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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo.
Blobaum AL, Byers FW, Bridges TM, Locuson CW, Conn PJ, Lindsley CW, Daniels JS
(2015) Drug Metab Dispos 43: 1718-26
MeSH Terms: Androgen Receptor Antagonists, Animals, Cytochrome P-450 CYP3A, Drug Evaluation, Preclinical, Enzyme Activators, Female, Flutamide, Guinea Pigs, Humans, Male, Mice, Microsomes, Liver, Rats, Rats, Sprague-Dawley, Swine, Swine, Miniature
Added February 18, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer.
Lloyd A, Penson D, Dewilde S, Kleinman L
(2008) Prostate Cancer Prostatic Dis 11: 153-9
MeSH Terms: Adenocarcinoma, Aged, Androgen Antagonists, Anilides, Antineoplastic Agents, Hormonal, Choice Behavior, Cross-Sectional Studies, Diarrhea, Drug Administration Schedule, Drug Costs, Drug Therapy, Erectile Dysfunction, Flutamide, Gynecomastia, Health Surveys, Hematuria, Humans, Life Expectancy, Male, Middle Aged, Nitriles, Patient Acceptance of Health Care, Patient Satisfaction, Prostatic Neoplasms, Tosyl Compounds
Added March 5, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade with flutamide?
Ramsey S, Veenstra D, Clarke L, Gandhi S, Hirsch M, Penson D
(2005) Urology 66: 835-9
MeSH Terms: Androgen Antagonists, Anilides, Antineoplastic Agents, Cost-Benefit Analysis, Drug Therapy, Combination, Flutamide, Humans, Male, Nitriles, Prostatic Neoplasms, Tosyl Compounds
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells.
Andriani F, Nan B, Yu J, Li X, Weigel NL, McPhaul MJ, Kasper S, Kagawa S, Fang B, Matusik RJ, Denner L, Marcelli M
(2001) J Natl Cancer Inst 93: 1314-24
MeSH Terms: Adenoviridae, Androgen Antagonists, Androgen-Binding Protein, Animals, Apoptosis, Arabidopsis Proteins, Blotting, Western, DNA-Binding Proteins, Flutamide, Gene Expression Regulation, Neoplastic, Humans, Male, Mice, Promoter Regions, Genetic, Prostatic Neoplasms, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-bcl-2, Receptors, Androgen, Transcription Factors, Transplantation, Heterologous, Tumor Cells, Cultured, Up-Regulation, bcl-2-Associated X Protein
Added June 11, 2010
1 Communities
1 Members
0 Resources
23 MeSH Terms
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.
Buchanan G, Yang M, Harris JM, Nahm HS, Han G, Moore N, Bentel JM, Matusik RJ, Horsfall DJ, Marshall VR, Greenberg NM, Tilley WD
(2001) Mol Endocrinol 15: 46-56
MeSH Terms: Adenocarcinoma, Androgen Antagonists, Androgens, Animals, Binding Sites, COS Cells, Cell Line, DNA, Dihydrotestosterone, Estradiol, Flutamide, Humans, Male, Mice, Mice, Transgenic, Models, Molecular, Mutagenesis, Mutation, Progesterone, Prostatic Neoplasms, Protein Structure, Secondary, Receptors, Androgen, Structure-Activity Relationship, Transcriptional Activation, Transfection
Added June 11, 2010
1 Communities
1 Members
0 Resources
25 MeSH Terms
Effects of flutamide and hydroxy-flutamide on the growth of human benign prostatic hyperplasia cells in primary culture: a preliminary report.
Hallowes R, Cox S, Hayward S, Deshpande N, Towler J
(1991) Anticancer Res 11: 1799-805
MeSH Terms: Aged, Cell Division, Cells, Cultured, Flutamide, Humans, Male, Middle Aged, Prostatic Hyperplasia
Added May 27, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms