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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 66

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Serine Threonine Kinase 17A Maintains the Epithelial State in Colorectal Cancer Cells.
Short SP, Thompson JJ, Bilotta AJ, Chen X, Revetta FL, Washington MK, Williams CS
(2019) Mol Cancer Res 17: 882-894
MeSH Terms: Apoptosis Regulatory Proteins, Cell Line, Tumor, Cell Movement, Colorectal Neoplasms, Epithelial Cells, Epithelial-Mesenchymal Transition, Fluorouracil, HCT116 Cells, Humans, Neoplasm Metastasis, Protein-Serine-Threonine Kinases
Added April 15, 2019
0 Communities
1 Members
0 Resources
11 MeSH Terms
Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized states.
Dürr KL, Chen L, Stein RA, De Zorzi R, Folea IM, Walz T, Mchaourab HS, Gouaux E
(2014) Cell 158: 778-792
MeSH Terms: Animals, Cryoelectron Microscopy, Crystallography, X-Ray, Fluorouracil, Gene Knockout Techniques, Kainic Acid, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Protein Structure, Tertiary, Rats, Receptors, AMPA
Added February 19, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Comparison of FOLFIRI with or without cetuximab in patients with resected stage III colon cancer; NCCTG (Alliance) intergroup trial N0147.
Huang J, Nair SG, Mahoney MR, Nelson GD, Shields AF, Chan E, Goldberg RM, Gill S, Kahlenberg MS, Quesenberry JT, Thibodeau SN, Smyrk TC, Grothey A, Sinicrope FA, Webb TA, Farr GH, Pockaj BA, Berenberg JL, Mooney M, Sargent DJ, Alberts SR, Alliance for Clinical Trials in Oncology
(2014) Clin Colorectal Cancer 13: 100-9
MeSH Terms: Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Humanized, Antineoplastic Combined Chemotherapy Protocols, Camptothecin, Cetuximab, Chemotherapy, Adjuvant, Colonic Neoplasms, Disease-Free Survival, Female, Fluorouracil, Follow-Up Studies, Humans, Leucovorin, Male, Middle Aged, Mutation, Neoplasm Staging, Proto-Oncogene Proteins, Proto-Oncogene Proteins p21(ras), Survival Rate, Treatment Outcome, ras Proteins
Added March 28, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
Zhang B, Zhang B, Chen X, Bae S, Singh K, Washington MK, Datta PK
(2014) Br J Cancer 110: 946-57
MeSH Terms: Animals, Antimetabolites, Antineoplastic, Apoptosis Regulatory Proteins, Cell Cycle Proteins, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Chromones, Colorectal Neoplasms, Drug Resistance, Neoplasm, Enzyme Activation, Enzyme Inhibitors, Fluorouracil, Humans, Inhibitor of Apoptosis Proteins, Mice, Mice, Inbred BALB C, Morpholines, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasm Transplantation, Neovascularization, Pathologic, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Proteins, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins c-bcl-2, Repressor Proteins, Retinoblastoma Protein, Smad4 Protein, Survivin, Up-Regulation, Vascular Endothelial Growth Factor A, Wound Healing, Xenograft Model Antitumor Assays
Added April 12, 2016
0 Communities
1 Members
0 Resources
37 MeSH Terms
Beyond exon 2--the developing story of RAS mutations in colorectal cancer.
Berlin J
(2013) N Engl J Med 369: 1059-60
MeSH Terms: Antibodies, Monoclonal, Antineoplastic Combined Chemotherapy Protocols, Colorectal Neoplasms, ErbB Receptors, Fluorouracil, Genes, ras, Humans, Leucovorin, Organoplatinum Compounds, Panitumumab, Proto-Oncogene Proteins, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins p21(ras), ras Proteins
Added March 20, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Imaging analysis of hepatoblastoma resectability across neoadjuvant chemotherapy.
Murphy AJ, Ayers GD, Hilmes MA, Mukherjee K, Wilson KJ, Allen WM, Fernandez-Pineda I, Shinall MC, Zhao Z, Furman WL, McCarville MB, Davidoff AM, Lovvorn HN
(2013) J Pediatr Surg 48: 1239-48
MeSH Terms: Algorithms, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Chemotherapy, Adjuvant, Cisplatin, Clinical Protocols, Doxorubicin, Female, Fluorouracil, Hepatectomy, Hepatoblastoma, Humans, Image Interpretation, Computer-Assisted, Liver Neoplasms, Magnetic Resonance Imaging, Male, Models, Statistical, Neoadjuvant Therapy, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome, Tumor Burden, Vincristine
Added December 26, 2013
0 Communities
3 Members
0 Resources
23 MeSH Terms
Aflibercept.
Ciombor KK, Berlin J, Chan E
(2013) Clin Cancer Res 19: 1920-5
MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Camptothecin, Clinical Trials, Phase II as Topic, Clinical Trials, Phase III as Topic, Colorectal Neoplasms, Disease-Free Survival, Fluorouracil, Humans, Irinotecan, Leucovorin, Neoplasm Metastasis, Organoplatinum Compounds, Oxaliplatin, Placenta Growth Factor, Pregnancy Proteins, Protein Binding, Randomized Controlled Trials as Topic, Receptors, Vascular Endothelial Growth Factor, Recombinant Fusion Proteins, Treatment Outcome, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor B
Added September 10, 2013
0 Communities
4 Members
0 Resources
22 MeSH Terms
A randomized phase II trial of vismodegib versus placebo with FOLFOX or FOLFIRI and bevacizumab in patients with previously untreated metastatic colorectal cancer.
Berlin J, Bendell JC, Hart LL, Firdaus I, Gore I, Hermann RC, Mulcahy MF, Zalupski MM, Mackey HM, Yauch RL, Graham RA, Bray GL, Low JA
(2013) Clin Cancer Res 19: 258-67
MeSH Terms: Adult, Aged, Aged, 80 and over, Anilides, Antibodies, Monoclonal, Humanized, Antineoplastic Combined Chemotherapy Protocols, Bevacizumab, Camptothecin, Colorectal Neoplasms, Female, Fluorouracil, Humans, Leucovorin, Male, Maximum Tolerated Dose, Middle Aged, Neoplasm Metastasis, Organoplatinum Compounds, Proto-Oncogene Proteins, Proto-Oncogene Proteins p21(ras), Pyridines, Treatment Outcome, ras Proteins
Added March 7, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Identification of novel germline polymorphisms governing capecitabine sensitivity.
O'Donnell PH, Stark AL, Gamazon ER, Wheeler HE, McIlwee BE, Gorsic L, Im HK, Huang RS, Cox NJ, Dolan ME
(2012) Cancer 118: 4063-73
MeSH Terms: Antimetabolites, Antineoplastic, Capecitabine, Deoxycytidine, European Continental Ancestry Group, Female, Fluorouracil, Genome-Wide Association Study, Humans, Male, Polymorphism, Single Nucleotide, Population Surveillance
Added February 22, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Systemic combination therapy of intravenous continuous 5-fluorouracil and subcutaneous pegylated interferon alfa-2a for advanced hepatocellular carcinoma.
Uchino K, Obi S, Tateishi R, Sato S, Kanda M, Sato T, Arano T, Enooku K, Goto E, Masuzaki R, Nakagawa H, Asaoka Y, Kondo Y, Yamashiki N, Goto T, Shiina S, Omata M, Yoshida H, Koike K
(2012) J Gastroenterol 47: 1152-9
MeSH Terms: Adult, Aged, Aged, 80 and over, Antimetabolites, Antineoplastic, Antineoplastic Combined Chemotherapy Protocols, Antiviral Agents, Carcinoma, Hepatocellular, Cohort Studies, Female, Fluorouracil, Humans, Infusions, Intravenous, Injections, Subcutaneous, Interferon-alpha, Japan, Liver Neoplasms, Male, Middle Aged, Polyethylene Glycols, Recombinant Proteins, Retrospective Studies, Survival Rate, Treatment Outcome
Added May 2, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms