Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 8 of 8

Publication Record

Connections

Depletion of the C. elegans NAC engages the unfolded protein response, resulting in increased chaperone expression and apoptosis.
Arsenovic PT, Maldonado AT, Colleluori VD, Bloss TA
(2012) PLoS One 7: e44038
MeSH Terms: Animals, Caenorhabditis elegans, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Gene Expression Regulation, Developmental, Heat-Shock Proteins, Hot Temperature, Intestinal Mucosa, Lysosomes, Molecular Chaperones, RNA Interference, Stress, Physiological, Unfolded Protein Response, Up-Regulation
Added April 25, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells.
Sato Y, Hatta M, Karim MF, Sawa T, Wei FY, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, Yamagata K
(2012) J Biol Chem 287: 23236-45
MeSH Terms: Animals, Apoptosis, Carrier Proteins, Cell Line, Tumor, Diabetes Mellitus, Type 2, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Endoplasmic Reticulum Stress, Female, Gene Expression Profiling, Heat-Shock Proteins, Insulin-Secreting Cells, Insulinoma, Intracellular Signaling Peptides and Proteins, Mice, Mice, Knockout, Pancreatic Neoplasms, Proteomics, Transcriptional Activation
Added June 22, 2012
1 Communities
1 Members
0 Resources
19 MeSH Terms
Phosphatidylethanolamines modified by γ-ketoaldehyde (γKA) induce endoplasmic reticulum stress and endothelial activation.
Guo L, Chen Z, Cox BE, Amarnath V, Epand RF, Epand RM, Davies SS
(2011) J Biol Chem 286: 18170-80
MeSH Terms: Cell Adhesion Molecules, Cell Line, Cell Membrane, Chemokine CCL2, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Endothelial Cells, Heat-Shock Proteins, Humans, Interleukin-8, Lipid Bilayers, Lipid Peroxidation, Phosphatidylethanolamines, Transcription Factor CHOP, Unfolded Protein Response
Added June 1, 2013
1 Communities
1 Members
0 Resources
15 MeSH Terms
Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.
Sun J, Wan C, Jia P, Fanous AH, Kendler KS, Riley BP, Zhao Z
(2011) Schizophr Res 125: 201-8
MeSH Terms: Alleles, Case-Control Studies, Endoplasmic Reticulum Chaperone BiP, Female, GRB2 Adaptor Protein, Gene Frequency, Genetic Predisposition to Disease, Genetics, Population, Genome-Wide Association Study, Genotype, Haplotypes, Humans, Ireland, Male, Northern Ireland, Polymorphism, Single Nucleotide, Psychotic Disorders, Risk Factors, Schizophrenia, Schizophrenic Psychology, Systems Biology
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.
Passarella RJ, Spratt DE, van der Ende AE, Phillips JG, Wu H, Sathiyakumar V, Zhou L, Hallahan DE, Harth E, Diaz R
(2010) Cancer Res 70: 4550-9
MeSH Terms: Animals, Antineoplastic Agents, Phytogenic, Apoptosis, Bacteriophages, Breast Neoplasms, Cell Growth Processes, Cell Line, Tumor, Coculture Techniques, Delayed-Action Preparations, Drug Delivery Systems, Endoplasmic Reticulum Chaperone BiP, Endothelial Cells, Glioma, Heat-Shock Proteins, Humans, Mice, Mice, Inbred C57BL, Mice, Nude, Nanoparticles, Oligopeptides, Paclitaxel, Recombinant Proteins, Xenograft Model Antitumor Assays
Added February 15, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection.
Lawson WE, Crossno PF, Polosukhin VV, Roldan J, Cheng DS, Lane KB, Blackwell TR, Xu C, Markin C, Ware LB, Miller GG, Loyd JE, Blackwell TS
(2008) Am J Physiol Lung Cell Mol Physiol 294: L1119-26
MeSH Terms: Antigens, Viral, Cells, Cultured, DNA-Binding Proteins, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Glycoproteins, Heat-Shock Proteins, Herpesviridae Infections, Humans, Immunohistochemistry, Molecular Chaperones, Nuclear Proteins, Protein Folding, Pulmonary Alveoli, Pulmonary Fibrosis, Pulmonary Surfactant-Associated Protein C, Regulatory Factor X Transcription Factors, Stress, Physiological, Transcription Factors, alpha-Mannosidase
Added March 5, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Proteasome function is required to maintain muscle cellular architecture.
Haas KF, Woodruff E, Broadie K
(2007) Biol Cell 99: 615-26
MeSH Terms: Animals, Animals, Genetically Modified, Cell Membrane, Cell Nucleus, Cytoplasm, Drosophila Proteins, Drosophila melanogaster, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Larva, Models, Genetic, Molecular Chaperones, Neuromuscular Junction, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Protein Subunits, Sarcomeres, Ubiquitin
Added February 12, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL
(2000) Mol Cell 6: 1355-64
MeSH Terms: Activating Transcription Factor 6, Amino Acid Motifs, Amino Acid Sequence, Animals, CCAAT-Enhancer-Binding Proteins, Carrier Proteins, Cell Line, DNA-Binding Proteins, Endopeptidases, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Humans, Immunoblotting, Intracellular Membranes, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Molecular Chaperones, Molecular Sequence Data, Mutation, Proprotein Convertases, Protein Binding, Protein Processing, Post-Translational, RNA, Messenger, Sequence Alignment, Serine Endopeptidases, Sterol Regulatory Element Binding Protein 1, Thapsigargin, Transcription Factors, Transcription, Genetic, Tunicamycin
Added March 5, 2014
0 Communities
1 Members
0 Resources
31 MeSH Terms