Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 6 of 6

Publication Record

Connections

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.
Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, Massion PP, Rudin CM, Poirier JT
(2017) Cancer Cell 31: 286-299
MeSH Terms: Animals, Drug Resistance, Neoplasm, Enhancer of Zeste Homolog 2 Protein, Humans, Lung Neoplasms, Mice, Nuclear Proteins, Small Cell Lung Carcinoma, Twist-Related Protein 1
Added January 29, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Lu W, Liu S, Li B, Xie Y, Izban MG, Ballard BR, Sathyanarayana SA, Adunyah SE, Matusik RJ, Chen Z
(2017) Oncogene 36: 1364-1373
MeSH Terms: Animals, Cell Line, Tumor, Disease Models, Animal, Enhancer of Zeste Homolog 2 Protein, Gene Knockout Techniques, Histones, Humans, Lysine, Male, Mice, PTEN Phosphohydrolase, Prostate, Prostatic Neoplasms, Protein Stability, S-Phase Kinase-Associated Proteins, TNF Receptor-Associated Factor 6, Tumor Suppressor Protein p53, Ubiquitination
Added April 18, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.
Nolan KD, Franco OE, Hance MW, Hayward SW, Isaacs JS
(2015) J Biol Chem 290: 8271-82
MeSH Terms: Animals, Antigens, CD, Cadherins, Cell Line, Tumor, Enhancer of Zeste Homolog 2 Protein, Epigenesis, Genetic, Epithelial-Mesenchymal Transition, Gene Expression, Gene Expression Regulation, Neoplastic, HEK293 Cells, HSP90 Heat-Shock Proteins, Humans, MAP Kinase Signaling System, Male, Mice, SCID, Neoplasm Invasiveness, Neoplasm Transplantation, Polycomb Repressive Complex 2, Polycomb-Group Proteins, Prostatic Neoplasms, Tumor Burden
Added February 19, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells.
Koumangoye RB, Andl T, Taubenslag KJ, Zilberman ST, Taylor CJ, Loomans HA, Andl CD
(2015) Mol Cancer 14: 24
MeSH Terms: 3' Untranslated Regions, Base Sequence, Binding Sites, Cell Line, Tumor, Down-Regulation, Enhancer of Zeste Homolog 2 Protein, Epigenesis, Genetic, Esophageal Neoplasms, Gene Expression Regulation, Neoplastic, Histone Deacetylases, Humans, MicroRNAs, Neoplasm Invasiveness, Polycomb Repressive Complex 2, Protein Binding, RNA Interference, Repressor Proteins, SOXC Transcription Factors
Added October 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming.
Tiwari N, Tiwari VK, Waldmeier L, Balwierz PJ, Arnold P, Pachkov M, Meyer-Schaller N, Schübeler D, van Nimwegen E, Christofori G
(2013) Cancer Cell 23: 768-83
MeSH Terms: Animals, Cell Line, Cell Movement, Cell Survival, Enhancer of Zeste Homolog 2 Protein, Epigenesis, Genetic, Epithelial-Mesenchymal Transition, Female, Gene Expression Regulation, Neoplastic, Histones, Humans, MCF-7 Cells, Mammary Neoplasms, Experimental, Methylation, Mice, Neoplasm Metastasis, Polycomb Repressive Complex 2, Promoter Regions, Genetic, SOXC Transcription Factors, Transcription, Genetic
Added August 9, 2013
1 Communities
0 Members
0 Resources
20 MeSH Terms
SMARCB1 protein and mRNA loss is not caused by promoter and histone hypermethylation in epithelioid sarcoma.
Papp G, Changchien YC, Péterfia B, Pecsenka L, Krausz T, Stricker TP, Khoor A, Donner L, Sápi Z
(2013) Mod Pathol 26: 393-403
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Child, Chromosomal Proteins, Non-Histone, DNA Methylation, DNA Mutational Analysis, DNA-Binding Proteins, Down-Regulation, Enhancer of Zeste Homolog 2 Protein, Female, Gene Deletion, Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease, Histones, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Laser Capture Microdissection, Male, Middle Aged, Mutation, Phenotype, Poland, Polycomb Repressive Complex 2, Promoter Regions, Genetic, RNA, Messenger, Real-Time Polymerase Chain Reaction, Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction, SMARCB1 Protein, Sarcoma, Soft Tissue Neoplasms, Transcription Factors, United States, Young Adult
Added March 28, 2014
0 Communities
1 Members
0 Resources
37 MeSH Terms