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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 31

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Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
Plate L, Rius B, Nguyen B, Genereux JC, Kelly JW, Wiseman RL
(2019) Cell Chem Biol 26: 913-925.e4
MeSH Terms: Activating Transcription Factor 6, Amyloidogenic Proteins, Amyloidosis, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Molecular Chaperones, Proteomics, Transcription Factors, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.
Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW
(2018) Elife 7:
MeSH Terms: Activating Transcription Factor 6, Amides, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Phenylpropionates, Prodrugs, Signal Transduction, Small Molecule Libraries, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The unfolded protein response regulator ATF6 promotes mesodermal differentiation.
Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH
(2018) Sci Signal 11:
MeSH Terms: Activating Transcription Factor 6, Animals, Cell Differentiation, Cell Line, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, Gene Expression, Humans, Induced Pluripotent Stem Cells, Mesoderm, Mutation, Signal Transduction, Small Molecule Libraries, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.
Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J
(2018) Sci Adv 4: e1701393
MeSH Terms: Amino Acid Sequence, Bacteriophages, Biocatalysis, Cyclin-Dependent Kinase 4, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Mutant Proteins, Mutation, Peptides, Proteolysis, Reproducibility of Results, Signal Transduction, Substrate Specificity, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Ubiquitin, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases, Ubiquitination
Added March 24, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.
Kropski JA, Blackwell TS
(2018) J Clin Invest 128: 64-73
MeSH Terms: Animals, Apoptosis, Endoplasmic Reticulum Stress, Fibrosis, Humans, Inflammation, Macrophages, Molecular Chaperones, Myofibroblasts, Signal Transduction, Unfolded Protein Response
Added March 21, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to Therapy.
Plate L, Wiseman RL
(2017) Trends Cell Biol 27: 722-737
MeSH Terms: Activating Transcription Factor 6, Animals, Biological Transport, Endoplasmic Reticulum Stress, Humans, Proteome, Proteostasis, Repressor Proteins, Secretory Pathway, Signal Transduction, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis.
Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG
(2016) Circ J 80: 2259-2268
MeSH Terms: Animals, Atherosclerosis, Endoplasmic Reticulum Stress, Humans, I-kappa B Kinase, Isoenzymes, Macrophages, Mechanistic Target of Rapamycin Complex 2, Mitogen-Activated Protein Kinase 8, Multiprotein Complexes, Proto-Oncogene Proteins c-akt, Signal Transduction, TOR Serine-Threonine Kinases, Unfolded Protein Response
Added April 10, 2018
0 Communities
1 Members
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MeSH Terms
NOD1 and NOD2: New Functions Linking Endoplasmic Reticulum Stress and Inflammation.
Byndloss MX, Keestra-Gounder AM, Bäumler AJ, Tsolis RM
(2016) DNA Cell Biol 35: 311-3
MeSH Terms: Animals, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, Humans, Immunity, Innate, Inflammation, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.
Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF
(2016) Arterioscler Thromb Vasc Biol 36: 1122-31
MeSH Terms: Animals, Aorta, Aortic Diseases, Apoptosis, Atherosclerosis, Bone Marrow Cells, Bone Marrow Transplantation, Cell Survival, Cells, Cultured, Diet, High-Fat, Disease Models, Animal, Endoplasmic Reticulum Stress, Genetic Predisposition to Disease, Hypercholesterolemia, Macrophages, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinase 8, Mitogen-Activated Protein Kinase 9, PTEN Phosphohydrolase, Phenotype, Plaque, Atherosclerotic, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Receptors, LDL, Signal Transduction, bcl-Associated Death Protein
Added April 10, 2018
0 Communities
1 Members
0 Resources
MeSH Terms