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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes.
Koh DI, Han D, Ryu H, Choi WI, Jeon BN, Kim MK, Kim Y, Kim JY, Parry L, Clarke AR, Reynolds AB, Hur MW
(2014) Proc Natl Acad Sci U S A 111: 15078-83
MeSH Terms: Acetylation, Animals, Apoptosis, Cell Cycle, Cell Line, Cell Proliferation, Cyclin-Dependent Kinase Inhibitor p21, DNA, DNA Damage, DNA Methylation, E1A-Associated p300 Protein, Female, Fibroblasts, HCT116 Cells, HEK293 Cells, Humans, Mice, Mice, Inbred C57BL, Mice, Knockout, Promoter Regions, Genetic, Protein Binding, Response Elements, Transcription Factors, Tumor Suppressor Protein p53
Added May 2, 2016
1 Communities
1 Members
0 Resources
24 MeSH Terms
Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK
(2013) PLoS One 8: e82684
MeSH Terms: Animals, Blood Cells, CREB-Binding Protein, Cells, Cultured, E1A-Associated p300 Protein, Epistasis, Genetic, Hematopoiesis, Mice, Mice, Knockout, Protein Structure, Tertiary, Proto-Oncogene Proteins c-myb
Added March 20, 2014
1 Communities
1 Members
0 Resources
11 MeSH Terms
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.
Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK
(2012) Nat Genet 44: 1104-10
MeSH Terms: Amino Acid Substitution, Animals, CREB-Binding Protein, Cell Line, Tumor, DNA Copy Number Variations, DNA Mutational Analysis, E1A-Associated p300 Protein, Gene Expression Profiling, Gene Regulatory Networks, Genome, Human, Genome-Wide Association Study, Histone-Lysine N-Methyltransferase, Humans, Intercellular Signaling Peptides and Proteins, Lung Neoplasms, Mice, Mice, Knockout, Models, Molecular, Mutation, Myeloid-Lymphoid Leukemia Protein, Nerve Tissue Proteins, Oligonucleotide Array Sequence Analysis, PTEN Phosphohydrolase, Polymorphism, Single Nucleotide, Protein Processing, Post-Translational, Retinoblastoma Protein, Small Cell Lung Carcinoma, Tumor Suppressor Protein p53
Added September 3, 2013
0 Communities
2 Members
0 Resources
28 MeSH Terms
The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300.
Wang XL, Herzog B, Waltner-Law M, Hall RK, Shiota M, Granner DK
(2004) J Biol Chem 279: 34191-200
MeSH Terms: Animals, Antineoplastic Agents, Hormonal, Blotting, Western, Carcinoma, Hepatocellular, Cell Line, Cell Line, Tumor, Chromatin, Dexamethasone, Drug Synergism, E1A-Associated p300 Protein, Gene Expression Regulation, Enzymologic, Genes, Reporter, Glucocorticoids, Hepatocytes, Humans, Ligands, Liver, Liver Neoplasms, Luciferases, Mutation, Nuclear Proteins, Phosphoenolpyruvate Carboxykinase (ATP), Plasmids, Precipitin Tests, Promoter Regions, Genetic, Protein Structure, Tertiary, RNA Polymerase II, Rats, Reverse Transcriptase Polymerase Chain Reaction, Trans-Activators, Transfection, Tretinoin
Added December 10, 2013
0 Communities
1 Members
0 Resources
32 MeSH Terms
Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.
Qiu Y, Guo M, Huang S, Stein R
(2002) Mol Cell Biol 22: 412-20
MeSH Terms: Adenovirus E1A Proteins, Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Line, DNA-Binding Proteins, E1A-Associated p300 Protein, Enhancer Elements, Genetic, Gene Expression Regulation, HeLa Cells, Homeodomain Proteins, Humans, Insulin, Islets of Langerhans, Macromolecular Substances, Mastadenovirus, Nuclear Proteins, Rats, TCF Transcription Factors, Trans-Activators, Transcription Factor 7-Like 1 Protein, Transcription Factors, Transcription, Genetic, Transfection
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain.
de Caestecker MP, Yahata T, Wang D, Parks WT, Huang S, Hill CS, Shioda T, Roberts AB, Lechleider RJ
(2000) J Biol Chem 275: 2115-22
MeSH Terms: Amino Acid Sequence, Animals, COS Cells, Cell Line, Cytoplasm, DNA-Binding Proteins, E1A-Associated p300 Protein, Fluorescent Antibody Technique, Humans, Mice, Molecular Sequence Data, Nuclear Proteins, Precipitin Tests, Proline, Protein Binding, Protein Structure, Tertiary, Smad2 Protein, Smad4 Protein, Trans-Activators, Transcription, Genetic, Transcriptional Activation
Added January 5, 2011
2 Communities
1 Members
0 Resources
21 MeSH Terms
p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein.
Huang S, Qiu Y, Stein RW, Brandt SJ
(1999) Oncogene 18: 4958-67
MeSH Terms: 3T3 Cells, Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, DNA, DNA-Binding Proteins, Dimerization, Dimethyl Sulfoxide, E1A-Associated p300 Protein, Humans, Mice, Nuclear Proteins, Precipitin Tests, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins, Recombinant Fusion Proteins, Response Elements, Sequence Deletion, T-Cell Acute Lymphocytic Leukemia Protein 1, Trans-Activators, Transcription Factors, Transcriptional Activation, Tumor Cells, Cultured
Added December 10, 2013
0 Communities
2 Members
0 Resources
24 MeSH Terms
Requirement of an E1A-sensitive coactivator for long-range transactivation by the beta-globin locus control region.
Forsberg EC, Johnson K, Zaboikina TN, Mosser EA, Bresnick EH
(1999) J Biol Chem 274: 26850-9
MeSH Terms: Acetyltransferases, Adenovirus E1A Proteins, Animals, DNA-Binding Proteins, E1A-Associated p300 Protein, Erythroid-Specific DNA-Binding Factors, Globins, Histone Acetyltransferases, Humans, Leukemia, Erythroblastic, Acute, Locus Control Region, Mice, NF-E2 Transcription Factor, NF-E2 Transcription Factor, p45 Subunit, Nuclear Proteins, Polymerase Chain Reaction, Saccharomyces cerevisiae Proteins, Trans-Activators, Transcription Factors, Transcriptional Activation, Tumor Cells, Cultured
Added June 15, 2010
0 Communities
1 Members
0 Resources
21 MeSH Terms