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Results: 1 to 8 of 8

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Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.
Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E
(2016) Infect Immun 84: 856-65
MeSH Terms: Animals, Bacterial Proteins, Bacterial Toxins, Clostridioides difficile, Enterocolitis, Pseudomembranous, Genotype, Glycosylation, Host-Pathogen Interactions, Humans, Male, Mice, Virulence, rhoA GTP-Binding Protein
Added April 4, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Reply to Planche et al.
Rao K, Young VB, Aronoff DM
(2015) Clin Infect Dis 61: 1211-2
MeSH Terms: Botulinum Toxins, Clostridioides difficile, Enterocolitis, Pseudomembranous, Feces, Female, Humans, Male, Ribotyping
Added June 2, 2017
0 Communities
1 Members
0 Resources
8 MeSH Terms
Cloning and variation of ground state intestinal stem cells.
Wang X, Yamamoto Y, Wilson LH, Zhang T, Howitt BE, Farrow MA, Kern F, Ning G, Hong Y, Khor CC, Chevalier B, Bertrand D, Wu L, Nagarajan N, Sylvester FA, Hyams JS, Devers T, Bronson R, Lacy DB, Ho KY, Crum CP, McKeon F, Xian W
(2015) Nature 522: 173-8
MeSH Terms: Bacterial Toxins, Cell Differentiation, Cell Lineage, Cells, Cultured, Clone Cells, Clostridioides difficile, Colon, Enterocolitis, Pseudomembranous, Epigenesis, Genetic, Epithelium, Fetus, Genomic Instability, Humans, Intestine, Small, Intestines, Organoids, Stem Cells
Added September 28, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Identification of toxemia in patients with Clostridium difficile infection.
Yu H, Chen K, Wu J, Yang Z, Shi L, Barlow LL, Aronoff DM, Garey KW, Savidge TC, von Rosenvinge EC, Kelly CP, Feng H
(2015) PLoS One 10: e0124235
MeSH Terms: Animals, Anti-Bacterial Agents, Antibodies, Bacterial, Antibodies, Neutralizing, Bacterial Proteins, Bacterial Toxins, Biological Assay, Blood Preservation, Chlorocebus aethiops, Clostridioides difficile, Diverticulitis, Colonic, Enterocolitis, Pseudomembranous, Enterotoxins, False Negative Reactions, Female, Glycosylation, Humans, Immunocompromised Host, Immunoglobulin G, Multiple Trauma, Protein Processing, Post-Translational, Protein Stability, Risk Factors, Toxemia, Vero Cells, Young Adult, rac1 GTP-Binding Protein
Added June 2, 2017
0 Communities
1 Members
0 Resources
27 MeSH Terms
Clostridium difficile ribotype 027: relationship to age, detectability of toxins A or B in stool with rapid testing, severe infection, and mortality.
Rao K, Micic D, Natarajan M, Winters S, Kiel MJ, Walk ST, Santhosh K, Mogle JA, Galecki AT, LeBar W, Higgins PD, Young VB, Aronoff DM
(2015) Clin Infect Dis 61: 233-41
MeSH Terms: Adult, Age Factors, Aged, Botulinum Toxins, Clostridioides difficile, Enterocolitis, Pseudomembranous, Feces, Female, Humans, Immunoenzyme Techniques, Male, Middle Aged, Models, Statistical, Odds Ratio, Polymerase Chain Reaction, ROC Curve, Ribotyping, Risk Factors, Severity of Illness Index
Added June 2, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Variation in germination of Clostridium difficile clinical isolates correlates to disease severity.
Carlson PE, Kaiser AM, McColm SA, Bauer JM, Young VB, Aronoff DM, Hanna PC
(2015) Anaerobe 33: 64-70
MeSH Terms: Clostridioides difficile, Enterocolitis, Pseudomembranous, Humans, Severity of Illness Index, Spores, Bacterial
Added June 2, 2017
0 Communities
1 Members
0 Resources
5 MeSH Terms
Postoperative burden of hospital-acquired Clostridium difficile infection.
Abdelsattar ZM, Krapohl G, Alrahmani L, Banerjee M, Krell RW, Wong SL, Campbell DA, Aronoff DM, Hendren S
(2015) Infect Control Hosp Epidemiol 36: 40-6
MeSH Terms: Academic Medical Centers, Adult, Age Factors, Aged, Amputation, Clostridioides difficile, Digestive System Surgical Procedures, Emergency Service, Hospital, Endocrine Surgical Procedures, Enterocolitis, Pseudomembranous, Female, Gynecologic Surgical Procedures, Hospitals, Community, Humans, Hypoalbuminemia, Immunosuppression, Incidence, Length of Stay, Lower Extremity, Male, Middle Aged, Patient Readmission, Postoperative Complications, Preoperative Period, Prospective Studies, Risk Factors, Sepsis
Added June 2, 2017
0 Communities
1 Members
0 Resources
27 MeSH Terms
Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism.
Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Haslam DB, Haslam D, Goldenring JR, Lacy DB
(2012) PLoS Pathog 8: e1003072
MeSH Terms: Animals, Bacterial Proteins, Bacterial Toxins, Caco-2 Cells, Clostridioides difficile, Enterocolitis, Pseudomembranous, Epithelial Cells, Female, HeLa Cells, Humans, Male, Mutation, Necrosis, Swine
Added September 3, 2013
0 Communities
3 Members
0 Resources
14 MeSH Terms