Sexual Dimorphism in Stress-induced Hyperthermia in SNAP25Δ3 mice, a mouse model with disabled Gβγ regulation of the exocytotic fusion apparatus.
Thompson Gray AD, Simonetti J, Adegboye F, Jones CK, Zurawski Z, Hamm HE
(2020) Eur J Neurosci 52
: 2815-2826MeSH Terms: Animals, Disease Models, Animal, Exocytosis, Female, Hyperthermia, Male, Mice, Sex Characteristics, Spatial MemoryAdded May 26, 2020
9 MeSH Terms
Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes.
Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE
(2019) Sci Signal 12
: MeSH Terms: Animals, Calcium, Exocytosis, GTP-Binding Protein alpha Subunits, Gi-Go, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, Knockout, Neural Inhibition, Phenotype, Protein Binding, Receptors, G-Protein-Coupled, Synaptic Transmission, Synaptosomal-Associated Protein 25Added February 22, 2019
15 MeSH Terms
An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells.
Brindley RL, Bauer MB, Blakely RD, Currie KPM
(2016) Neuropharmacology 110
: 438-448MeSH Terms: Adrenal Glands, Animals, Calcium, Calcium Channels, N-Type, Cations, Divalent, Cells, Cultured, Chromaffin Cells, Exocytosis, Male, Membrane Potentials, Mice, Inbred C57BL, Mice, Knockout, Potassium Channels, Voltage-Gated, Receptors, Serotonin, Serotonin, Serotonin Agents, Serotonin Plasma Membrane Transport ProteinsAdded August 22, 2016
17 MeSH Terms
The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity.
Dooley J, Garcia-Perez JE, Sreenivasan J, Schlenner SM, Vangoitsenhoven R, Papadopoulou AS, Tian L, Schonefeldt S, Serneels L, Deroose C, Staats KA, Van der Schueren B, De Strooper B, McGuinness OP, Mathieu C, Liston A
(2016) Diabetes 65
: 53-61MeSH Terms: Animals, Blood Glucose, Diabetes Mellitus, Type 2, Exocytosis, Homeostasis, Insulin, Insulin Resistance, Insulin-Secreting Cells, Liver, Mice, Mice, Knockout, MicroRNAs, Obesity, Phosphatidylinositol 3-KinasesAdded March 28, 2016
14 MeSH Terms
Phosphatidylserine translocation at the yeast trans-Golgi network regulates protein sorting into exocytic vesicles.
Hankins HM, Sere YY, Diab NS, Menon AK, Graham TR
(2015) Mol Biol Cell 26
: 4674-85MeSH Terms: Adenosine Triphosphatases, Amino Acid Transport Systems, Basic, Calcium-Transporting ATPases, Cell Membrane, Exocytosis, Membrane Proteins, Mutation, Phosphatidylserines, Protein Transport, Proton-Translocating ATPases, Receptors, Steroid, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transport Vesicles, trans-Golgi NetworkAdded April 6, 2017
15 MeSH Terms
Exosome secretion is enhanced by invadopodia and drives invasive behavior.
Hoshino D, Kirkbride KC, Costello K, Clark ES, Sinha S, Grega-Larson N, Tyska MJ, Weaver AM
(2013) Cell Rep 5
: 1159-68MeSH Terms: Actins, Cell Line, Tumor, Cell Movement, Exocytosis, Exosomes, Humans, Pseudopodia, Secretory Pathway, Tetraspanin 30, rab GTP-Binding Proteins, rab27 GTP-Binding ProteinsAdded March 20, 2014
11 MeSH Terms
Signaling inputs to invadopodia and podosomes.
Hoshino D, Branch KM, Weaver AM
(2013) J Cell Sci 126
: 2979-89MeSH Terms: Actins, Animals, Cell Adhesion Molecules, Cell Movement, Cellular Microenvironment, Exocytosis, Extracellular Matrix, Humans, Intercellular Signaling Peptides and Proteins, Neoplasm Invasiveness, Phosphatidylinositol 3-Kinases, Pseudopodia, Signal TransductionAdded March 7, 2014
13 MeSH Terms
miR-153 regulates SNAP-25, synaptic transmission, and neuronal development.
Wei C, Thatcher EJ, Olena AF, Cha DJ, Perdigoto AL, Marshall AF, Carter BD, Broadie K, Patton JG
(2013) PLoS One 8
: e57080MeSH Terms: Animals, Base Sequence, Exocytosis, Green Fluorescent Proteins, MicroRNAs, Motor Neurons, Sequence Homology, Amino Acid, Signal Transduction, Synaptic Transmission, Synaptosomal-Associated Protein 25, ZebrafishAdded March 5, 2014
11 MeSH Terms
A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells.
Khandelwal P, Prakasam HS, Clayton DR, Ruiz WG, Gallo LI, van Roekel D, Lukianov S, Peränen J, Goldenring JR, Apodaca G
(2013) Mol Biol Cell 24
: 1007-19MeSH Terms: Actin Cytoskeleton, Animals, Exocytosis, Female, Green Fluorescent Proteins, Human Growth Hormone, Humans, Microscopy, Confocal, Microscopy, Electron, Myosins, Rats, Rats, Sprague-Dawley, Signal Transduction, Stress, Mechanical, Urinary Bladder, rab GTP-Binding ProteinsAdded September 3, 2013
16 MeSH Terms
Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25.
Wells CA, Zurawski Z, Betke KM, Yim YY, Hyde K, Rodriguez S, Alford S, Hamm HE
(2012) Mol Pharmacol 82
: 1136-49MeSH Terms: Alanine, Animals, Binding Sites, Botulinum Toxins, Calcium, Cell Line, Exocytosis, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Lampreys, Mutation, Neurons, Peptides, Protein Binding, Protein Interaction Domains and Motifs, Recombinant Fusion Proteins, SNARE Proteins, Sf9 Cells, Spodoptera, Synaptosomal-Associated Protein 25, Synaptotagmin I, Syntaxin 1Added December 10, 2013
22 MeSH Terms