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Results: 1 to 9 of 9

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A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coli.
Salamanca-Pinzón SG, Guengerich FP
(2011) Protein Expr Purif 79: 231-6
MeSH Terms: Adrenodoxin, Animals, Blotting, Western, Cattle, Cholecalciferol, Cholesterol, Chromatography, Liquid, Cytochrome P-450 Enzyme System, Escherichia coli, Ferredoxin-NADP Reductase, Genetic Vectors, Humans, Hydroxylation, Mitochondria, NADP, Protein Binding, Protein Engineering, Recombinant Fusion Proteins, Spectrometry, Mass, Electrospray Ionization, Tandem Mass Spectrometry
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner.
Lamb DC, Lei L, Zhao B, Yuan H, Jackson CJ, Warrilow AG, Skaug T, Dyson PJ, Dawson ES, Kelly SL, Hachey DL, Waterman MR
(2010) Appl Environ Microbiol 76: 1975-80
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Arachidonic Acid, Cloning, Molecular, Cytochrome P-450 Enzyme System, DNA Transposable Elements, Escherichia coli, Ferredoxin-NADP Reductase, Ferredoxins, Gene Expression, Mixed Function Oxygenases, Mutagenesis, Insertional, NADP, Streptomyces coelicolor, Substrate Specificity
Added March 20, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
MTR and MTRR polymorphisms, dietary intake, and breast cancer risk.
Shrubsole MJ, Gao YT, Cai Q, Shu XO, Dai Q, Jin F, Zheng W
(2006) Cancer Epidemiol Biomarkers Prev 15: 586-8
MeSH Terms: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase, Adult, Age Distribution, Biomarkers, Tumor, Breast Neoplasms, Case-Control Studies, China, Confidence Intervals, Diet, Female, Ferredoxin-NADP Reductase, Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease, Humans, Incidence, Logistic Models, Middle Aged, Odds Ratio, Polymorphism, Genetic, Prognosis, Risk Assessment, Sensitivity and Specificity, Survival Rate
Added December 10, 2013
0 Communities
4 Members
0 Resources
23 MeSH Terms
Heterologous expression, purification, and properties of human cytochrome P450 27C1.
Wu ZL, Bartleson CJ, Ham AJ, Guengerich FP
(2006) Arch Biochem Biophys 445: 138-46
MeSH Terms: Adrenodoxin, Amino Acid Sequence, Calcifediol, Catalysis, Cholecalciferol, Cholesterol, Cloning, Molecular, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 27, Escherichia coli, Ferredoxin-NADP Reductase, Humans, Mass Spectrometry, Mitochondria, Molecular Sequence Data, Mutation, Organ Specificity, Peptide Fragments, RNA, Messenger, Recombinant Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Role of positively charged residues lys267, lys270, and arg411 of cytochrome p450scc (CYP11A1) in interaction with adrenodoxin.
Strushkevich NV, Azeva TN, Lepesheva GI, Usanov SA
(2005) Biochemistry (Mosc) 70: 664-71
MeSH Terms: Adrenodoxin, Amino Acid Sequence, Amino Acid Substitution, Cholesterol Side-Chain Cleavage Enzyme, Cloning, Molecular, Electron Transport, Ferredoxin-NADP Reductase, Ferredoxins, Mutagenesis, Site-Directed, Protein Binding, Protein Conformation
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Direct expression of adrenodoxin reductase in Escherichia coli and the functional characterization.
Sagara Y, Wada A, Takata Y, Waterman MR, Sekimizu K, Horiuchi T
(1993) Biol Pharm Bull 16: 627-30
MeSH Terms: Adrenal Cortex, Amino Acid Sequence, Animals, Base Sequence, Cattle, Chromatography, Affinity, Culture Media, DNA, Complementary, Electrophoresis, Polyacrylamide Gel, Escherichia coli, Ferredoxin-NADP Reductase, Flavins, Kinetics, Molecular Sequence Data, Plasmids, Recombinant Proteins, Spectrophotometry, Ultraviolet
Added February 12, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia.
Sakai Y, Yanase T, Okabe Y, Hara T, Waterman MR, Takayanagi R, Haji M, Nawata H
(1994) J Clin Endocrinol Metab 79: 1198-201
MeSH Terms: Adolescent, Adrenal Hyperplasia, Congenital, Adrenodoxin, Base Sequence, Cholesterol Side-Chain Cleavage Enzyme, Disorders of Sex Development, Female, Ferredoxin-NADP Reductase, Hormones, Humans, Male, Middle Aged, Mitochondria, Molecular Probes, Molecular Sequence Data, Mutation, Testis
Added February 12, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Flavodoxin and NADPH-flavodoxin reductase from Escherichia coli support bovine cytochrome P450c17 hydroxylase activities.
Jenkins CM, Waterman MR
(1994) J Biol Chem 269: 27401-8
MeSH Terms: Aldehyde-Lyases, Amino Acid Sequence, Animals, Bacterial Proteins, Cattle, Cytochrome P-450 Enzyme System, Enzyme Activation, Escherichia coli, Ferredoxin-NADP Reductase, Flavodoxin, Molecular Sequence Data, NAD, NADH, NADPH Oxidoreductases, NADPH-Ferrihemoprotein Reductase, Progesterone, Rats, Recombinant Proteins, Sequence Alignment, Sequence Homology, Amino Acid, Spectrum Analysis, Steroid 17-alpha-Hydroxylase
Added February 12, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Cell-free synthesis of precursor forms of mitochondrial steroid hydroxylase enzymes of the bovine adrenal cortex.
Kramer RE, Du Bois RN, Simpson ER, Anderson CM, Kashiwagi K, Lambeth JD, Jefcoate CR, Waterman MR
(1982) Arch Biochem Biophys 215: 478-85
MeSH Terms: Adrenal Cortex, Adrenodoxin, Animals, Cattle, Cell-Free System, Cytochrome P-450 Enzyme System, Electrophoresis, Polyacrylamide Gel, Enzyme Precursors, Ferredoxin-NADP Reductase, Mitochondria, Molecular Weight, Steroid Hydroxylases
Added February 12, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms