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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 24

Publication Record

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Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis.
Dear ML, Shilts J, Broadie K
(2017) Sci Signal 10:
MeSH Terms: Animals, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Syndrome, Heparan Sulfate Proteoglycans, Matrix Metalloproteinase 1, Matrix Metalloproteinase 2, Neuromuscular Junction, Neurons, Presynaptic Terminals, Proteoglycans, Wnt Signaling Pathway
Added December 7, 2017
1 Communities
0 Members
0 Resources
13 MeSH Terms
Altered Neuronal and Circuit Excitability in Fragile X Syndrome.
Contractor A, Klyachko VA, Portera-Cailliau C
(2015) Neuron 87: 699-715
MeSH Terms: Animals, Brain, Fragile X Mental Retardation Protein, Fragile X Syndrome, Humans, Nerve Net, Neurons, Synapses
Added February 8, 2016
1 Communities
0 Members
0 Resources
8 MeSH Terms
GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model.
Gatto CL, Pereira D, Broadie K
(2014) Neurobiol Dis 65: 142-59
MeSH Terms: Animals, Animals, Genetically Modified, Association Learning, Calcium Signaling, Cell Count, Disease Models, Animal, Drosophila, Drosophila Proteins, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Expression Regulation, Glutamate Decarboxylase, Green Fluorescent Proteins, Luminescent Proteins, Mushroom Bodies, Nerve Net, Olfactory Bulb, Synapses, Time Factors, gamma-Aminobutyric Acid
Added March 29, 2017
1 Communities
1 Members
0 Resources
20 MeSH Terms
Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome.
Siller SS, Broadie K
(2012) Neural Plast 2012: 124548
MeSH Terms: Animals, Disease Models, Animal, Drosophila, Fragile X Syndrome, Humans, Matrix Metalloproteinase Inhibitors, Matrix Metalloproteinases, Mice, Minocycline, Protease Inhibitors
Added March 29, 2017
1 Communities
1 Members
0 Resources
10 MeSH Terms
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.
Coffee RL, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K
(2012) Hum Mol Genet 21: 900-15
MeSH Terms: Animals, Animals, Genetically Modified, Brain, Cytoskeleton, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Humans, Learning, Microtubule-Associated Proteins, Mutation, Neuromuscular Junction, Neurons, Phosphorylation, Phosphoserine, Protein Biosynthesis, Serine, Transgenes
Added May 29, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase.
Siller SS, Broadie K
(2011) Dis Model Mech 4: 673-85
MeSH Terms: Animals, Cell Shape, Circadian Clocks, Disease Models, Animal, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Deletion, Matrix Metalloproteinase 1, Minocycline, Mushroom Bodies, Nerve Net, Neuromuscular Junction, Neurons, Phenotype, Synapses, Tissue Inhibitor of Metalloproteinases
Added March 29, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
The fragile X mental retardation protein developmentally regulates the strength and fidelity of calcium signaling in Drosophila mushroom body neurons.
Tessier CR, Broadie K
(2011) Neurobiol Dis 41: 147-59
MeSH Terms: Animals, Calcium, Calcium Signaling, Calcium-Binding Proteins, Cells, Cultured, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Expression Regulation, Developmental, Membrane Potentials, Mushroom Bodies, Neurons
Added March 29, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Prevalence of the fragile X syndrome in African-Americans.
Crawford DC, Meadows KL, Newman JL, Taft LF, Scott E, Leslie M, Shubek L, Holmgreen P, Yeargin-Allsopp M, Boyle C, Sherman SL
(2002) Am J Med Genet 110: 226-33
MeSH Terms: African Continental Ancestry Group, Alleles, Child, Female, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Frequency, Humans, Male, Mutation, Nerve Tissue Proteins, Prevalence, RNA-Binding Proteins, Trinucleotide Repeats, United States
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Paternally transmitted FMR1 alleles are less stable than maternally transmitted alleles in the common and intermediate size range.
Sullivan AK, Crawford DC, Scott EH, Leslie ML, Sherman SL
(2002) Am J Hum Genet 70: 1532-44
MeSH Terms: African Continental Ancestry Group, Alleles, European Continental Ancestry Group, Fathers, Female, Fragile X Mental Retardation Protein, Fragile X Syndrome, Haplotypes, Humans, Intellectual Disability, Logistic Models, Male, Mothers, Mutagenesis, Nerve Tissue Proteins, RNA-Binding Proteins, Risk Factors, Trinucleotide Repeat Expansion
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
FMR1 and the fragile X syndrome: human genome epidemiology review.
Crawford DC, Acuña JM, Sherman SL
(2001) Genet Med 3: 359-71
MeSH Terms: European Continental Ancestry Group, Female, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Frequency, Genetic Testing, Genome, Human, Heterozygote, Humans, Male, Mutation, Nerve Tissue Proteins, RNA-Binding Proteins, Trinucleotide Repeats
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms