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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 28

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Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction.
Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ
(2020) Blood 136: 885-897
MeSH Terms: Anemia, Aplastic, Animals, Apoptosis, Cells, Cultured, Fas Ligand Protein, Female, Humans, Immune System Diseases, Immune Tolerance, Interleukin-2, Male, Mice, Mice, Inbred NOD, Mice, SCID, Mice, Transgenic, T-Lymphocytes, Regulatory
Added June 8, 2020
1 Communities
1 Members
0 Resources
16 MeSH Terms
Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms.
Yang J, Kumar A, Vilgelm AE, Chen SC, Ayers GD, Novitskiy SV, Joyce S, Richmond A
(2018) Cancer Immunol Res 6: 1186-1198
MeSH Terms: Animals, Bone Marrow Transplantation, Cell Line, Tumor, Cytotoxicity, Immunologic, Fas Ligand Protein, Interleukin-18, Killer Cells, Natural, Macrophages, Melanoma, Experimental, Mice, Inbred C57BL, Mice, Transgenic, Neutrophils, Receptors, CXCR4
Added December 20, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7-mediated Fas ligand cleavage from bronchial epithelial cells.
Wadsworth SJ, Atsuta R, McIntyre JO, Hackett TL, Singhera GK, Dorscheid DR
(2010) J Allergy Clin Immunol 126: 366-74, 374.e1-8
MeSH Terms: Asthma, Bronchi, Cell Line, Transformed, Epithelial Cells, Fas Ligand Protein, Gene Expression Regulation, Enzymologic, Humans, Interleukin-13, Interleukin-4, Interleukin-9, Matrix Metalloproteinase 2, Matrix Metalloproteinase 7, Matrix Metalloproteinase 9, Models, Biological, RNA, Small Interfering, Respiratory Mucosa, Th2 Cells, fas Receptor
Added May 9, 2014
1 Communities
0 Members
0 Resources
18 MeSH Terms
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression.
Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K
(2009) Cancer Res 69: 1080-8
MeSH Terms: Animals, Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein, Caspase 8, Caspase Inhibitors, Cell Line, Tumor, Enzyme Activation, Fas Ligand Protein, Humans, Immunohistochemistry, Interferon Regulatory Factors, Mice, Mitochondria, RNA, Messenger, RNA, Small Interfering, Receptors, TNF-Related Apoptosis-Inducing Ligand, Sarcoma, Sarcoma, Experimental, TNF-Related Apoptosis-Inducing Ligand
Added September 12, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.
Wax MB, Tezel G, Yang J, Peng G, Patil RV, Agarwal N, Sappington RM, Calkins DJ
(2008) J Neurosci 28: 12085-96
MeSH Terms: Animals, Animals, Newborn, Apoptosis, Autoantibodies, Autoimmune Diseases of the Nervous System, Autoimmunity, Cell Line, Fas Ligand Protein, Glaucoma, Heat-Shock Proteins, Intraocular Pressure, Lymphocyte Activation, Male, Microglia, Nerve Degeneration, Rats, Rats, Inbred Lew, Rats, Sprague-Dawley, Retinal Degeneration, Retinal Ganglion Cells, T-Lymphocytes, fas Receptor
Added May 28, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms
Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells.
Shimada M, Ando T, Peek RM, Watanabe O, Ishiguro K, Maeda O, Ishikawa D, Hasegawa M, Ina K, Ohmiya N, Niwa Y, Goto H
(2008) Eur J Gastroenterol Hepatol 20: 1144-50
MeSH Terms: Adult, Aged, Apoptosis, Caspase 1, Caspase 3, Cells, Cultured, Dyspepsia, Epithelial Cells, Fas Ligand Protein, Female, Gastric Mucosa, Helicobacter Infections, Helicobacter pylori, Humans, Interferon-gamma, Interleukin-18, Male, Middle Aged, Organ Culture Techniques, Stomach Ulcer, Up-Regulation
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Osteopontin regulates development and function of invariant natural killer T cells.
Diao H, Iwabuchi K, Li L, Onoe K, Van Kaer L, Kon S, Saito Y, Morimoto J, Denhardt DT, Rittling S, Uede T
(2008) Proc Natl Acad Sci U S A 105: 15884-9
MeSH Terms: Animals, Down-Regulation, Fas Ligand Protein, Interleukin-4, Killer Cells, Natural, Lymphocyte Activation, Mice, Mice, Knockout, Osteopontin, Receptors, KIR, Thymus Gland, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells.
Weinlich R, Bortoluci KR, Chehab CF, Serezani CH, Ulbrich AG, Peters-Golden M, Russo M, Amarante-Mendes GP
(2008) Cell Death Differ 15: 1901-9
MeSH Terms: Animals, CD3 Complex, Cell Death, Cyclic AMP-Dependent Protein Kinases, Cytoprotection, Dendritic Cells, Dinoprostone, Fas Ligand Protein, Guanine Nucleotide Exchange Factors, Lipopolysaccharides, Macrophage Activation, Macrophages, Mice, Myeloid Differentiation Factor 88, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Signal Transduction, Subcellular Fractions, T-Lymphocytes, Toll-Like Receptor 4, Up-Regulation
Added May 4, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
FLICE-like inhibitory protein blocks transforming growth factor beta 1-induced caspase activation and apoptosis in prostate epithelial cells.
Nastiuk KL, Yoo K, Lo K, Su K, Yeung P, Kutaka J, Danielpour D, Krolewski JJ
(2008) Mol Cancer Res 6: 231-42
MeSH Terms: Animals, Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein, Caspases, Cell Differentiation, Cell Line, Cell Survival, Enzyme Activation, Epithelial Cells, Etanercept, Fas Ligand Protein, Gene Expression Regulation, Humans, Immunoglobulin G, Insulin, Male, Mice, Prostate, RNA, Messenger, Rats, Receptors, TNF-Related Apoptosis-Inducing Ligand, Receptors, Tumor Necrosis Factor, Solubility, Transfection, Transforming Growth Factor beta1
Added April 7, 2010
0 Communities
1 Members
0 Resources
25 MeSH Terms
Loss of functional Fas ligand enhances intestinal tumorigenesis in the Min mouse model.
Fingleton B, Carter KJ, Matrisian LM
(2007) Cancer Res 67: 4800-6
MeSH Terms: Adenoma, Animals, Cell Movement, Cell Transformation, Neoplastic, Disease Models, Animal, Fas Ligand Protein, Genes, APC, Humans, Inflammation, Intestinal Neoplasms, Intestinal Polyps, Lymphocytes, Male, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Mutation
Added March 5, 2014
1 Communities
1 Members
0 Resources
17 MeSH Terms