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CD36 maintains the gastric mucosa and associates with gastric disease.
Jacome-Sosa M, Miao ZF, Peche VS, Morris EF, Narendran R, Pietka KM, Samovski D, Lo HG, Pietka T, Varro A, Love-Gregory L, Goldenring JR, Kuda O, Gamazon ER, Mills JC, Abumrad NA
(2021) Commun Biol 4: 1247
MeSH Terms: Animals, CD36 Antigens, Endothelial Cells, Female, Gastric Mucosa, Gastritis, Gastrointestinal Hemorrhage, Male, Mice, Mice, Inbred C57BL, Stomach Ulcer
Added November 24, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.
Miller MR, Koch SR, Choi H, Lamb FS, Stark RJ
(2021) Transl Res 235: 115-128
MeSH Terms: Cells, Cultured, Cytokines, Endothelial Cells, Humans, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Nitric Oxide Synthase Type III, Permeability, Toll-Like Receptor 4, p38 Mitogen-Activated Protein Kinases
Added April 16, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
Bersini S, Arrojo E Drigo R, Huang L, Shokhirev MN, Hetzer MW
(2020) Adv Biosyst 4: e2000044
MeSH Terms: Aged, Aging, Alzheimer Disease, Endothelial Cells, Female, Fibroblasts, Humans, Male, Microfluidic Analytical Techniques, Microvessels
Added April 14, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.
Meegan JE, Shaver CM, Putz ND, Jesse JJ, Landstreet SR, Lee HNR, Sidorova TN, McNeil JB, Wynn JL, Cheung-Flynn J, Komalavilas P, Brophy CM, Ware LB, Bastarache JA
(2020) PLoS One 15: e0228727
MeSH Terms: Animals, Apoptosis, Capillary Permeability, Endothelial Cells, Female, Hemoglobins, Humans, Inflammation, Lung, Mice, Mice, Inbred C57BL, Oxidative Stress, Sepsis
Added March 3, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
The peroxisome proliferator-activated receptor-β/δ antagonist GSK0660 mitigates retinal cell inflammation and leukostasis.
Capozzi ME, Savage SR, McCollum GW, Hammer SS, Ramos CJ, Yang R, Bretz CA, Penn JS
(2020) Exp Eye Res 190: 107885
MeSH Terms: Adult, Animals, Cells, Cultured, Cytokines, Endothelial Cells, Ependymoglial Cells, Humans, Inflammation, Leukostasis, Male, Mice, Mice, Inbred C57BL, PPAR delta, PPAR-beta, Palmitic Acids, Real-Time Polymerase Chain Reaction, Retina, Retinitis, Sulfones, Thiophenes
Added March 30, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways.
Cheung-Flynn J, Alvis BD, Hocking KM, Guth CM, Luo W, McCallister R, Chadalavada K, Polcz M, Komalavilas P, Brophy CM
(2019) PLoS One 14: e0220893
MeSH Terms: Adenosine Triphosphate, Animals, Aorta, Cell Membrane, Endothelial Cells, Humans, Inflammation, Intracellular Signaling Peptides and Proteins, Phosphorylation, Protein Serine-Threonine Kinases, Rats, Receptors, Purinergic P2X7, Saline Solution, Saphenous Vein, Signal Transduction, Swine, p38 Mitogen-Activated Protein Kinases
Added March 3, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Loss of flow responsive Tie1 results in Impaired
Aortic valve remodeling.
Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS
(2019) Dev Biol 455: 73-84
MeSH Terms: Animals, Aortic Valve, Endothelial Cells, Extracellular Matrix, Female, Gene Expression Profiling, Gene Expression Regulation, Developmental, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Organogenesis, Pregnancy, Receptor, TIE-1, SOX9 Transcription Factor, Vascular Remodeling
Added November 25, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing.
Saraswati S, Marrow SMW, Watch LA, Young PP
(2019) Nat Commun 10: 3027
MeSH Terms: Actins, Animals, Bone Marrow Transplantation, Calcium-Binding Proteins, Cell Differentiation, Disease Models, Animal, Fibroblasts, Fibrosis, Green Fluorescent Proteins, Human Umbilical Vein Endothelial Cells, Humans, Mice, Mice, Inbred C57BL, Mice, Transgenic, Myocardial Infarction, Myocardium, Neovascularization, Physiologic, S100 Calcium-Binding Protein A4, Transplantation Chimera, Wound Healing
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Age Mosaicism across Multiple Scales in Adult Tissues.
Arrojo E Drigo R, Lev-Ram V, Tyagi S, Ramachandra R, Deerinck T, Bushong E, Phan S, Orphan V, Lechene C, Ellisman MH, Hetzer MW
(2019) Cell Metab 30: 343-351.e3
MeSH Terms: Aging, Animals, Cellular Senescence, Cilia, Endothelial Cells, Female, Fibroblasts, Insulin-Secreting Cells, Liver, Mice, Mice, Inbred Strains, Mosaicism, Neurons, Organ Specificity, Pancreas
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds.
Faley SL, Neal EH, Wang JX, Bosworth AM, Weber CM, Balotin KM, Lippmann ES, Bellan LM
(2019) Stem Cell Reports 12: 474-487
MeSH Terms: Albumins, Blood-Brain Barrier, Brain, Cells, Cultured, Dextrans, Endothelial Cells, Endothelium, Fluorescein, Humans, Hydrogels, Induced Pluripotent Stem Cells, Microvessels
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms