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Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis.
Renard HF, Simunovic M, Lemière J, Boucrot E, Garcia-Castillo MD, Arumugam S, Chambon V, Lamaze C, Wunder C, Kenworthy AK, Schmidt AA, McMahon HT, Sykes C, Bassereau P, Johannes L
(2015) Nature 517: 493-6
MeSH Terms: Actins, Acyltransferases, Animals, Cell Line, Cell Membrane, Cholera Toxin, Clathrin, Dynamins, Endocytosis, Humans, Rats, Shiga Toxin
Added January 21, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
Bajpai P, Sangar MC, Singh S, Tang W, Bansal S, Chowdhury G, Cheng Q, Fang JK, Martin MV, Guengerich FP, Avadhani NG
(2013) J Biol Chem 288: 4436-51
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Adrenergic alpha-Antagonists, Animals, Cell Line, Cytochrome P-450 CYP2D6, Dopamine Agents, Dopaminergic Neurons, Dynamins, Humans, Mice, Mitochondria, Mitochondrial Proteins, Parkinsonian Disorders, Quinidine, Reactive Oxygen Species, Ubiquitin-Protein Ligases
Added March 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.
Brooks C, Cho SG, Wang CY, Yang T, Dong Z
(2011) Am J Physiol Cell Physiol 300: C447-55
MeSH Terms: Animals, Apoptosis, Apoptosis Regulatory Proteins, Cell Line, Cells, Cultured, Dynamins, Enzyme Activation, GTP Phosphohydrolases, Gene Knockdown Techniques, HeLa Cells, Humans, Membrane Fusion, Membrane Transport Proteins, Mice, Mice, Knockout, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Diseases, Mitochondrial Membrane Transport Proteins, Mitochondrial Proteins, RNA Interference, Rats, Stress, Physiological, bcl-2-Associated X Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
Drosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin.
Vijayakrishnan N, Phillips SE, Broadie K
(2010) Traffic 11: 1567-78
MeSH Terms: Animals, Carboxylic Ester Hydrolases, Catalytic Domain, Drosophila Proteins, Drosophila melanogaster, Dynamins, Endocytosis, Female, Genes, Lethal, Lipase, Male, Protein Structure, Tertiary, Synapses
Added March 29, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells.
Kaddour-Djebbar I, Choudhary V, Brooks C, Ghazaly T, Lakshmikanthan V, Dong Z, Kumar MV
(2010) Int J Oncol 36: 1437-44
MeSH Terms: Apoptosis, Blotting, Western, Calcium, Cell Line, Tumor, Clonazepam, Dynamins, GTP Phosphohydrolases, Humans, Immunohistochemistry, Immunoprecipitation, Male, Membrane Proteins, Microscopy, Electron, Transmission, Microtubule-Associated Proteins, Mitochondria, Mitochondrial Proteins, Prostatic Neoplasms, Sodium-Calcium Exchanger, TNF-Related Apoptosis-Inducing Ligand, Thiazepines, Transfection, bcl-2 Homologous Antagonist-Killer Protein
Added September 12, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Internalization and intracellular trafficking of a PTD-conjugated anti-fibrotic peptide, AZX100, in human dermal keloid fibroblasts.
Flynn CR, Cheung-Flynn J, Smoke CC, Lowry D, Roberson R, Sheller MR, Brophy CM
(2010) J Pharm Sci 99: 3100-21
MeSH Terms: Actins, Amino Acid Sequence, Caveolae, Dermis, Dynamins, Fibroblasts, Heat-Shock Proteins, Small, Humans, Molecular Sequence Data, Peptides, Phosphoproteins, Protein Transport, Up-Regulation, rab GTP-Binding Proteins
Added December 10, 2013
0 Communities
2 Members
0 Resources
14 MeSH Terms
A differential role for endocytosis in receptor-mediated activation of Nox1.
Miller FJ, Chu X, Stanic B, Tian X, Sharma RV, Davisson RL, Lamb FS
(2010) Antioxid Redox Signal 12: 583-93
MeSH Terms: Activating Transcription Factor 1, Animals, Cells, Cultured, Cytoplasmic Vesicles, Dynamins, Endocytosis, Endosomes, Enzyme Activation, Humans, Isoenzymes, Membrane Microdomains, Mice, Mice, Inbred C57BL, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADPH Oxidases, Oxidation-Reduction, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Reactive Oxygen Species, Signal Transduction, Thrombin, Tumor Necrosis Factor-alpha
Added February 22, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models.
Brooks C, Wei Q, Cho SG, Dong Z
(2009) J Clin Invest 119: 1275-85
MeSH Terms: Adenosine Triphosphate, Animals, Apoptosis, Caspase Inhibitors, Cell Line, Cells, Cultured, Cisplatin, Cytochromes c, Dynamins, Enzyme Inhibitors, GTP Phosphohydrolases, Imaging, Three-Dimensional, Kidney Tubular Necrosis, Acute, Kidney Tubules, Proximal, Male, Mice, Mice, Inbred C57BL, Microtubule-Associated Proteins, Mitochondria, Proto-Oncogene Proteins c-bcl-2, RNA, Small Interfering, Rats, Reperfusion Injury, Sodium Azide
Added September 12, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.
Ghavami S, Kerkhoff C, Chazin WJ, Kadkhoda K, Xiao W, Zuse A, Hashemi M, Eshraghi M, Schulze-Osthoff K, Klonisch T, Los M
(2008) Biochim Biophys Acta 1783: 297-311
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Calgranulin A, Calgranulin B, Cell Death, Cell Line, Tumor, Down-Regulation, Dynamins, Fas-Associated Death Domain Protein, High-Temperature Requirement A Serine Peptidase 2, Humans, Intracellular Signaling Peptides and Proteins, Mice, Mitochondria, Mitochondrial Proteins, Protein Binding, Protein Processing, Post-Translational, Receptor for Advanced Glycation End Products, Receptors, Immunologic, Serine Endopeptidases, Signal Transduction, X-Linked Inhibitor of Apoptosis Protein, bcl-X Protein
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.
Parker M, Roberts R, Enriquez M, Zhao X, Takahashi T, Pat Cerretti D, Daniel T, Chen J
(2004) Biochem Biophys Res Commun 323: 17-23
MeSH Terms: Animals, Biotinylation, Blotting, Western, CHO Cells, Cell Membrane, Cell Separation, Cells, Cultured, Clathrin, Cricetinae, DNA, Complementary, Dynamins, Endocytosis, Ephrin-B1, Flow Cytometry, Genes, Dominant, Genetic Vectors, Humans, Ligands, Microscopy, Confocal, Microscopy, Electron, Mutation, Potassium, Receptors, Eph Family, Signal Transduction, Time Factors, Transfection, Umbilical Veins
Added August 27, 2013
1 Communities
2 Members
0 Resources
27 MeSH Terms