Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 9 of 9

Publication Record

Connections

Activation of lysosomal enzymes in polymorphonuclear leukocytic granules: the role of phospholipid-protein interaction.
Hawiger J, Hawiger A, Koenig MG
(1972) Yale J Biol Med 45: 42-8
MeSH Terms: Acid Phosphatase, Animals, Cell-Free System, Cytoplasmic Granules, Electrophoresis, Disc, Enzyme Activation, Glucuronidase, Hexosaminidases, Leukocytes, Lysosomes, Membranes, Artificial, Models, Biological, Muramidase, Peroxidases, Phospholipids, Phosphorus, Protein Binding, Proteins, Rabbits
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Effect of ligands on alkaline denaturation of fetal hemoglobin and isolated gamma subunits.
Painter TD, Waterman MR
(1973) Biochem Biophys Res Commun 55: 812-7
MeSH Terms: Carboxyhemoglobin, Chromatography, Ion Exchange, Electrophoresis, Disc, Female, Fetal Hemoglobin, Humans, Hydrogen-Ion Concentration, Iron, Kinetics, Ligands, Mercuribenzoates, Methemoglobin, Peptides, Pregnancy, Protein Denaturation, Spectrophotometry, Time Factors, Umbilical Cord
Added February 12, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Complement-dependent platelet injury by staphylococcal protein A.
Hawiger J, Marney SR, Colley DG, Des Prez RM
(1972) J Exp Med 136: 68-80
MeSH Terms: Animals, Antigen-Antibody Complex, Bacterial Proteins, Blood Platelets, Chromatography, Ion Exchange, Complement System Proteins, Electrophoresis, Disc, Immunodiffusion, Immunoglobulin G, In Vitro Techniques, Inflammation, Plasma, Rabbits, Serotonin, Staphylococcal Infections, Staphylococcus, Thromboembolism
Show Abstract · Added December 10, 2013
A new example of complement-mediated platelet injury has been described. Staphylococcal protein A (SPA) causes rabbit platelet injury as manifested by release of platelet 5-hydroxytryptamine (5HT). This reaction is complement-dependent and occurs over a very small range of SPA concentration, larger amounts being inhibitory. Complement fixation by SPA demonstrates the same narrow SPA concentration requirement whereas precipitation of IgG by SPA is roughly proportional to SPA concentration over a wide concentration range. The reaction can be separated into a sensitization step which requires SPA and plasma but not complement, and a release step which does require complement. Complement-mediated platelet damage induced by SPA is a new biologic property of this common component of the cell wall of pathogenic staphylococci which may contribute to the development of inflammatory and thromboembolic reactions complicating intravascular staphylococcal infection.
0 Communities
1 Members
0 Resources
17 MeSH Terms
Role of cysteine residues in hemoglobin structure and function: transfer of p-mercuribenzoate from alpha subunits to beta subunits during tetramer formation.
Waterman MR
(1974) Biochim Biophys Acta 371: 159-67
MeSH Terms: Carbon Radioisotopes, Cysteine, Electrophoresis, Disc, Emulsions, Hemoglobins, Humans, Macromolecular Substances, Mercuribenzoates, Oxygen, Protein Binding, Protein Conformation, Sulfhydryl Compounds, Ultracentrifugation
Added February 12, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
The gelation of deoxyhemoglobin S in erythrocytes as detected by transverse water proton relazation measurements.
Cottam GL, Valentine KM, Yamaoka K, Waterman MR
(1974) Arch Biochem Biophys 162: 487-92
MeSH Terms: Anemia, Sickle Cell, Electrophoresis, Disc, Erythrocytes, Gels, Hemoglobin C, Hemoglobins, Abnormal, Humans, Kinetics, Magnetic Resonance Spectroscopy, Oxyhemoglobins, Temperature, Time Factors, Water
Added February 12, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Physical and chemical properties of opossum hemoglobin. A hemoglobin containing glutamine at position 58 (E7) in the alpha subunit.
Waterman MR, Stenzel P
(1974) Biochim Biophys Acta 359: 401-10
MeSH Terms: Amino Acid Sequence, Amino Acids, Animals, Binding Sites, Boston, Drug Stability, Electron Spin Resonance Spectroscopy, Electrophoresis, Disc, Ferricyanides, Glutamine, Hemoglobins, Hemoglobins, Abnormal, Humans, Mercuribenzoates, Molecular Weight, Opossums, Oxygen, Oxyhemoglobins, Protein Binding, Protein Conformation, Protein Denaturation, Species Specificity, Spectrophotometry, Spectrophotometry, Ultraviolet, Sulfhydryl Compounds, Temperature
Added February 12, 2015
0 Communities
1 Members
0 Resources
26 MeSH Terms
Spin-label studies at F9(93)beta of deoxyhemoglobin S aggregation.
Yamaoka K, Cottam GL, Waterman MR
(1974) Biochem Biophys Res Commun 58: 1058-65
MeSH Terms: Acetamides, Anemia, Sickle Cell, Chromatography, Gel, Cysteine, Electron Spin Resonance Spectroscopy, Electrophoresis, Disc, Hemoglobins, Hemoglobins, Abnormal, Humans, Iodoacetates, Macromolecular Substances, Mercuribenzoates, Oxyhemoglobins, Protein Binding, Protein Conformation, Pyrrolidines, Spin Labels, Temperature, Viscosity
Added February 12, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Kynurenine formamidase. Purification and characterization of the adult chicken liver enzyme and immunochemical analyses of the enzyme of developing chicks.
Bailey CG, Wagner C
(1974) J Biol Chem 249: 4439-44
MeSH Terms: Age Factors, Aminohydrolases, Ammonium Sulfate, Animals, Arylformamidase, Centrifugation, Chick Embryo, Chickens, Chromatography, DEAE-Cellulose, Chromatography, Gel, Electrophoresis, Disc, Female, Hot Temperature, Hydrogen-Ion Concentration, Immunodiffusion, Liver, Molecular Weight, Precipitin Tests, Rabbits, Structure-Activity Relationship
Added January 20, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Effect of carbamidomethylation of cysteine residues G11(104)alpha on the properties of hemoglobin A.
Waterman MR
(1976) Biochim Biophys Acta 439: 167-74
MeSH Terms: Binding Sites, Cysteine, Electron Spin Resonance Spectroscopy, Electrophoresis, Disc, Hemoglobins, Humans, Iodoacetamide, Macromolecular Substances, Oxygen, Oxyhemoglobins, Protein Binding, Protein Conformation
Show Abstract · Added February 12, 2015
A modified hemoglobin tetramer has been prepared containing carbamidomethylated G11(104)alpha cysteine residues. The molecule is electrophoretically identical to hemoglobin A, at pH 8.6, contains 2 titratable sulfhydryl groups per tetramer, and shows a normal oxygen affinity at half-saturation. However, the cooperative oxygen binding is significantly decreased. As the G11(104)alpha cysteine residues are located at the alpha1beta1 contact point in the hemoglobin tetramer, the results of this study indicate that modification within this portion of the molecule does not interfere with the assembly of subunits to form a tetramer or the resultant p50 but can cause a significant alteration of cooperative oxygen binding. In addition, spin-labels attached to this cysteine residue are not sensitive to changes in conformation which may take place at this contact point during oxygen binding. It is therefore possible that modification of the G11(104)alpha cysteine residue abolishes the contribution of the alpha1beta1 contact point to the cooperative oxygen binding phenomenon.
0 Communities
1 Members
0 Resources
12 MeSH Terms