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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 189

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ
(2021) Nat Commun 12: 5263
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Casein Kinase Ialpha, Drosophila Proteins, Drosophila melanogaster, Embryo, Nonmammalian, Evolution, Molecular, HEK293 Cells, Humans, Immunologic Factors, Lenalidomide, Mice, Organoids, Peptide Hydrolases, Ubiquitin-Protein Ligases, Ubiquitination, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins
Added September 11, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.
Lamb DC, Hargrove TY, Zhao B, Wawrzak Z, Goldstone JV, Nes WD, Kelly SL, Waterman MR, Stegeman JJ, Lepesheva GI
(2021) Mol Biol Evol 38: 952-967
MeSH Terms: Animals, Evolution, Molecular, Humans, Methylococcus capsulatus, Protein Conformation, Sterol 14-Demethylase
Added July 2, 2021
0 Communities
1 Members
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MeSH Terms
The Impact of Natural Selection on the Evolution and Function of Placentally Expressed Galectins.
Ely ZA, Moon JM, Sliwoski GR, Sangha AK, Shen XX, Labella AL, Meiler J, Capra JA, Rokas A
(2019) Genome Biol Evol 11: 2574-2592
MeSH Terms: Animals, Biological Evolution, Eutheria, Evolution, Molecular, Female, Galectins, Haplotypes, Humans, Models, Molecular, Phylogeny, Placenta, Polymorphism, Single Nucleotide, Pregnancy, Selection, Genetic
Added March 3, 2020
0 Communities
2 Members
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14 MeSH Terms
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function.
Benton ML, Talipineni SC, Kostka D, Capra JA
(2019) BMC Genomics 20: 511
MeSH Terms: Cell Line, Databases, Genetic, Enhancer Elements, Genetic, Evolution, Molecular, Gene Expression Regulation, Genomics, Humans, Liver, Molecular Sequence Annotation, Myocardium
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
Signatures of Recent Positive Selection in Enhancers Across 41 Human Tissues.
Moon JM, Capra JA, Abbot P, Rokas A
(2019) G3 (Bethesda) 9: 2761-2774
MeSH Terms: DNA Transposable Elements, Databases, Genetic, Enhancer Elements, Genetic, Evolution, Molecular, Genome-Wide Association Study, Genomics, Humans, Immunity, Organ Specificity, Quantitative Trait, Heritable, Selection, Genetic
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts.
Steenwyk JL, Opulente DA, Kominek J, Shen XX, Zhou X, Labella AL, Bradley NP, Eichman BF, Čadež N, Libkind D, DeVirgilio J, Hulfachor AB, Kurtzman CP, Hittinger CT, Rokas A
(2019) PLoS Biol 17: e3000255
MeSH Terms: Base Sequence, Cell Cycle, DNA Damage, DNA Repair, Evolution, Molecular, Genes, Fungal, Phenotype, Phylogeny, Saccharomycetales
Added August 26, 2019
0 Communities
1 Members
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9 MeSH Terms
Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway.
Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E
(2019) Mech Dev 156: 20-31
MeSH Terms: Animals, Body Patterning, Drosophila, Embryonic Development, Evolution, Molecular, Gene Expression Regulation, Developmental, Glycosylation, Humans, Phosphotransferases (Alcohol Group Acceptor), Wnt Signaling Pathway, Xenopus laevis, Zebrafish
Added April 10, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus.
Choby JE, Buechi HB, Farrand AJ, Skaar EP, Barber MF
(2018) mBio 9:
MeSH Terms: Animals, Cation Transport Proteins, Evolution, Molecular, Hemoglobins, Host-Pathogen Interactions, Iron, Mutation, Primates, Protein Binding, Species Specificity, Staphylococcus aureus
Added April 7, 2019
0 Communities
1 Members
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11 MeSH Terms
Unicellular ancestry and mechanisms of diversification of Goodpasture antigen-binding protein.
Darris C, Revert F, Revert-Ros F, Gozalbo-Rovira R, Feigley A, Fidler A, Lopez-Pascual E, Saus J, Hudson BG
(2019) J Biol Chem 294: 759-769
MeSH Terms: Basement Membrane, Evolution, Molecular, Humans, Isoenzymes, Protein-Serine-Threonine Kinases
Added November 19, 2018
0 Communities
1 Members
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5 MeSH Terms
Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties.
Chen L, Fish AE, Capra JA
(2018) PLoS Comput Biol 14: e1006484
MeSH Terms: Animals, Conserved Sequence, Enhancer Elements, Genetic, Evolution, Molecular, Genomics, Humans, Machine Learning, Mammals, Neural Networks, Computer, Sequence Alignment, Sequence Analysis, DNA, Support Vector Machine
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms