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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 130

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Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function.
Benton ML, Talipineni SC, Kostka D, Capra JA
(2019) BMC Genomics 20: 511
MeSH Terms: Cell Line, Databases, Genetic, Enhancer Elements, Genetic, Evolution, Molecular, Gene Expression Regulation, Genomics, Humans, Liver, Molecular Sequence Annotation, Myocardium
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
Signatures of Recent Positive Selection in Enhancers Across 41 Human Tissues.
Moon JM, Capra JA, Abbot P, Rokas A
(2019) G3 (Bethesda) 9: 2761-2774
MeSH Terms: DNA Transposable Elements, Databases, Genetic, Enhancer Elements, Genetic, Evolution, Molecular, Genome-Wide Association Study, Genomics, Humans, Immunity, Organ Specificity, Quantitative Trait, Heritable, Selection, Genetic
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
Sequence Characteristics Distinguish Transcribed Enhancers from Promoters and Predict Their Breadth of Activity.
Colbran LL, Chen L, Capra JA
(2019) Genetics 211: 1205-1217
MeSH Terms: Base Composition, Enhancer Elements, Genetic, Histone Code, Humans, Models, Genetic, Promoter Regions, Genetic, Support Vector Machine, Transcription Factors, Transcriptional Activation
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genome-wide maps of distal gene regulatory enhancers active in the human placenta.
Zhang J, Simonti CN, Capra JA
(2018) PLoS One 13: e0209611
MeSH Terms: Chromosome Mapping, Computational Biology, Enhancer Elements, Genetic, Female, Genes, Regulator, Genome-Wide Association Study, Genomics, Humans, Machine Learning, Molecular Sequence Annotation, Placenta, Pregnancy, ROC Curve
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties.
Chen L, Fish AE, Capra JA
(2018) PLoS Comput Biol 14: e1006484
MeSH Terms: Animals, Conserved Sequence, Enhancer Elements, Genetic, Evolution, Molecular, Genomics, Humans, Machine Learning, Mammals, Neural Networks, Computer, Sequence Alignment, Sequence Analysis, DNA, Support Vector Machine
Added March 3, 2020
0 Communities
1 Members
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MeSH Terms
A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.
Chen H, Li C, Peng X, Zhou Z, Weinstein JN, Cancer Genome Atlas Research Network, Liang H
(2018) Cell 173: 386-399.e12
MeSH Terms: Aneuploidy, B7-H1 Antigen, Chromatin, Databases, Genetic, Enhancer Elements, Genetic, Gene Expression Regulation, Neoplastic, Humans, Immunotherapy, Neoplasms, Sequence Analysis, RNA, Survival Rate
Added October 30, 2019
0 Communities
1 Members
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MeSH Terms
Gene Regulatory Enhancers with Evolutionarily Conserved Activity Are More Pleiotropic than Those with Species-Specific Activity.
Fish A, Chen L, Capra JA
(2017) Genome Biol Evol 9: 2615-2625
MeSH Terms: Animals, Callithrix, Cats, Cattle, Conserved Sequence, Databases, Genetic, Dogs, Enhancer Elements, Genetic, Evolution, Molecular, Genetic Pleiotropy, Histones, Humans, Macaca mulatta, Mice, Rabbits, Rats, Swine
Added March 14, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Short DNA sequence patterns accurately identify broadly active human enhancers.
Colbran LL, Chen L, Capra JA
(2017) BMC Genomics 18: 536
MeSH Terms: Animals, DNA, Drosophila melanogaster, Enhancer Elements, Genetic, GC Rich Sequence, Humans, Nucleotide Motifs, Sequence Analysis, DNA, Transcription Factors
Added March 14, 2018
0 Communities
1 Members
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9 MeSH Terms
The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.
Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, Kim JW
(2017) Elife 6:
MeSH Terms: Adaptation, Ocular, Animals, Cytoskeletal Proteins, DNA-Binding Proteins, Enhancer Elements, Genetic, Gene Expression Regulation, LIM Domain Proteins, LIM-Homeodomain Proteins, Mice, Mice, Knockout, PAX6 Transcription Factor, Retina, Transcription Factors
Added February 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Yang YP, Magnuson MA, Stein R, Wright CV
(2017) Development 144: 248-257
MeSH Terms: Animals, Binding Sites, Cell Differentiation, Embryo, Mammalian, Enhancer Elements, Genetic, Gene Expression Regulation, Developmental, Homeodomain Proteins, Insulin-Secreting Cells, Islets of Langerhans, Mammals, Mice, Mice, Transgenic, Organogenesis, Species Specificity, Trans-Activators
Added December 29, 2016
2 Communities
3 Members
0 Resources
15 MeSH Terms