hypertension, Transcriptome
Added June 14, 2021
0 Communities
1 Members
0 Resources
21 MeSH Terms
Over-Generalizing About GC (Hypoxia): Pitfalls of Limiting Breadth of Experimental Systems and Analyses in Framing Informatics Conclusions.
Boothby MR, Raybuck A, Cho SH, Stengel KR, Haase VH, Hiebert S, Li J
(2021) Front Immunol 12: 664249
MeSH Terms: Animals, B-Lymphocytes, Biomarkers, Computational Biology, Energy Metabolism, Gene Expression Profiling, Gene Expression Regulation, Germinal Center, Humans, Hypoxia, Immunomodulation, Mice, Transgenic
Added May 28, 2021
0 Communities
1 Members
0 Resources
12 MeSH Terms
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ, GTEx Consortium, Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB
(2021) Cell 184: 2633-2648.e19
MeSH Terms: Coronary Artery Disease, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Disease, Gene Expression Profiling, Genetic Variation, Humans, Inflammatory Bowel Diseases, Multifactorial Inheritance, Organ Specificity, Population, Quantitative Trait Loci, RNA, Long Noncoding, Transcriptome
Added April 18, 2021
0 Communities
1 Members
0 Resources
14 MeSH Terms
An integrative systems-based analysis of substance use: eQTL-informed gene-based tests, gene networks, and biological mechanisms.
Gerring ZF, Vargas AM, Gamazon ER, Derks EM
(2021) Am J Med Genet B Neuropsychiatr Genet 186: 162-172
MeSH Terms: Gene Expression Profiling, Gene Regulatory Networks, Genetic Predisposition to Disease, Genetic Testing, Genome-Wide Association Study, Humans, Phenotype, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Substance-Related Disorders
Added December 30, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
Zhou D, Jiang Y, Zhong X, Cox NJ, Liu C, Gamazon ER
(2020) Nat Genet 52: 1239-1246
MeSH Terms: Animals, Gene Expression Profiling, Genetic Association Studies, Humans, Lipoproteins, LDL, Mendelian Randomization Analysis, Mice, Models, Genetic, Multifactorial Inheritance, Predictive Value of Tests
Added October 7, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
A Quantitative Proteome Map of the Human Body.
Jiang L, Wang M, Lin S, Jian R, Li X, Chan J, Dong G, Fang H, Robinson AE, GTEx Consortium, Snyder MP
(2020) Cell 183: 269-283.e19
MeSH Terms: Gene Expression, Gene Expression Profiling, Humans, Proteome, Proteomics, RNA, RNA, Messenger, Transcriptome
Added September 15, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.
Brubaker DK, Kumar MP, Chiswick EL, Gregg C, Starchenko A, Vega PN, Southard-Smith AN, Simmons AJ, Scoville EA, Coburn LA, Wilson KT, Lau KS, Lauffenburger DA
(2020) Sci Signal 13:
MeSH Terms: Animals, Cells, Cultured, Disease Models, Animal, Drug Resistance, Gastrointestinal Agents, Gene Expression Profiling, Humans, Inflammatory Bowel Diseases, Infliximab, Integrin alpha1, Integrins, Male, Mice, Proteomics, RNA-Seq, Signal Transduction, Single-Cell Analysis, Species Specificity, Translational Research, Biomedical
Added August 6, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Long non-coding RNA enhances chondrogenesis via suppression of the interferon type II signaling pathway.
Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F
(2020) Elife 9:
MeSH Terms: Binding Sites, Cell Differentiation, Cells, Cultured, Chondrocytes, Chondrogenesis, Extracellular Matrix, Gene Editing, Gene Expression Profiling, Gene Expression Regulation, Developmental, Gene Regulatory Networks, Humans, Immunohistochemistry, Interferon-gamma, Mesenchymal Stem Cells, Protein Binding, RNA, Long Noncoding, Signal Transduction
Added March 16, 2021
0 Communities
1 Members
0 Resources
17 MeSH Terms