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The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model.
Hawkins NA, Lewis M, Hammond RS, Doherty JJ, Kearney JA
(2017) Sci Rep 7: 15327
MeSH Terms: Animals, Anticonvulsants, Epilepsies, Myoclonic, GABA-A Receptor Agonists, Hydroxycholesterols, Mice, Mice, Mutant Strains, NAV1.1 Voltage-Gated Sodium Channel, Receptors, GABA-A
Added October 2, 2018
1 Communities
0 Members
0 Resources
9 MeSH Terms
Effects of Antecedent GABA A Receptor Activation on Counterregulatory Responses to Exercise in Healthy Man.
Hedrington MS, Tate DB, Younk LM, Davis SN
(2015) Diabetes 64: 3253-61
MeSH Terms: Adult, Alprazolam, Autonomic Nervous System, Bicycling, Blood Glucose, Epinephrine, Exercise, Female, GABA-A Receptor Agonists, Glucagon, Glucose Clamp Technique, Human Growth Hormone, Humans, Hydrocortisone, Lipolysis, Male, Norepinephrine, Pituitary-Adrenal System, Receptors, GABA-A
Added July 30, 2015
0 Communities
0 Members
2 Resources
19 MeSH Terms