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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC
(2017) J Clin Invest 127: 3835-3844
MeSH Terms: Adult, Aging, Animals, Calcineurin, Cyclin A1, Exenatide, Female, Forkhead Box Protein M1, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Male, Mice, Inbred NOD, Middle Aged, NFATC Transcription Factors, Peptides, Signal Transduction, Venoms
Added March 29, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The glucagon-like peptide-1 receptor in the ventromedial hypothalamus reduces short-term food intake in male mice by regulating nutrient sensor activity.
Burmeister MA, Brown JD, Ayala JE, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE
(2017) Am J Physiol Endocrinol Metab 313: E651-E662
MeSH Terms: Acetyl-CoA Carboxylase, Adenylate Kinase, Animals, Body Composition, CHO Cells, Cricetulus, Dose-Response Relationship, Drug, Eating, Exenatide, Food, Glucagon-Like Peptide-1 Receptor, Glycolysis, Homeostasis, Male, Mice, Mice, Inbred C57BL, Peptides, Sensation, TOR Serine-Threonine Kinases, Venoms, Ventromedial Hypothalamic Nucleus
Added October 23, 2017
0 Communities
1 Members
0 Resources
21 MeSH Terms
The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice.
Burmeister MA, Ayala JE, Smouse H, Landivar-Rocha A, Brown JD, Drucker DJ, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE
(2017) Diabetes 66: 372-384
MeSH Terms: Animals, Body Composition, Diet, High-Fat, Eating, Energy Metabolism, Exenatide, Gene Knockdown Techniques, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Glucose, Glucose Tolerance Test, Homeostasis, Hypothalamus, Incretins, Liraglutide, Male, Mice, Neurons, Paraventricular Hypothalamic Nucleus, Peptides, Pro-Opiomelanocortin, Venoms, Weight Gain
Added October 23, 2017
0 Communities
1 Members
0 Resources
23 MeSH Terms
Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.
Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC
(2016) Am J Physiol Endocrinol Metab 311: E859-E868
MeSH Terms: Activins, Adenosine, Adenosine A2 Receptor Agonists, Adenosine-5'-(N-ethylcarboxamide), Adult, Automation, Cell Culture Techniques, Cell Proliferation, Drug Evaluation, Preclinical, Erythropoietin, Exenatide, Female, GABA Agents, Harmine, Humans, Incretins, Insulin-Secreting Cells, Male, Middle Aged, Monoamine Oxidase Inhibitors, Myostatin, Nucleosides, Peptides, Platelet-Derived Growth Factor, Prolactin, Regeneration, Serotonin, Serotonin Receptor Agonists, Vasodilator Agents, Venoms, Young Adult, gamma-Aminobutyric Acid
Added April 26, 2017
0 Communities
2 Members
0 Resources
32 MeSH Terms
Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels.
Reddy IA, Pino JA, Weikop P, Osses N, Sørensen G, Bering T, Valle C, Bluett RJ, Erreger K, Wortwein G, Reyes JG, Graham D, Stanwood GD, Hackett TA, Patel S, Fink-Jensen A, Torres GE, Galli A
(2016) Transl Psychiatry 6: e809
MeSH Terms: Animals, Arachidonic Acid, Arachidonic Acids, Cocaine, Dopamine, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, Endocannabinoids, Exenatide, Glucagon-Like Peptide-1 Receptor, Glycerides, Homeostasis, Incretins, Mice, Microdialysis, Peptides, Proto-Oncogene Proteins c-fos, Septal Nuclei, Venoms
Added April 6, 2017
0 Communities
2 Members
0 Resources
19 MeSH Terms
Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM).
Morris LC, Nance KD, Gentry PR, Days EL, Weaver CD, Niswender CM, Thompson AD, Jones CK, Locuson CW, Morrison RD, Daniels JS, Niswender KD, Lindsley CW
(2014) J Med Chem 57: 10192-7
MeSH Terms: Allosteric Regulation, Animals, Catalepsy, Central Nervous System Agents, Drug Synergism, Exenatide, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Haloperidol, High-Throughput Screening Assays, Indoles, Insulin, Insulin Secretion, Islets of Langerhans, Male, Mice, Inbred C57BL, Microsomes, Liver, Peptides, Pyrrolidines, Receptors, Glucagon, Structure-Activity Relationship, Venoms
Added February 16, 2015
0 Communities
4 Members
0 Resources
22 MeSH Terms
A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors.
Morris LC, Days EL, Turney M, Mi D, Lindsley CW, Weaver CD, Niswender KD
(2014) J Biomol Screen 19: 847-58
MeSH Terms: Allosteric Regulation, Allosteric Site, Animals, Binding Sites, CHO Cells, Calcium, Cell Line, Cell Line, Tumor, Cricetinae, Cricetulus, Cyclic AMP, Disease Progression, Exenatide, Glucagon-Like Peptide 1, Glucose, High-Throughput Screening Assays, Humans, Liraglutide, Peptides, Receptors, Glucagon, Recombinant Proteins, Signal Transduction, Venoms
Added August 14, 2014
0 Communities
3 Members
0 Resources
23 MeSH Terms
Protection of glucagon-like peptide-1 in cisplatin-induced renal injury elucidates gut-kidney connection.
Katagiri D, Hamasaki Y, Doi K, Okamoto K, Negishi K, Nangaku M, Noiri E
(2013) J Am Soc Nephrol 24: 2034-43
MeSH Terms: Acute Kidney Injury, Animals, Antineoplastic Agents, Apoptosis, Cisplatin, Dipeptidyl-Peptidase IV Inhibitors, Exenatide, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Hypoglycemic Agents, Intestinal Mucosa, Male, Mice, Mice, Inbred C57BL, Oxidative Stress, Peptides, Piperidines, RNA, Small Interfering, Receptors, Glucagon, Reperfusion Injury, Uracil, Venoms
Added February 11, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Effects of intraportal exenatide on hepatic glucose metabolism in the conscious dog.
Edgerton DS, An Z, Johnson KM, Farmer T, Farmer B, Neal D, Cherrington AD
(2013) Am J Physiol Endocrinol Metab 305: E132-9
MeSH Terms: Animals, Consciousness, Dogs, Exenatide, Female, Glucose, Hyperglycemia, Hypoglycemic Agents, Infusions, Intravenous, Insulin, Lactic Acid, Liver, Male, Peptides, Portal Vein, Venoms
Added July 21, 2014
1 Communities
4 Members
1 Resources
16 MeSH Terms
β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion.
Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B
(2013) Diabetes 62: 1527-36
MeSH Terms: Animals, Crosses, Genetic, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Enzyme Induction, Exenatide, Glucose Clamp Technique, Hyperglycemia, Hypoglycemic Agents, Insulin, Insulin Secretion, Insulin-Secreting Cells, Kinetics, Mice, Mutant Proteins, Patch-Clamp Techniques, Peptides, Phosphorylation, Protein Processing, Post-Translational, Protein Subunits, Second Messenger Systems, Up-Regulation, Venoms
Added February 12, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms