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Results: 1 to 10 of 135

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Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species.
Lind AL, Wisecaver JH, Lameiras C, Wiemann P, Palmer JM, Keller NP, Rodrigues F, Goldman GH, Rokas A
(2017) PLoS Biol 15: e2003583
MeSH Terms: Alleles, Aspergillus fumigatus, Biological Evolution, Fungal Proteins, Fungi, Genetic Variation, Genome, Fungal, Genomics, Metabolic Networks and Pathways, Multigene Family, Mutation, Polymorphism, Genetic, Secondary Metabolism
Added March 21, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Role of Calprotectin in Withholding Zinc and Copper from Candida albicans.
Besold AN, Gilston BA, Radin JN, Ramsoomair C, Culbertson EM, Li CX, Cormack BP, Chazin WJ, Kehl-Fie TE, Culotta VC
(2018) Infect Immun 86:
MeSH Terms: Animals, Candida albicans, Copper, Fungal Proteins, Homeostasis, Leukocyte L1 Antigen Complex, Mice, Mice, Inbred C57BL, Mice, Knockout, Zinc
Added March 24, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
MybA, a transcription factor involved in conidiation and conidial viability of the human pathogen Aspergillus fumigatus.
Valsecchi I, Sarikaya-Bayram Ö, Wong Sak Hoi J, Muszkieta L, Gibbons J, Prevost MC, Mallet A, Krijnse-Locker J, Ibrahim-Granet O, Mouyna I, Carr P, Bromley M, Aimanianda V, Yu JH, Rokas A, Braus GH, Saveanu C, Bayram Ö, Latgé JP
(2017) Mol Microbiol 105: 880-900
MeSH Terms: Aspergillosis, Aspergillus fumigatus, Cell Wall, Fungal Proteins, Gene Deletion, Gene Expression Regulation, Fungal, Humans, Membrane Proteins, Sequence Deletion, Spores, Fungal, Transcription Factors, Virulence
Added March 21, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
WetA bridges cellular and chemical development in Aspergillus flavus.
Wu MY, Mead ME, Kim SC, Rokas A, Yu JH
(2017) PLoS One 12: e0179571
MeSH Terms: Aspergillus flavus, Cell Survival, Fungal Proteins, Gene Expression Regulation, Fungal, Genes, Fungal, Hyphae, Reproduction, Asexual
Added March 21, 2018
0 Communities
1 Members
0 Resources
7 MeSH Terms
Structural analyses of sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis.
Hargrove TY, Friggeri L, Wawrzak Z, Qi A, Hoekstra WJ, Schotzinger RJ, York JD, Guengerich FP, Lepesheva GI
(2017) J Biol Chem 292: 6728-6743
MeSH Terms: Animals, Antifungal Agents, Azoles, Candida albicans, Crystallization, Fungal Proteins, Heme, Humans, Kinetics, Ligands, Microbial Sensitivity Tests, Protein Binding, Protein Conformation, Protons, Rats, Sterol 14-Demethylase, Sterols
Added March 14, 2018
0 Communities
3 Members
0 Resources
17 MeSH Terms
Regulation of Secondary Metabolism by the Velvet Complex Is Temperature-Responsive in Aspergillus.
Lind AL, Smith TD, Saterlee T, Calvo AM, Rokas A
(2016) G3 (Bethesda) 6: 4023-4033
MeSH Terms: Aspergillus, Cluster Analysis, Fungal Proteins, Gene Expression Profiling, Gene Expression Regulation, Fungal, Multigene Family, Secondary Metabolism, Temperature
Added April 6, 2017
0 Communities
1 Members
0 Resources
8 MeSH Terms
Comparative genomics of biotechnologically important yeasts.
Riley R, Haridas S, Wolfe KH, Lopes MR, Hittinger CT, Göker M, Salamov AA, Wisecaver JH, Long TM, Calvey CH, Aerts AL, Barry KW, Choi C, Clum A, Coughlan AY, Deshpande S, Douglass AP, Hanson SJ, Klenk HP, LaButti KM, Lapidus A, Lindquist EA, Lipzen AM, Meier-Kolthoff JP, Ohm RA, Otillar RP, Pangilinan JL, Peng Y, Rokas A, Rosa CA, Scheuner C, Sibirny AA, Slot JC, Stielow JB, Sun H, Kurtzman CP, Blackwell M, Grigoriev IV, Jeffries TW
(2016) Proc Natl Acad Sci U S A 113: 9882-7
MeSH Terms: Ascomycota, Biotechnology, Evolution, Molecular, Fungal Proteins, Genetic Code, Genome, Fungal, Genomics, Metabolic Networks and Pathways, Phylogeny, Species Specificity, Yeasts
Added April 6, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms
Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.
Hargrove TY, Wawrzak Z, Lamb DC, Guengerich FP, Lepesheva GI
(2015) J Biol Chem 290: 23916-34
MeSH Terms: Aspergillus fumigatus, Catalysis, Cytochrome P-450 Enzyme System, Drug Resistance, Fungal, Fungal Proteins, Protein Structure, Tertiary, Structure-Activity Relationship, Voriconazole
Added March 14, 2018
0 Communities
2 Members
0 Resources
8 MeSH Terms
In-depth comparative proteomic analysis of yeast proteome using iTRAQ and SWATH based MS.
Basak T, Bhat A, Malakar D, Pillai M, Sengupta S
(2015) Mol Biosyst 11: 2135-43
MeSH Terms: Chromatography, Liquid, Fungal Proteins, Gene Expression Regulation, Fungal, Proteome, Proteomics, Saccharomyces cerevisiae, Tandem Mass Spectrometry
Added November 3, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms
Fungal prion HET-s as a model for structural complexity and self-propagation in prions.
Wan W, Stubbs G
(2014) Proc Natl Acad Sci U S A 111: 5201-6
MeSH Terms: Asparagine, Fungal Proteins, Kinetics, Models, Structural, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Podospora, Prions, Protein Conformation, Surface Properties, X-Ray Diffraction
Added February 15, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms