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Genetic Variants Associated with Circulating Fibroblast Growth Factor 23.
Robinson-Cohen C, Bartz TM, Lai D, Ikizler TA, Peacock M, Imel EA, Michos ED, Foroud TM, Akesson K, Taylor KD, Malmgren L, Matsushita K, Nethander M, Eriksson J, Ohlsson C, Mellström D, Wolf M, Ljunggren O, McGuigan F, Rotter JI, Karlsson M, Econs MJ, Ix JH, Lutsey PL, Psaty BM, de Boer IH, Kestenbaum BR
(2018) J Am Soc Nephrol 29: 2583-2592
MeSH Terms: Blacks, Cohort Studies, Female, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Genome-Wide Association Study, Humans, Kidney, Male, Phosphates, Polymorphism, Single Nucleotide, RGS Proteins, Sodium-Phosphate Cotransporter Proteins, Type IIa, Vitamin D, Vitamin D3 24-Hydroxylase, Whites
Added January 3, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
FGF23 Concentration and Genotype Are Novel Predictors of Mortality in African Americans With Type 2 Diabetes.
Chan GC, Divers J, Russell GB, Langefeld CD, Wagenknecht LE, Hsu FC, Xu J, Smith SC, Palmer ND, Hicks PJ, Bowden DW, Register TC, Ma L, Carr JJ, Freedman BI
(2018) Diabetes Care 41: 178-186
MeSH Terms: African Americans, Albuminuria, Apolipoprotein L1, Atherosclerosis, Cohort Studies, Creatinine, Diabetes Mellitus, Type 2, Female, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Follow-Up Studies, Genotyping Techniques, Glomerular Filtration Rate, Glycated Hemoglobin A, Humans, Kidney Function Tests, Male, Middle Aged, Proportional Hazards Models, Risk Factors
Added January 10, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER Breast Cancer.
Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL
(2017) Clin Cancer Res 23: 6138-6150
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Disease Models, Animal, Drug Resistance, Neoplasm, Estrogen Receptor Modulators, Estrogen Receptor alpha, Female, Fibroblast Growth Factors, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Mice, Molecular Targeted Therapy, Neoplasm Staging, Protein Kinase Inhibitors, Protein Transport, Receptor, Fibroblast Growth Factor, Type 1, Signal Transduction, Transcription, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney Function.
Zaheer S, de Boer IH, Allison M, Brown JM, Psaty BM, Robinson-Cohen C, Michos ED, Ix JH, Kestenbaum B, Siscovick D, Vaidya A
(2017) J Clin Endocrinol Metab 102: 1387-1395
MeSH Terms: Adiposity, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Glomerular Filtration Rate, Humans, Kidney, Male, Middle Aged, Minerals, Renal Insufficiency, Chronic, Risk Factors
Added September 19, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.
Fontana L, Cummings NE, Arriola Apelo SI, Neuman JC, Kasza I, Schmidt BA, Cava E, Spelta F, Tosti V, Syed FA, Baar EL, Veronese N, Cottrell SE, Fenske RJ, Bertozzi B, Brar HK, Pietka T, Bullock AD, Figenshau RS, Andriole GL, Merrins MJ, Alexander CM, Kimple ME, Lamming DW
(2016) Cell Rep 16: 520-530
MeSH Terms: Adipose Tissue, White, Amino Acids, Branched-Chain, Animals, Blood Glucose, Dietary Proteins, Fibroblast Growth Factors, Gluconeogenesis, Glucose Intolerance, Humans, Insulin-Secreting Cells, Male, Mice, Inbred C57BL, Middle Aged, Obesity, Organ Size, Stress, Physiological
Added August 2, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus.
Freedman BI, Divers J, Russell GB, Palmer ND, Bowden DW, Carr JJ, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Langefeld CD, Hruska KA, Register TC
(2015) Am J Nephrol 42: 391-401
MeSH Terms: Adult, African Americans, Aged, Albuminuria, Blood Pressure, Bone Density, Carotid Arteries, Coronary Vessels, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Follow-Up Studies, Glomerular Filtration Rate, Glycated Hemoglobin A, Humans, Iliac Artery, Kidney Function Tests, Male, Middle Aged, Phosphates, Plaque, Atherosclerotic, Renin-Angiotensin System, Risk Factors, Tomography, X-Ray Computed, Vitamin D
Added September 29, 2016
0 Communities
1 Members
0 Resources
27 MeSH Terms
Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.
Dravis C, Spike BT, Harrell JC, Johns C, Trejo CL, Southard-Smith EM, Perou CM, Wahl GM
(2015) Cell Rep 12: 2035-48
MeSH Terms: Animals, Breast Neoplasms, Cell Culture Techniques, Cell Differentiation, Epithelial Cells, Epithelial-Mesenchymal Transition, Female, Fetus, Fibroblast Growth Factors, Gene Expression Regulation, Developmental, Gene Expression Regulation, Neoplastic, Humans, Mammary Glands, Animal, Mammary Glands, Human, Mesenchymal Stem Cells, Mice, SOXE Transcription Factors, Signal Transduction, Spheroids, Cellular, Tumor Cells, Cultured
Added September 28, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.
Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, Rairdan XY, Lewin-Koh N, Zhang Y, Gutierrez J, Baruch A, Gelzleichter TR, Stevens D, Rajan S, Bainbridge TW, Vernes JM, Meng YG, Ziai J, Soriano RH, Brauer MJ, Chen Y, Stawicki S, Kim HS, Comps-Agrar L, Luis E, Spiess C, Wu Y, Ernst JA, McGuinness OP, Peterson AS, Sonoda J
(2015) EBioMedicine 2: 730-43
MeSH Terms: Adiponectin, Adipose Tissue, Brown, Animals, Antibodies, Bispecific, Cell Line, Energy Metabolism, Fibroblast Growth Factors, HEK293 Cells, Humans, Insulin, Klotho Proteins, Macaca fascicularis, Male, Membrane Proteins, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Obese, Protein Binding, Receptor, Fibroblast Growth Factor, Type 1, Thermogenesis, Weight Loss
Added September 10, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.
Flynn CR, Albaugh VL, Cai S, Cheung-Flynn J, Williams PE, Brucker RM, Bordenstein SR, Guo Y, Wasserman DH, Abumrad NN
(2015) Nat Commun 6: 7715
MeSH Terms: Adaptation, Biological, Anastomosis, Surgical, Animals, Bariatric Surgery, Bile Acids and Salts, Carrier Proteins, Disease Models, Animal, Energy Metabolism, Fibroblast Growth Factors, Gallbladder, Gastrointestinal Microbiome, Intestine, Small, Liver, Male, Membrane Glycoproteins, Mice, Inbred C57BL, Obesity, Random Allocation
Added August 26, 2015
0 Communities
6 Members
0 Resources
18 MeSH Terms
Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm.
Lippmann ES, Williams CE, Ruhl DA, Estevez-Silva MC, Chapman ER, Coon JJ, Ashton RS
(2015) Stem Cell Reports 4: 632-44
MeSH Terms: Fibroblast Growth Factors, Gene Expression Regulation, Developmental, Homeodomain Proteins, Humans, Neural Plate, Organ Specificity, Pluripotent Stem Cells, Signal Transduction, Stem Cells, Transcriptional Activation, Transcriptome, Tretinoin, Wnt Proteins, beta Catenin
Added August 19, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms