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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 21

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Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry.
Doll CA, Broadie K
(2016) Neurobiol Dis 89: 76-87
MeSH Terms: Animals, Animals, Genetically Modified, Calcium Signaling, Cholinergic Neurons, Critical Period, Psychological, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, GABAergic Neurons, Gene Knockout Techniques, Learning, Memory, Mushroom Bodies, Neurons
Added March 29, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms
Altered Neuronal and Circuit Excitability in Fragile X Syndrome.
Contractor A, Klyachko VA, Portera-Cailliau C
(2015) Neuron 87: 699-715
MeSH Terms: Animals, Brain, Fragile X Mental Retardation Protein, Fragile X Syndrome, Humans, Nerve Net, Neurons, Synapses
Added February 8, 2016
1 Communities
0 Members
0 Resources
8 MeSH Terms
Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory.
Doll CA, Broadie K
(2015) Development 142: 1346-56
MeSH Terms: Animals, Dendrites, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Gene Knockdown Techniques, Gene Targeting, Memory, Mushroom Bodies, Mutation, Nerve Net, Time Factors
Added March 29, 2017
1 Communities
1 Members
0 Resources
12 MeSH Terms
GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model.
Gatto CL, Pereira D, Broadie K
(2014) Neurobiol Dis 65: 142-59
MeSH Terms: Animals, Animals, Genetically Modified, Association Learning, Calcium Signaling, Cell Count, Disease Models, Animal, Drosophila, Drosophila Proteins, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Expression Regulation, Glutamate Decarboxylase, Green Fluorescent Proteins, Luminescent Proteins, Mushroom Bodies, Nerve Net, Olfactory Bulb, Synapses, Time Factors, gamma-Aminobutyric Acid
Added March 29, 2017
1 Communities
1 Members
0 Resources
20 MeSH Terms
Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila.
Friedman SH, Dani N, Rushton E, Broadie K
(2013) Dis Model Mech 6: 1400-13
MeSH Terms: Animals, Drosophila, Fragile X Mental Retardation Protein, Signal Transduction, Synapses, Up-Regulation
Added March 29, 2017
1 Communities
1 Members
0 Resources
6 MeSH Terms
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.
Coffee RL, Williamson AJ, Adkins CM, Gray MC, Page TL, Broadie K
(2012) Hum Mol Genet 21: 900-15
MeSH Terms: Animals, Animals, Genetically Modified, Brain, Cytoskeleton, Disease Models, Animal, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Humans, Learning, Microtubule-Associated Proteins, Mutation, Neuromuscular Junction, Neurons, Phosphorylation, Phosphoserine, Protein Biosynthesis, Serine, Transgenes
Added May 29, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase.
Siller SS, Broadie K
(2011) Dis Model Mech 4: 673-85
MeSH Terms: Animals, Cell Shape, Circadian Clocks, Disease Models, Animal, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Deletion, Matrix Metalloproteinase 1, Minocycline, Mushroom Bodies, Nerve Net, Neuromuscular Junction, Neurons, Phenotype, Synapses, Tissue Inhibitor of Metalloproteinases
Added March 29, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
Fragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons.
Gatto CL, Broadie K
(2011) Dev Biol 356: 291-307
MeSH Terms: Animals, Apoptosis, Calcium, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Gene Expression Regulation, Developmental, Neurons, Neuropeptides
Added March 29, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
The fragile X mental retardation protein developmentally regulates the strength and fidelity of calcium signaling in Drosophila mushroom body neurons.
Tessier CR, Broadie K
(2011) Neurobiol Dis 41: 147-59
MeSH Terms: Animals, Calcium, Calcium Signaling, Calcium-Binding Proteins, Cells, Cultured, Drosophila Proteins, Drosophila melanogaster, Fragile X Mental Retardation Protein, Fragile X Syndrome, Gene Expression Regulation, Developmental, Membrane Potentials, Mushroom Bodies, Neurons
Added March 29, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.
Coffee RL, Tessier CR, Woodruff EA, Broadie K
(2010) Dis Model Mech 3: 471-85
MeSH Terms: Animals, Animals, Genetically Modified, Brain, Conserved Sequence, Drosophila Proteins, Drosophila melanogaster, Evolution, Molecular, Fertility, Fragile X Mental Retardation Protein, Humans, Male, Mutation, Nerve Net, Neuromuscular Junction, Neurons, RNA-Binding Proteins, Spermatogenesis, Synapses, Testis
Added March 29, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms