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Results: 1 to 10 of 82

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An autoimmune-based, paraneoplastic neurologic syndrome following checkpoint inhibition and concurrent radiotherapy for merkel cell carcinoma: case report.
Sherry AD, Bezzerides M, Khattab MH, Luo G, Ancell KK, Kirschner AN
(2020) Strahlenther Onkol 196: 664-670
MeSH Terms: Aged, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Immunological, Antineoplastic Combined Chemotherapy Protocols, Autoimmune Diseases of the Nervous System, Axilla, Carboplatin, Carcinoma, Merkel Cell, Combined Modality Therapy, Deglutition Disorders, Etoposide, Fatal Outcome, Fingers, Hallucinations, Humans, Lymphatic Metastasis, Male, Neuralgia, Palliative Care, Paraneoplastic Syndromes, Nervous System, Parenteral Nutrition, Total, Pneumonia, Aspiration, Positron Emission Tomography Computed Tomography, Radioimmunotherapy, Radiotherapy, High-Energy, Radiotherapy, Intensity-Modulated, Skin Neoplasms
Added March 3, 2020
0 Communities
1 Members
0 Resources
27 MeSH Terms
Cleavage of arrestin-3 by caspases attenuates cell death by precluding arrestin-dependent JNK activation.
Kook S, Vishnivetskiy SA, Gurevich VV, Gurevich EV
(2019) Cell Signal 54: 161-169
MeSH Terms: Animals, Apoptosis, Arrestins, COS Cells, Caspases, Chlorocebus aethiops, Etoposide, MAP Kinase Kinase 4, MAP Kinase Kinase Kinase 5
Added March 18, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Etoposide and cisplatin versus paclitaxel and carboplatin with concurrent thoracic radiotherapy in unresectable stage III non-small cell lung cancer: a multicenter randomized phase III trial.
Liang J, Bi N, Wu S, Chen M, Lv C, Zhao L, Shi A, Jiang W, Xu Y, Zhou Z, Wang W, Chen D, Hui Z, Lv J, Zhang H, Feng Q, Xiao Z, Wang X, Liu L, Zhang T, Du L, Chen W, Shyr Y, Yin W, Li J, He J, Wang L
(2017) Ann Oncol 28: 777-783
MeSH Terms: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Non-Small-Cell Lung, Chemoradiotherapy, Cisplatin, Etoposide, Female, Humans, Kaplan-Meier Estimate, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paclitaxel, Proportional Hazards Models
Added April 18, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
Carrillo AM, Hicks M, Khabele D, Eischen CM
(2015) Mol Cancer Res 13: 1197-205
MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cisplatin, Comet Assay, DNA Breaks, Double-Stranded, DNA Damage, DNA Repair, Etoposide, Female, Fibroblasts, HEK293 Cells, Humans, Imidazoles, Mice, Mice, Transgenic, Mutagens, Ovarian Neoplasms, Piperazines, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53
Added February 22, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Kook S, Zhan X, Cleghorn WM, Benovic JL, Gurevich VV, Gurevich EV
(2014) Cell Death Differ 21: 172-84
MeSH Terms: Animals, Apoptosis, Arrestins, BH3 Interacting Domain Death Agonist Protein, Caspase 3, Caspases, Cell Line, Cytochromes c, Etoposide, Mice, Mitochondria, Protein Binding, Protein Isoforms, Recombinant Proteins, Tumor Necrosis Factor-alpha
Added February 12, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Etoposide catechol is an oxidizable topoisomerase II poison.
Jacob DA, Gibson EG, Mercer SL, Deweese JE
(2013) Chem Res Toxicol 26: 1156-8
MeSH Terms: Catechols, Cytochrome P-450 CYP3A, DNA, DNA Breaks, Double-Stranded, DNA Topoisomerases, Type II, Etoposide, Humans, Oxidation-Reduction
Added January 4, 2016
1 Communities
1 Members
0 Resources
8 MeSH Terms
Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
Nifoussi SK, Vrana JA, Domina AM, De Biasio A, Gui J, Gregory MA, Hann SR, Craig RW
(2012) PLoS One 7: e47060
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Blotting, Western, CHO Cells, Cell Line, Tumor, Cisplatin, Cricetinae, Cytarabine, Drug Resistance, Neoplasm, Etoposide, Flow Cytometry, Glycogen Synthase Kinase 3, Humans, Myeloid Cell Leukemia Sequence 1 Protein, Phosphorylation, Protein Stability, Proto-Oncogene Proteins c-bcl-2, Threonine, Vinblastine
Added March 20, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xL.
Zhan Z, He K, Zhu D, Jiang D, Huang YH, Li Y, Sun C, Jin YH
(2012) PLoS One 7: e44923
MeSH Terms: Active Transport, Cell Nucleus, Apoptosis, Biocatalysis, Cell Cycle Proteins, Cell Nucleus, Cyclin A, Cyclin-Dependent Kinase 2, Etoposide, HeLa Cells, Humans, Mitochondria, Phosphorylation, RNA Interference, Serine, Signal Transduction, Topoisomerase II Inhibitors, Up-Regulation, bcl-X Protein
Added July 28, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Neuroendocrine carcinoma in an adolescent with hypercortisolemia.
Fagan EL, Slone JS, Shoemaker AH, Black J, Berlin J, E Engel M
(2012) J Pediatr Hematol Oncol 34: e117-9
MeSH Terms: Adolescent, Adrenalectomy, Adrenocortical Hyperfunction, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Neuroendocrine, Combined Modality Therapy, Etoposide, Humans, Male, Neoadjuvant Therapy, Tomography, X-Ray Computed
Added May 2, 2013
0 Communities
2 Members
0 Resources
12 MeSH Terms
Copy number polymorphisms and anticancer pharmacogenomics.
Gamazon ER, Huang RS, Dolan ME, Cox NJ
(2011) Genome Biol 12: R46
MeSH Terms: Antineoplastic Agents, Biomarkers, Pharmacological, Carboplatin, Cell Line, Tumor, Cisplatin, Daunorubicin, Etoposide, Gene Dosage, Gene Expression, Genetic Predisposition to Disease, Genetic Variation, Genome, Human, Genome-Wide Association Study, Humans, Inhibitory Concentration 50, Neoplasms, Oligonucleotide Array Sequence Analysis, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Topoisomerase II Inhibitors
Added February 22, 2016
0 Communities
2 Members
0 Resources
22 MeSH Terms