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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity.
Zhang MZ, Wang S, Wang Y, Zhang Y, Ming Hao C, Harris RC
(2018) Hypertension 72: 1172-1179
MeSH Terms: Animals, Apoptosis, Aquaporin 2, Blood Pressure, Cyclooxygenase 2, Epithelial Sodium Channels, Hypertension, Kidney Medulla, Mice, Mice, Transgenic
Added November 8, 2018
1 Communities
0 Members
0 Resources
10 MeSH Terms
Functional features of the "finger" domain of the DEG/ENaC channels MEC-4 and UNC-8.
Matthewman C, Johnson CK, Miller DM, Bianchi L
(2018) Am J Physiol Cell Physiol 315: C155-C163
MeSH Terms: Amino Acid Sequence, Animals, Calcium, Cell Death, Cell Membrane Permeability, Epithelial Sodium Channels, Magnesium, Membrane Proteins, Mutation, Oocytes, Protein Transport, Sodium, Xenopus laevis
Added March 26, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension.
Barbaro NR, Foss JD, Kryshtal DO, Tsyba N, Kumaresan S, Xiao L, Mernaugh RL, Itani HA, Loperena R, Chen W, Dikalov S, Titze JM, Knollmann BC, Harrison DG, Kirabo A
(2017) Cell Rep 21: 1009-1020
MeSH Terms: Amiloride, Animals, Cells, Cultured, Cytokines, Dendritic Cells, Epithelial Sodium Channel Blockers, Epithelial Sodium Channels, Hypertension, Inflammation, Male, Mice, Mice, Inbred C57BL, NADPH Oxidases, Oxidative Stress, Prostaglandins E, Protein Kinase C, Sodium, Sodium-Hydrogen Exchanger 1, Superoxides
Added December 27, 2017
0 Communities
2 Members
0 Resources
19 MeSH Terms
Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Grimm PR, Coleman R, Delpire E, Welling PA
(2017) J Am Soc Nephrol 28: 2597-2606
MeSH Terms: Aldosterone, Animals, Blood Pressure, Epithelial Sodium Channels, Hydrochlorothiazide, Kidney Tubules, Distal, Mice, Natriuresis, Phosphorylation, Potassium, Potassium Channels, Inwardly Rectifying, Protein Serine-Threonine Kinases, Pseudohypoaldosteronism, Signal Transduction, Sodium Chloride Symporter Inhibitors, Solute Carrier Family 12, Member 3
Added May 3, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Inflammatory cytokines regulate renal sodium transporters: how, where, and why?
Norlander AE, Madhur MS
(2017) Am J Physiol Renal Physiol 313: F141-F144
MeSH Terms: Animals, Blood Pressure, Cytokines, Epithelial Cells, Epithelial Sodium Channels, Humans, Hypertension, Inflammation Mediators, Kidney, Membrane Transport Proteins, Renal Reabsorption, Signal Transduction, Sodium Chloride, Dietary
Added September 7, 2017
1 Communities
0 Members
0 Resources
13 MeSH Terms
Activation of the Endogenous Renin-Angiotensin-Aldosterone System or Aldosterone Administration Increases Urinary Exosomal Sodium Channel Excretion.
Qi Y, Wang X, Rose KL, MacDonald WH, Zhang B, Schey KL, Luther JM
(2016) J Am Soc Nephrol 27: 646-56
MeSH Terms: Adult, Aldosterone, Cross-Over Studies, Epithelial Sodium Channels, Exosomes, Female, Humans, Male, Renin-Angiotensin System, Sodium, Dietary
Added November 30, 2015
0 Communities
3 Members
0 Resources
10 MeSH Terms
Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50
MeSH Terms: Amiloride, Ammonia, Animals, Biological Transport, Blood Pressure, Carbonic Anhydrases, Chlorides, Disease Models, Animal, Enzyme Activation, Epithelial Sodium Channels, Gene Expression Profiling, Gene Regulatory Networks, Gitelman Syndrome, Ketoglutaric Acids, Kidney Glomerulus, Male, Mice, Mice, Knockout, Natriuresis, Nephrons, Paracrine Communication, Phosphorylation, Protein Processing, Post-Translational, Protein Serine-Threonine Kinases, Receptors, Notch, Receptors, Purinergic P2, Renal Reabsorption, Signal Transduction, Sodium Chloride, Sodium-Potassium-Chloride Symporters, Solute Carrier Family 12, Member 3
Added May 3, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.
Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA
(2015) Hypertension 65: 569-76
MeSH Terms: Angiotensin II, Animals, Biological Transport, Blood Pressure, Disease Models, Animal, Epithelial Sodium Channels, Genotype, Hypertension, Interferon-gamma, Interleukin-17, Kidney Tubules, Proximal, Mice, Mice, Inbred C57BL, Mice, Knockout, Sodium, Sodium Chloride Symporters, Sodium-Hydrogen Exchanger 3, Sodium-Hydrogen Exchangers, Solute Carrier Family 12, Member 1
Added March 31, 2015
2 Communities
2 Members
0 Resources
19 MeSH Terms
The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
Capdevila JH, Pidkovka N, Mei S, Gong Y, Falck JR, Imig JD, Harris RC, Wang W
(2014) J Biol Chem 289: 4377-86
MeSH Terms: Animals, Blood Pressure, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Epithelial Sodium Channels, Humans, Hypertension, Kidney, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 3, Phosphorylation, Sodium Chloride, Dietary
Added January 28, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms
Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism.
Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM
(2013) Am J Physiol Renal Physiol 304: F1390-7
MeSH Terms: Absorption, Aldosterone, Amiloride, Angiotensin II, Animals, Anion Transport Proteins, Chloride-Bicarbonate Antiporters, Chlorides, Epithelial Sodium Channels, Female, In Vitro Techniques, Kidney Tubules, Collecting, Male, Mice, Mice, Knockout, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Donors, Nitric Oxide Synthase, Sodium, Sulfate Transporters
Added March 31, 2015
1 Communities
2 Members
0 Resources
21 MeSH Terms