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Results: 1 to 8 of 8

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Toward Precision Medicine in Pulmonary Arterial Hypertension.
Austin ED, Loyd JE
(2015) Am J Respir Crit Care Med 192: 1272-4
MeSH Terms: Antihypertensive Agents, Endothelin Receptor Antagonists, Endothelin-1, Female, Humans, Hypertension, Pulmonary, Male, Polymorphism, Single Nucleotide
Added February 21, 2017
0 Communities
1 Members
0 Resources
8 MeSH Terms
Parenteral Prostanoid Use at a Tertiary Referral Center: A Retrospective Cohort Study.
Hay BR, Pugh ME, Robbins IM, Hemnes AR
(2016) Chest 149: 660-6
MeSH Terms: Adult, Cause of Death, Cohort Studies, Comorbidity, Connective Tissue Diseases, Death, Sudden, Endothelin Receptor Antagonists, Familial Primary Pulmonary Hypertension, Female, Guideline Adherence, HIV Infections, Heart Defects, Congenital, Heart Failure, Humans, Hypertension, Pulmonary, Infusions, Parenteral, Male, Middle Aged, Patient Selection, Phosphodiesterase 5 Inhibitors, Practice Guidelines as Topic, Prostaglandins, Quality Improvement, Retrospective Studies, Severity of Illness Index, Tertiary Care Centers
Added March 8, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Combination therapy in pulmonary arterial hypertension.
Pugh ME, Hemnes AR, Robbins IM
(2013) Clin Chest Med 34: 841-55
MeSH Terms: Drug Therapy, Combination, Endothelin Receptor Antagonists, Epoprostenol, Familial Primary Pulmonary Hypertension, Humans, Hypertension, Pulmonary, Phosphodiesterase 5 Inhibitors, Prostaglandins
Added March 8, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Safety of sapropterin dihydrochloride (6r-bh4) in patients with pulmonary hypertension.
Robbins IM, Hemnes AR, Gibbs JS, Christman BW, Howard L, Meehan S, Cabrita I, Gonzalez R, Oyler T, Zhao L, Du RH, Mendes LA, Wilkins MR
(2011) Exp Lung Res 37: 26-34
MeSH Terms: Administration, Oral, Adult, Antihypertensive Agents, Biomarkers, Biopterin, Chemokine CCL2, Drug Therapy, Combination, Endothelin Receptor Antagonists, Exercise Test, Exercise Tolerance, Female, Humans, Hypertension, Pulmonary, London, Male, Middle Aged, Natriuretic Peptide, Brain, Nitric Oxide, Oxidative Stress, Peptide Fragments, Phosphodiesterase 5 Inhibitors, Piperazines, Purines, Recovery of Function, Sildenafil Citrate, Sulfones, Tennessee, Time Factors, Treatment Outcome, Walking
Added February 19, 2015
0 Communities
2 Members
0 Resources
30 MeSH Terms
Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat.
Saleh MA, Boesen EI, Pollock JS, Savin VJ, Pollock DM
(2010) Hypertension 56: 942-9
MeSH Terms: Analysis of Variance, Animals, Atrasentan, Blood Pressure, Endothelin Receptor Antagonists, Endothelin-1, Immunoassay, Immunohistochemistry, Inflammation, Kidney Glomerulus, Male, Permeability, Pyrrolidines, Rats, Rats, Sprague-Dawley, Receptors, Endothelin
Added July 31, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Endothelin A receptor mediates functional but not structural damage in chronic cyclosporine nephrotoxicity.
Hunley TE, Fogo A, Iwasaki S, Kon V
(1995) J Am Soc Nephrol 5: 1718-23
MeSH Terms: Animals, Cyclosporine, Endothelin Receptor Antagonists, Kidney, Male, Peptides, Cyclic, Rats, Rats, Wistar, Receptors, Endothelin, Time Factors
Added February 25, 2014
1 Communities
2 Members
0 Resources
10 MeSH Terms
Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Studies in chronic cyclosporine nephrotoxicity in rats.
Kon V, Hunley TE, Fogo A
(1995) Transplantation 60: 89-95
MeSH Terms: Angiotensin II, Animals, Cyclosporine, Endothelin Receptor Antagonists, Endothelins, Fibrosis, Kidney Function Tests, Kidney Glomerulus, Male, Rats, Rats, Wistar, Receptor, Endothelin A, Receptor, Endothelin B, Signal Transduction, Vasoconstriction
Added February 25, 2014
1 Communities
2 Members
0 Resources
15 MeSH Terms
Endothelin receptor antagonism is protective in in vivo acute cyclosporine toxicity.
Fogo A, Hellings SE, Inagami T, Kon V
(1992) Kidney Int 42: 770-4
MeSH Terms: Acute Disease, Animals, Cyclosporine, Endothelin Receptor Antagonists, Injections, Injections, Intra-Arterial, Injections, Intravenous, Kidney, Kidney Diseases, Male, Rats, Rats, Wistar, Renal Artery
Added January 20, 2012
1 Communities
1 Members
0 Resources
13 MeSH Terms