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AXL Mediates Esophageal Adenocarcinoma Cell Invasion through Regulation of Extracellular Acidification and Lysosome Trafficking.
Maacha S, Hong J, von Lersner A, Zijlstra A, Belkhiri A
(2018) Neoplasia 20: 1008-1022
MeSH Terms: Adenocarcinoma, Animals, Benzocycloheptenes, Biological Transport, Cathepsin B, Cell Line, Tumor, Chick Embryo, Chorioallantoic Membrane, Epithelial-Mesenchymal Transition, Esophageal Neoplasms, Gene Expression Regulation, Neoplastic, Humans, Hydrogen-Ion Concentration, Lactates, Lysosomes, Monocarboxylic Acid Transporters, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Symporters, Triazoles
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology.
Bartley AN, Washington MK, Colasacco C, Ventura CB, Ismaila N, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA
(2017) J Clin Oncol 35: 446-464
MeSH Terms: Adenocarcinoma, Algorithms, Biomarkers, Tumor, Esophageal Neoplasms, Esophagogastric Junction, Humans, Receptor, ErbB-2, Stomach Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas.
Peng D, Guo Y, Chen H, Zhao S, Washington K, Hu T, Shyr Y, El-Rifai W
(2017) Sci Rep 7: 40729
MeSH Terms: Adenocarcinoma, Cell Line, Tumor, Comparative Genomic Hybridization, Computational Biology, DNA Copy Number Variations, DNA Methylation, Epigenesis, Genetic, Epigenomics, Esophageal Neoplasms, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Gene Ontology, Gene Regulatory Networks, Genomics, Humans
Added April 18, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology.
Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA
(2016) Am J Clin Pathol 146: 647-669
MeSH Terms: Adenocarcinoma, Antineoplastic Agents, Clinical Decision-Making, Esophageal Neoplasms, Esophagogastric Junction, Genetic Testing, Humans, Medical Oncology, Receptor, ErbB-2, Stomach Neoplasms, United States
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Integrated genomic characterization of oesophageal carcinoma.
Cancer Genome Atlas Research Network, Analysis Working Group: Asan University, BC Cancer Agency, Brigham and Women’s Hospital, Broad Institute, Brown University, Case Western Reserve University, Dana-Farber Cancer Institute, Duke University, Greater Poland Cancer Centre, Harvard Medical School, Institute for Systems Biology, KU Leuven, Mayo Clinic, Memorial Sloan Kettering Cancer Center, National Cancer Institute, Nationwide Children’s Hospital, Stanford University, University of Alabama, University of Michigan, University of North Carolina, University of Pittsburgh, University of Rochester, University of Southern California, University of Texas MD Anderson Cancer Center, University of Washington, Van Andel Research Institute, Vanderbilt University, Washington University, Genome Sequencing Center: Broad Institute, Washington University in St. Louis, Genome Characterization Centers: BC Cancer Agency, Broad Institute, Harvard Medical School, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, University of North Carolina, University of Southern California Epigenome Center, University of Texas MD Anderson Cancer Center, Van Andel Research Institute, Genome Data Analysis Centers: Broad Institute, Brown University:, Harvard Medical School, Institute for Systems Biology, Memorial Sloan Kettering Cancer Center, University of California Santa Cruz, University of Texas MD Anderson Cancer Center, Biospecimen Core Resource: International Genomics Consortium, Research Institute at Nationwide Children’s Hospital, Tissue Source Sites: Analytic Biologic Services, Asan Medical Center, Asterand Bioscience, Barretos Cancer Hospital, BioreclamationIVT, Botkin Municipal Clinic, Chonnam National University Medical School, Christiana Care Health System, Cureline, Duke University, Emory University, Erasmus University, Indiana University School of Medicine, Institute of Oncology of Moldova, International Genomics Consortium, Invidumed, Israelitisches Krankenhaus Hamburg, Keimyung University School of Medicine, Memorial Sloan Kettering Cancer Center, National Cancer Center Goyang, Ontario Tumour Bank, Peter MacCallum Cancer Centre, Pusan National University Medical School, Ribeirão Preto Medical School, St. Joseph’s Hospital &Medical Center, St. Petersburg Academic University, Tayside Tissue Bank, University of Dundee, University of Kansas Medical Center, University of Michigan, University of North Carolina at Chapel Hill, University of Pittsburgh School of Medicine, University of Texas MD Anderson Cancer Center, Disease Working Group: Duke University, Memorial Sloan Kettering Cancer Center, National Cancer Institute, University of Texas MD Anderson Cancer Center, Yonsei University College of Medicine, Data Coordination Center: CSRA Inc., Project Team: National Institutes of Health
(2017) Nature 541: 169-175
MeSH Terms: Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms, Esophageal Squamous Cell Carcinoma, Genome, Human, Genomics, Humans, Molecular Targeted Therapy, Mutation, Stomach Neoplasms
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology.
Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA
(2016) Arch Pathol Lab Med 140: 1345-1363
MeSH Terms: Adenocarcinoma, Biomarkers, Tumor, Clinical Decision-Making, Combined Modality Therapy, Decision Trees, Diagnosis, Differential, Esophageal Neoplasms, Evidence-Based Medicine, Humans, Medical Oncology, Molecular Diagnostic Techniques, Molecular Targeted Therapy, Mutation, Neoplasm Grading, Neoplasm Staging, Pathology, Clinical, Receptor, ErbB-2, Societies, Medical, Stomach Neoplasms, United States
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Prevention of DNA damage in Barrett's esophageal cells exposed to acidic bile salts.
Bhardwaj V, Horvat A, Korolkova O, Washington MK, El-Rifai W, Dikalov SI, Zaika AI
(2016) Carcinogenesis 37: 1161-1169
MeSH Terms: Acetophenones, Acids, Adenocarcinoma, Antioxidants, BRCA1 Protein, Barrett Esophagus, Bile Acids and Salts, Cell Line, Tumor, DNA Damage, DNA Repair, Esophageal Neoplasms, Gastric Acid, Gastroesophageal Reflux, Humans, Reactive Oxygen Species
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
The Role of the Microbiome in Gastrointestinal Cancer.
Wroblewski LE, Peek RM, Coburn LA
(2016) Gastroenterol Clin North Am 45: 543-56
MeSH Terms: Adenocarcinoma, Animals, Carcinogenesis, Cell Proliferation, Colonic Polyps, Colorectal Neoplasms, Diet, Disease Models, Animal, Esophageal Neoplasms, Gastrointestinal Microbiome, Gastrointestinal Neoplasms, Gastrointestinal Tract, Helicobacter Infections, Helicobacter pylori, Humans, Inflammation, Microbiota, Stem Cells, Stomach Neoplasms
Added April 6, 2017
0 Communities
2 Members
0 Resources
19 MeSH Terms
Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis.
Qin HD, Liao XY, Chen YB, Huang SY, Xue WQ, Li FF, Ge XS, Liu DQ, Cai Q, Long J, Li XZ, Hu YZ, Zhang SD, Zhang LJ, Lehrman B, Scott AF, Lin D, Zeng YX, Shugart YY, Jia WH
(2016) Am J Hum Genet 98: 709-27
MeSH Terms: Adult, Aged, Aged, 80 and over, Animals, Carcinogenesis, Carcinoma, Squamous Cell, Carrier Proteins, Cell Cycle Proteins, Cell Line, Tumor, Cell Proliferation, DNA Copy Number Variations, Esophageal Neoplasms, Esophageal Squamous Cell Carcinoma, Exome, Fas-Associated Death Domain Protein, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genetic Association Studies, Humans, Male, Membrane Proteins, Mice, Mice, Inbred BALB C, MicroRNAs, Middle Aged, Mutation, Nerve Tissue Proteins, Prognosis, Selection, Genetic, Trans-Activators, Xenograft Model Antitumor Assays
Added April 3, 2018
0 Communities
1 Members
0 Resources
32 MeSH Terms
APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts.
Hong J, Chen Z, Peng D, Zaika A, Revetta F, Washington MK, Belkhiri A, El-Rifai W
(2016) Oncotarget 7: 16688-702
MeSH Terms: Adenocarcinoma, Barrett Esophagus, Bile Acids and Salts, Cell Line, Tumor, Cell Survival, DNA Damage, DNA Repair, DNA-(Apurinic or Apyrimidinic Site) Lyase, Esophageal Neoplasms, Gastroesophageal Reflux, Humans
Added April 8, 2016
0 Communities
3 Members
0 Resources
11 MeSH Terms