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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 35

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To Avoid Chasing Incorrect Chemical Structures of Chiral Compounds: Raman Optical Activity and Vibrational Circular Dichroism Spectroscopies.
Polavarapu PL, Covington CL, Raghavan V
(2017) Chemphyschem 18: 2459-2465
MeSH Terms: Alcohols, Alkynes, Circular Dichroism, Furans, Ketones, Lactones, Molecular Structure, Quantum Theory, Sesquiterpenes, Spectrum Analysis, Raman
Added April 10, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 3. Engineering plasma stability by discovery and optimization of isoindolinone analogs.
Garcia-Barrantes PM, Cho HP, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW
(2016) Bioorg Med Chem Lett 26: 1869-72
MeSH Terms: Allosteric Regulation, Central Nervous System, Coumarins, Dose-Response Relationship, Drug, Drug Discovery, Drug Stability, Furans, Humans, Isoindoles, Molecular Structure, Phthalimides, Receptors, Metabotropic Glutamate, Structure-Activity Relationship, Substrate Specificity
Added April 6, 2017
0 Communities
2 Members
0 Resources
14 MeSH Terms
Lead optimization of the VU0486321 series of mGlu(1) PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool.
Garcia-Barrantes PM, Cho HP, Metts AM, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW
(2016) Bioorg Med Chem Lett 26: 751-756
MeSH Terms: Allosteric Regulation, Animals, Antipsychotic Agents, Coumarins, Furans, Half-Life, Heterocyclic Compounds, Humans, Protein Binding, Rats, Receptors, Metabotropic Glutamate, Schizophrenia, Structure-Activity Relationship
Added February 18, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core.
Garcia-Barrantes PM, Cho HP, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW
(2015) Bioorg Med Chem Lett 25: 5107-10
MeSH Terms: Allosteric Regulation, Animals, Brain, Coumarins, Furans, Humans, Microsomes, Liver, Phthalimides, Rats, Receptors, Metabotropic Glutamate, Stereoisomerism, Structure-Activity Relationship
Added February 18, 2016
0 Communities
2 Members
0 Resources
12 MeSH Terms
Association of plasma F2-isoprostanes and isofurans concentrations with erythropoiesis-stimulating agent resistance in maintenance hemodialysis patients.
Rivara MB, Ikizler TA, Ellis CD, Mehrotra R, Himmelfarb J
(2015) BMC Nephrol 16: 79
MeSH Terms: Adult, Aged, Anemia, C-Reactive Protein, Drug Resistance, F2-Isoprostanes, Female, Furans, Hematinics, Humans, Inflammation, Interleukin-6, Iron, Kidney Failure, Chronic, Linear Models, Male, Middle Aged, Oxidative Stress, Prospective Studies, Renal Dialysis
Added August 5, 2015
0 Communities
2 Members
0 Resources
20 MeSH Terms
PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.
Perrone MG, Malerba P, Uddin J, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A
(2014) Eur J Med Chem 80: 562-568
MeSH Terms: Animals, Biomarkers, Tumor, Cell Line, Tumor, Cell Transformation, Neoplastic, Cyclooxygenase 1, Cyclooxygenase Inhibitors, Female, Fluorine Radioisotopes, Furans, Humans, Isoxazoles, Mice, Ovarian Neoplasms, Positron-Emission Tomography, Radioactive Tracers, Radiochemistry, Tomography, X-Ray Computed
Added May 20, 2014
0 Communities
3 Members
0 Resources
17 MeSH Terms
Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro.
Spinelli SL, Lannan KL, Casey AE, Croasdell A, Curran TM, Henrichs KF, Pollock SJ, Milne GA, Refaai MA, Francis CW, Phipps RP, Blumberg N
(2014) Transfusion 54: 1569-79
MeSH Terms: Blood Platelets, Dinoprost, Erythrocytes, F2-Isoprostanes, Furans, Humans, Immunoassay, Isoprostanes, Reactive Oxygen Species
Added March 26, 2014
1 Communities
1 Members
0 Resources
9 MeSH Terms
New insights regarding tissue Se and Hg interactions on oxidative stress from plasma IsoP and IsoF measures in the Canadian Inuit population.
Alkazemi D, Egeland GM, Roberts LJ, Chan HM, Kubow S
(2013) J Lipid Res 54: 1972-9
MeSH Terms: Adolescent, Adult, Canada, F2-Isoprostanes, Female, Furans, Humans, Male, Mercury, Multivariate Analysis, Oxidative Stress, Selenium, Young Adult
Added March 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Measurement of F2- isoprostanes and isofurans using gas chromatography-mass spectrometry.
Milne GL, Gao B, Terry ES, Zackert WE, Sanchez SC
(2013) Free Radic Biol Med 59: 36-44
MeSH Terms: F2-Isoprostanes, Furans, Gas Chromatography-Mass Spectrometry, Humans, Oxidative Stress
Added December 5, 2013
2 Communities
1 Members
0 Resources
5 MeSH Terms
Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress.
Bastarache JA, Sebag SC, Clune JK, Grove BS, Lawson WE, Janz DR, Roberts LJ, Dworski R, Mackman N, Ware LB
(2012) Thorax 67: 1032-9
MeSH Terms: Acute Lung Injury, Analysis of Variance, Animals, Blotting, Western, Bronchoalveolar Lavage, Cytokines, Electrophoresis, Polyacrylamide Gel, Furans, Hemoglobins, Hemorrhage, Inflammation, Isoprostanes, Lipopolysaccharides, Mice, Mice, Knockout, Oxidative Stress, Pulmonary Alveoli, Real-Time Polymerase Chain Reaction, Statistics, Nonparametric, Thromboplastin
Added March 7, 2014
0 Communities
3 Members
0 Resources
20 MeSH Terms