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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 21

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Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.
Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, Blobe GC
(2017) Arterioscler Thromb Vasc Biol 37: 1115-1126
MeSH Terms: Animals, CRISPR-Cas Systems, Cell Movement, Cell Shape, Cells, Cultured, Coculture Techniques, Endoglin, Endothelial Cells, Focal Adhesion Kinase 1, Gene Expression Regulation, Humans, Integrins, Mice, Inbred C57BL, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Phenotype, RNA Interference, Signal Transduction, Transfection
Added March 22, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons.
Meltzer S, Yadav S, Lee J, Soba P, Younger SH, Jin P, Zhang W, Parrish J, Jan LY, Jan YN
(2016) Neuron 89: 741-55
MeSH Terms: Animals, Animals, Genetically Modified, Cell Communication, Dendrites, Drosophila, Drosophila Proteins, Epidermis, Focal Adhesion Kinase 1, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Immunoprecipitation, Larva, Mechanistic Target of Rapamycin Complex 2, Molecular Biology, Multiprotein Complexes, Mutation, Nerve Tissue Proteins, Receptors, Cell Surface, Semaphorins, Sensory Receptor Cells, TOR Serine-Threonine Kinases, Transfection
Added February 9, 2016
1 Communities
0 Members
0 Resources
22 MeSH Terms
SRChing for the substrates of Src.
Reynolds AB, Kanner SB, Bouton AH, Schaller MD, Weed SA, Flynn DC, Parsons JT
(2014) Oncogene 33: 4537-47
MeSH Terms: Animals, Catenins, Cell Transformation, Neoplastic, Cortactin, Crk-Associated Substrate Protein, Focal Adhesion Kinase 1, Gene Expression Regulation, Neoplastic, Humans, Mice, Microfilament Proteins, Neoplasms, Phosphorylation, Proteome, src-Family Kinases
Added March 28, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas.
Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL
(2013) Cancer Res 73: 5336-46
MeSH Terms: Animals, Carcinogenesis, Collagen, Enzyme Inhibitors, Female, Fibroblasts, Focal Adhesion Kinase 1, Humans, In Situ Hybridization, Keratin-14, Lung Neoplasms, Mammary Neoplasms, Experimental, Mice, Mice, Transgenic, Microscopy, Atomic Force, Myeloid Cells, Phosphorylation, Protein-Lysine 6-Oxidase, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Stromal Cells, Transforming Growth Factor beta
Added February 17, 2014
1 Communities
2 Members
0 Resources
24 MeSH Terms
Expression of focal adhesion kinase in small-cell lung carcinoma.
Ocak S, Chen H, Callison C, Gonzalez AL, Massion PP
(2012) Cancer 118: 1293-301
MeSH Terms: Aged, Female, Focal Adhesion Kinase 1, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paxillin, Phosphorylation, Small Cell Lung Carcinoma, Survival Analysis
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Transforming growth factor beta induces clustering of HER2 and integrins by activating Src-focal adhesion kinase and receptor association to the cytoskeleton.
Wang SE, Xiang B, Zent R, Quaranta V, Pozzi A, Arteaga CL
(2009) Cancer Res 69: 475-82
MeSH Terms: Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Breast Neoplasms, Cell Line, Tumor, Cell Membrane, Cytoskeleton, Enzyme Activation, ErbB Receptors, Focal Adhesion Kinase 1, Humans, Integrins, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor Cross-Talk, Receptor, ErbB-2, Transforming Growth Factor beta, Trastuzumab, src-Family Kinases
Added February 24, 2014
3 Communities
3 Members
0 Resources
18 MeSH Terms
Extracellular matrix rigidity promotes invadopodia activity.
Alexander NR, Branch KM, Parekh A, Clark ES, Iwueke IC, Guelcher SA, Weaver AM
(2008) Curr Biol 18: 1295-1299
MeSH Terms: Actin Cytoskeleton, Azepines, Cell Line, Tumor, Cell Surface Extensions, Crk-Associated Substrate Protein, Enzyme Inhibitors, Extracellular Matrix, Focal Adhesion Kinase 1, Gelatin, Heterocyclic Compounds, 4 or More Rings, Humans, Integrins, Myosin Type II, Myosin-Light-Chain Kinase, Naphthalenes, Signal Transduction
Added March 5, 2014
2 Communities
3 Members
0 Resources
16 MeSH Terms
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model.
Park SI, Zhang J, Phillips KA, Araujo JC, Najjar AM, Volgin AY, Gelovani JG, Kim SJ, Wang Z, Gallick GE
(2008) Cancer Res 68: 3323-33
MeSH Terms: Animals, Antineoplastic Agents, Cell Movement, Cell Proliferation, Crk-Associated Substrate Protein, Dasatinib, Disease Models, Animal, Drug Delivery Systems, Focal Adhesion Kinase 1, Humans, Lymphatic Metastasis, Male, Mice, Mice, Nude, Prostatic Neoplasms, Pyrimidines, Thiazoles, Tumor Burden, Tumor Cells, Cultured, Tyrosine, Xenograft Model Antitumor Assays, src-Family Kinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly.
Siesser PM, Meenderink LM, Ryzhova L, Michael KE, Dumbauld DW, García AJ, Kaverina I, Hanks SK
(2008) Cell Motil Cytoskeleton 65: 25-39
MeSH Terms: Actins, Animals, Cells, Cultured, Focal Adhesion Kinase 1, Focal Adhesions, Genes, src, Mice, Phenotype, Proto-Oncogene Proteins pp60(c-src), Recombinant Fusion Proteins, Signal Transduction
Added December 10, 2013
0 Communities
2 Members
0 Resources
11 MeSH Terms
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.
Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK
(2005) Mol Cancer Res 3: 307-15
MeSH Terms: Animals, Binding Sites, Cell Line, Transformed, Cell Movement, Cells, Cultured, Collagen, Cytoskeletal Proteins, Drug Combinations, Enzyme Activation, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Genes, src, Injections, Subcutaneous, Laminin, Lung Neoplasms, Matrix Metalloproteinase 2, Mice, Mice, Nude, Neoplasm Invasiveness, Neoplasm Transplantation, Oncogene Protein v-crk, Paxillin, Phosphoproteins, Phosphorylation, Protein-Tyrosine Kinases, Proteoglycans, Retroviridae Proteins, Oncogenic, Tyrosine, src Homology Domains
Added February 24, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms