Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 17

Publication Record

Connections

Primary prevention of venous thromboembolism with apixaban for multiple myeloma patients receiving immunomodulatory agents.
Cornell RF, Goldhaber SZ, Engelhardt BG, Moslehi J, Jagasia M, Harrell S, Rubinstein SM, Hall R, Wyatt H, Piazza G
(2020) Br J Haematol 190: 555-561
MeSH Terms: Aged, Comorbidity, Consolidation Chemotherapy, Factor Xa Inhibitors, Female, Hemorrhage, Humans, Immunologic Factors, Lenalidomide, Maintenance Chemotherapy, Male, Middle Aged, Multiple Myeloma, Myocardial Infarction, Pilot Projects, Proof of Concept Study, Prospective Studies, Pulmonary Embolism, Pyrazoles, Pyridones, Stroke, Thalidomide, Thrombophilia, Venous Thromboembolism, Venous Thrombosis
Added May 29, 2020
0 Communities
1 Members
0 Resources
25 MeSH Terms
Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor.
Puy C, Tucker EI, Matafonov A, Cheng Q, Zientek KD, Gailani D, Gruber A, McCarty OJ
(2015) Blood 125: 1488-96
MeSH Terms: Blood Coagulation, Blood Platelets, Blotting, Western, Cells, Cultured, Factor IX, Factor XIa, Factor Xa, Fibrin, Flow Cytometry, Human Umbilical Vein Endothelial Cells, Humans, Lipoproteins, Mutation, Recombinant Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Notecarin D binds human factor V and factor Va with high affinity in the absence of membranes.
Newell-Caito JL, Laha M, Tharp AC, Creamer JI, Xu H, Maddur AA, Tans G, Bock PE
(2011) J Biol Chem 286: 38286-38297
MeSH Terms: Anisotropy, Blood Coagulation, Catalytic Domain, Cell Membrane, Elapid Venoms, Factor V, Factor Va, Factor Xa, HEK293 Cells, Humans, Hydrolysis, Kinetics, Peptides, Phospholipids, Protein Binding
Added January 20, 2015
0 Communities
2 Members
0 Resources
15 MeSH Terms
Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.
Berny MA, Munnix IC, Auger JM, Schols SE, Cosemans JM, Panizzi P, Bock PE, Watson SP, McCarty OJ, Heemskerk JW
(2010) PLoS One 5: e10415
MeSH Terms: Animals, Blood Platelets, Calcium Signaling, Factor Xa, Fibrin, Fibrinogen, Humans, Mice, Perfusion, Phosphatidylserines, Platelet Aggregation, Protein Binding, Thrombin, Thromboplastin, Venous Thrombosis
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
The role of thrombin exosites I and II in the activation of human coagulation factor V.
Segers K, Dahlb├Ąck B, Bock PE, Tans G, Rosing J, Nicolaes GA
(2007) J Biol Chem 282: 33915-24
MeSH Terms: Arginine, Enzyme Activation, Factor V, Factor Xa, Humans, Protein Structure, Tertiary, Prothrombin, Serine Endopeptidases, Thrombin
Added January 20, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Restricted active site docking by enzyme-bound substrate enforces the ordered cleavage of prothrombin by prothrombinase.
Hacisalihoglu A, Panizzi P, Bock PE, Camire RM, Krishnaswamy S
(2007) J Biol Chem 282: 32974-82
MeSH Terms: Binding Sites, Factor Xa, Mutation, Prothrombin, Substrate Specificity, Thromboplastin
Added January 20, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
Activation of proteinase-activated receptor-2 in mesothelial cells induces pleural inflammation.
Lee YC, Knight DA, Lane KB, Cheng DS, Koay MA, Teixeira LR, Nesbitt JC, Chambers RC, Thompson PJ, Light RW
(2005) Am J Physiol Lung Cell Mol Physiol 288: L734-40
MeSH Terms: Animals, Biopsy, Chemokine CXCL2, Chemokines, Epithelium, Factor Xa, Humans, Inflammation, Male, Mice, Mice, Inbred C57BL, Neutrophils, Oligopeptides, Pleural Effusion, Receptor, PAR-2, Serine Endopeptidases, Trypsin, Tryptases
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Effects of activation peptide bond cleavage and fragment 2 interactions on the pathway of exosite I expression during activation of human prethrombin 1 to thrombin.
Anderson PJ, Nesset A, Bock PE
(2003) J Biol Chem 278: 44482-8
MeSH Terms: Arginine, Binding Sites, Enzyme Precursors, Factor Xa, Fluoresceins, Fluorescent Dyes, Hirudins, Humans, Peptide Fragments, Protein Conformation, Prothrombin, Spectrometry, Fluorescence, Thermodynamics, Threonine, Thrombin
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Comparative study of the active site caging of serine proteases: thrombin and factor Xa.
Thuring JW, Li H, Porter NA
(2002) Biochemistry 41: 2002-13
MeSH Terms: Acylation, Animals, Avidin, Biotin, Catalytic Domain, Cattle, Cinnamates, Factor Xa, Factor Xa Inhibitors, Humans, In Vitro Techniques, Kinetics, Molecular Structure, Photochemistry, Serine Endopeptidases, Serine Proteinase Inhibitors, Thrombin
Added May 29, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Role of proexosite I in factor Va-dependent substrate interactions of prothrombin activation.
Anderson PJ, Nesset A, Dharmawardana KR, Bock PE
(2000) J Biol Chem 275: 16435-42
MeSH Terms: Animals, Binding Sites, Cattle, Chromatography, Affinity, Enzyme Activation, Factor Va, Factor Xa, Humans, Kinetics, Protein Binding, Prothrombin, Sulfates
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms