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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 52

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iNKT Cell Activation Exacerbates the Development of Huntington's Disease in R6/2 Transgenic Mice.
Park HJ, Lee SW, Im W, Kim M, Van Kaer L, Hong S
(2019) Mediators Inflamm 2019: 3540974
MeSH Terms: Animals, Brain, Cytokines, Disease Models, Animal, Disease Progression, Galactosylceramides, Genotype, Huntington Disease, Leukocytes, Lymphocyte Activation, Mice, Mice, Knockout, Natural Killer T-Cells
Added March 26, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model.
Lee SW, Park HJ, Van Kaer L, Hong S, Hong S
(2018) Sci Rep 8: 10081
MeSH Terms: Animals, Antigens, CD1d, Cell Polarity, Dendritic Cells, Disease Models, Animal, Galactosylceramides, Graphite, Humans, Inflammation, Intraepithelial Lymphocytes, Lymphocyte Activation, Mice, Nanotubes, Carbon, Natural Killer T-Cells, Sepsis, Toll-Like Receptor 4, Transforming Growth Factor beta
Added March 26, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine.
Li B, Siuta M, Bright V, Koktysh D, Matlock BK, Dumas ME, Zhu M, Holt A, Stec D, Deng S, Savage PB, Joyce S, Pham W
(2016) Int J Nanomedicine 11: 6103-6121
MeSH Terms: Adjuvants, Immunologic, Administration, Intranasal, Animals, Cell Death, Cell Proliferation, Dendritic Cells, Galactosylceramides, Immunization, Injections, Intraperitoneal, Lactic Acid, Mice, Mice, Inbred C57BL, Microscopy, Atomic Force, Nanoparticles, Ovalbumin, Polyglycolic Acid, Polylactic Acid-Polyglycolic Acid Copolymer, T-Lymphocytes, Vaccines
Added March 21, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice.
Satoh M, Hoshino M, Fujita K, Iizuka M, Fujii S, Clingan CS, Van Kaer L, Iwabuchi K
(2016) Sci Rep 6: 28473
MeSH Terms: 3T3-L1 Cells, Adipocytes, Adiponectin, Animals, Antigen Presentation, Antigens, CD1d, B7-1 Antigen, Diet, High-Fat, Disease Models, Animal, Disease Progression, Galactosylceramides, Insulin Resistance, Interferon-gamma, Lymphocyte Activation, Macrophage Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Natural Killer T-Cells, Obesity
Added July 30, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Natural killer T cells in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Van Kaer L, Wu L, Parekh VV
(2015) Immunology 146: 1-10
MeSH Terms: Animals, Antigens, CD1d, Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental, Galactosylceramides, Humans, Immunotherapy, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Multiple Sclerosis, Natural Killer T-Cells
Added September 28, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms
Activated invariant NKT cells control central nervous system autoimmunity in a mechanism that involves myeloid-derived suppressor cells.
Parekh VV, Wu L, Olivares-Villagómez D, Wilson KT, Van Kaer L
(2013) J Immunol 190: 1948-60
MeSH Terms: Adoptive Transfer, Animals, Antigen Presentation, Autoimmunity, Cell Communication, Cell Movement, Cell Proliferation, Central Nervous System, Encephalomyelitis, Autoimmune, Experimental, Female, Galactosylceramides, Granulocyte-Macrophage Colony-Stimulating Factor, Interferon-gamma, Interleukin-4, Mice, Mice, Transgenic, Myeloid Cells, Natural Killer T-Cells, Nitric Oxide Synthase Type II, Spleen, Transplantation Chimera, Whole-Body Irradiation
Added March 5, 2014
0 Communities
4 Members
0 Resources
22 MeSH Terms
Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice.
Wu L, Parekh VV, Gabriel CL, Bracy DP, Marks-Shulman PA, Tamboli RA, Kim S, Mendez-Fernandez YV, Besra GS, Lomenick JP, Williams B, Wasserman DH, Van Kaer L
(2012) Proc Natl Acad Sci U S A 109: E1143-52
MeSH Terms: Adipose Tissue, White, Animals, Antigens, CD1d, CD8-Positive T-Lymphocytes, Cells, Cultured, Cytokines, Dietary Fats, Fatty Liver, Female, Flow Cytometry, Galactosylceramides, Inflammation, Inflammation Mediators, Insulin Resistance, Lipids, Lymphocyte Activation, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Natural Killer T-Cells, Obesity
Added March 4, 2013
1 Communities
4 Members
0 Resources
23 MeSH Terms
NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors.
Joyce S, Girardi E, Zajonc DM
(2011) J Immunol 187: 1081-9
MeSH Terms: Animals, Antigen Presentation, Galactosylceramides, Glycolipids, Humans, Immunological Synapses, Inflammation, Inflammation Mediators, Ligands, Lipid Metabolism, Natural Killer T-Cells
Added May 19, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens.
Van Kaer L, Parekh VV, Wu L
(2011) Immunotherapy 3: 59-75
MeSH Terms: Animals, Antigen Presentation, Antigens, Autoimmune Diseases, Clinical Trials as Topic, Galactosylceramides, Glycolipids, Humans, Immunotherapy, Infections, Mice, Mice, Inbred C57BL, Natural Killer T-Cells, Neoplasms, Treatment Outcome
Added March 20, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia.
Braun NA, Mendez-Fernandez YV, Covarrubias R, Porcelli SA, Savage PB, Yagita H, Van Kaer L, Major AS
(2010) Arterioscler Thromb Vasc Biol 30: 1758-65
MeSH Terms: Animals, Antigen-Presenting Cells, Antigens, Surface, Apolipoproteins E, Apoptosis Regulatory Proteins, Cell Proliferation, Cells, Cultured, Chronic Disease, Clonal Anergy, Cytokines, Dendritic Cells, Disease Models, Animal, Galactosylceramides, Hyperlipidemias, Injections, Intraperitoneal, Interleukin-2, Lymphocyte Activation, Lymphocyte Count, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, NK Cell Lectin-Like Receptor Subfamily A, Natural Killer T-Cells, Phenotype, Programmed Cell Death 1 Receptor, Receptors, Antigen, T-Cell, Time Factors
Added February 11, 2014
0 Communities
2 Members
0 Resources
28 MeSH Terms