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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 17

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Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery.
Shuey MM, Billings FT, Wei S, Milne GL, Nian H, Yu C, Brown NJ
(2017) PLoS One 12: e0175292
MeSH Terms: Acute Kidney Injury, Aged, Cohort Studies, Coronary Artery Bypass, Eicosapentaenoic Acid, Epoxide Hydrolases, Female, Genotype, Glomerular Filtration Rate, Humans, Incidence, Lysine, Male, Middle Aged, Polymorphism, Genetic
Added November 7, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Genetic determinants of variability in warfarin response after the dose-titration phase.
Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM
(2016) Pharmacogenet Genomics 26: 510-516
MeSH Terms: Adult, African Americans, Aged, Aged, 80 and over, Anticoagulants, Calcium-Binding Proteins, Carbon-Carbon Ligases, Cytochrome P-450 CYP2C9, Cytochrome P450 Family 4, Epoxide Hydrolases, Female, Humans, International Normalized Ratio, Male, Middle Aged, Pharmacogenomic Variants, Vitamin K Epoxide Reductases, Warfarin, Whites
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans.
Ramirez CE, Shuey MM, Milne GL, Gilbert K, Hui N, Yu C, Luther JM, Brown NJ
(2014) Prostaglandins Other Lipid Mediat 113-115: 38-44
MeSH Terms: Adult, Arachidonic Acids, Body Mass Index, DNA, Epoxide Hydrolases, Female, Genetic Variation, Genotype, Glucose Clamp Technique, Humans, Insulin, Insulin Resistance, Insulin Secretion, Male, Middle Aged, Polymerase Chain Reaction, Statistics, Nonparametric, Young Adult
Added October 27, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.
Thomas CP, Boeglin WE, Garcia-Diaz Y, O'Donnell VB, Brash AR
(2013) Chem Phys Lipids 167-168: 21-32
MeSH Terms: Beta vulgaris, Chromatography, High Pressure Liquid, Epoxide Hydrolases, Epoxy Compounds, Gas Chromatography-Mass Spectrometry, Hemin, Hydrolysis, Intramolecular Oxidoreductases, Isomerism, Linoleic Acid, Magnetic Resonance Spectroscopy, Oleic Acids, Propanols, Stereoisomerism
Added March 7, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with forearm vasodilator responses in humans.
Lee CR, Pretorius M, Schuck RN, Burch LH, Bartlett J, Williams SM, Zeldin DC, Brown NJ
(2011) Hypertension 57: 116-22
MeSH Terms: Adult, Blacks, Blood Pressure, Bradykinin, Cohort Studies, Epoxide Hydrolases, Female, Forearm, Genetic Variation, Humans, Male, Methacholine Chloride, Nitroprusside, Smoking, Vascular Resistance, Vasodilation, Vasodilator Agents, Whites, Young Adult
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study.
Burdon KP, Lehtinen AB, Langefeld CD, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW
(2008) Diab Vasc Dis Res 5: 128-34
MeSH Terms: African Americans, Aged, Calcinosis, Carotid Artery Diseases, Coronary Artery Disease, Diabetes Mellitus, Type 2, Epoxide Hydrolases, Female, Gene Frequency, Genetic Predisposition to Disease, Humans, Male, Middle Aged, North Carolina, Phenotype, Polymorphism, Single Nucleotide, Risk Assessment, Whites
Added February 15, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Genetic architecture of transcript-level variation in humans.
Duan S, Huang RS, Zhang W, Bleibel WK, Roe CA, Clark TA, Chen TX, Schweitzer AC, Blume JE, Cox NJ, Dolan ME
(2008) Am J Hum Genet 82: 1101-13
MeSH Terms: Blacks, Cell Line, Computational Biology, Epoxide Hydrolases, Genetic Variation, Genome, Human, Haplotypes, Humans, Polymorphism, Single Nucleotide, Whites
Added February 22, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms
Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
Shimada T, Gillam EM, Oda Y, Tsumura F, Sutter TR, Guengerich FP, Inoue K
(1999) Chem Res Toxicol 12: 623-9
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Benzo(a)pyrene, Carcinogens, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1B1, Cytochrome P-450 Enzyme System, Dihydroxydihydrobenzopyrenes, Epoxide Hydrolases, Humans, Liver, Mutagenicity Tests, Rabbits, Rats, Recombinant Proteins, Salmonella typhimurium
Added May 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Kinetics of hydrolysis and reaction of aflatoxin B1 exo-8,9-epoxide and relevance to toxicity and detoxication.
Guengerich FP, Johnson WW
(1999) Drug Metab Rev 31: 141-58
MeSH Terms: Aflatoxin B1, Animals, Carcinogens, DNA, Epoxide Hydrolases, Epoxy Compounds, Glutathione, Humans, Hydrolysis, Inactivation, Metabolic, Kinetics
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Activation and detoxication of aflatoxin B1.
Guengerich FP, Johnson WW, Shimada T, Ueng YF, Yamazaki H, Langou√ęt S
(1998) Mutat Res 402: 121-8
MeSH Terms: Aflatoxin B1, Animals, Biotransformation, Carcinogens, Cytochrome P-450 Enzyme System, DNA, Epoxide Hydrolases, Humans, Inactivation, Metabolic
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms