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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 47

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A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid -1 Hydroxylation Using an Untargeted Metabolomic Approach.
Fekry MI, Xiao Y, Berg JZ, Guengerich FP
(2019) Drug Metab Dispos 47: 1325-1332
MeSH Terms: Animals, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System, Fatty Acids, Unsaturated, Female, Gastrointestinal Tract, Humans, Hydroxylation, Isotope Labeling, Metabolomics, Rats
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Gut Microbiome and Response to Cardiovascular Drugs.
Tuteja S, Ferguson JF
(2019) Circ Genom Precis Med 12: 421-429
MeSH Terms: Animals, Bacteria, Biotransformation, Cardiovascular Agents, Gastrointestinal Microbiome, Gastrointestinal Tract, Humans
Added March 3, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
The PAS Domain-Containing Protein HeuR Regulates Heme Uptake in Campylobacter jejuni.
Johnson JG, Gaddy JA, DiRita VJ
(2016) mBio 7:
MeSH Terms: Animals, Bacterial Proteins, Campylobacter jejuni, Catalase, Chickens, Gastrointestinal Tract, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Heme, Humans, Hydrogen Peroxide, Iron, Mutation
Added April 26, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
The Role of the Microbiome in Gastrointestinal Cancer.
Wroblewski LE, Peek RM, Coburn LA
(2016) Gastroenterol Clin North Am 45: 543-56
MeSH Terms: Adenocarcinoma, Animals, Carcinogenesis, Cell Proliferation, Colonic Polyps, Colorectal Neoplasms, Diet, Disease Models, Animal, Esophageal Neoplasms, Gastrointestinal Microbiome, Gastrointestinal Neoplasms, Gastrointestinal Tract, Helicobacter Infections, Helicobacter pylori, Humans, Inflammation, Microbiota, Stem Cells, Stomach Neoplasms
Added April 6, 2017
0 Communities
2 Members
0 Resources
19 MeSH Terms
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase.
Li B, Wang A, Liu J, Qi Z, Liu X, Yu K, Wu H, Chen C, Hu C, Wang W, Wu J, Hu Z, Ye L, Zou F, Liu F, Wang B, Wang L, Ren T, Zhang S, Bai M, Zhang S, Liu J, Liu Q
(2016) J Med Chem 59: 8456-72
MeSH Terms: Amides, Animals, Cell Line, Tumor, Female, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors, Gastrointestinal Tract, Halogenation, Humans, Methylation, Mice, Mice, Nude, Models, Molecular, Mutation, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-kit, Rats, Sprague-Dawley, Structure-Activity Relationship
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function.
Margolis KG, Li Z, Stevanovic K, Saurman V, Israelyan N, Anderson GM, Snyder I, Veenstra-VanderWeele J, Blakely RD, Gershon MD
(2016) J Clin Invest 126: 2221-35
MeSH Terms: Animals, Autism Spectrum Disorder, Enteric Nervous System, Female, Gastrointestinal Motility, Gastrointestinal Tract, Genetic Variation, Humans, Male, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Models, Animal, Neurogenesis, Pregnancy, Serotonin, Serotonin Plasma Membrane Transport Proteins
Added August 31, 2018
1 Communities
0 Members
0 Resources
MeSH Terms
Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions.
Zhang LS, Davies SS
(2016) Genome Med 8: 46
MeSH Terms: Animals, Diet, Disease Susceptibility, Energy Metabolism, Fatty Acids, Volatile, Gastrointestinal Microbiome, Gastrointestinal Tract, Homeostasis, Humans, Indoles, Metabolome, Metabolomics, Methylamines, Microbiota, Translational Medical Research, Tryptophan, Tyrosine
Added May 6, 2016
2 Communities
2 Members
0 Resources
17 MeSH Terms
Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association.
Ferguson JF, Allayee H, Gerszten RE, Ideraabdullah F, Kris-Etherton PM, Ordovás JM, Rimm EB, Wang TJ, Bennett BJ, American Heart Association Council on Functional Genomics and Translational Biology, Council on Epidemiology and Prevention, and Stroke Council
(2016) Circ Cardiovasc Genet 9: 291-313
MeSH Terms: American Heart Association, Animals, Biomedical Research, Cardiovascular Diseases, Diet, Diffusion of Innovation, Epigenesis, Genetic, Forecasting, Gastrointestinal Microbiome, Gastrointestinal Tract, Gene-Environment Interaction, Genetic Predisposition to Disease, Genetic Variation, Host-Pathogen Interactions, Humans, Metagenomics, Nutrigenomics, Nutrition Assessment, Nutritional Status, Phenotype, Preventive Health Services, Risk Assessment, Risk Factors, United States
Added June 14, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
IL-17a and IL-22 Induce Expression of Antimicrobials in Gastrointestinal Epithelial Cells and May Contribute to Epithelial Cell Defense against Helicobacter pylori.
Dixon BR, Radin JN, Piazuelo MB, Contreras DC, Algood HM
(2016) PLoS One 11: e0148514
MeSH Terms: Animals, Anti-Infective Agents, CD4-Positive T-Lymphocytes, Epithelial Cells, Epithelium, Gastritis, Gastrointestinal Tract, Helicobacter Infections, Helicobacter pylori, Humans, Inflammation, Interleukin-17, Interleukin-8, Interleukins, Leukocyte L1 Antigen Complex, Lipocalins, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Real-Time Polymerase Chain Reaction, Stomach
Added April 28, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
MICROBIOME. Rethinking heritability of the microbiome.
van Opstal EJ, Bordenstein SR
(2015) Science 349: 1172-3
MeSH Terms: Gastrointestinal Tract, Humans, Microbiota, Quantitative Trait, Heritable, Symbiosis
Added October 8, 2015
0 Communities
1 Members
0 Resources
5 MeSH Terms