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Results: 1 to 10 of 113

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Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C
(2020) Nat Commun 11: 6397
MeSH Terms: ABO Blood-Group System, Aptamers, Peptide, Blood Coagulation, COVID-19, Drug Delivery Systems, Female, Gene Expression Regulation, Host-Derived Cellular Factors, Host-Pathogen Interactions, Humans, Internet, Male, Middle Aged, Proteins, Quantitative Trait Loci, SARS-CoV-2
Added December 18, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic Autoimmunity.
Haycook CP, Balsamo JA, Glass EB, Williams CH, Hong CC, Major AS, Giorgio TD
(2020) Int J Nanomedicine 15: 1215-1228
MeSH Terms: Animals, Autoimmunity, CD4-Positive T-Lymphocytes, Cytokines, Drug Delivery Systems, Female, Hedgehog Proteins, Immunoglobulin Fragments, Immunologic Factors, Mice, Inbred C57BL, Nanoparticles, Polylactic Acid-Polyglycolic Acid Copolymer, Pyrimidinones, Rheumatic Diseases, T-Lymphocytes, T-Lymphocytes, Helper-Inducer, Thiophenes
Added March 30, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Endosomolytic and Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy.
Wang Y, Xie Y, Kilchrist KV, Li J, Duvall CL, Oupický D
(2020) ACS Appl Mater Interfaces 12: 4308-4322
MeSH Terms: Animals, Breast Neoplasms, Drug Delivery Systems, Endosomes, Female, Genetic Therapy, Humans, Mice, MicroRNAs, Nanoparticles, RNA, Small Interfering, Silicon Dioxide
Added March 19, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Carbon monoxide: An emerging therapy for acute kidney injury.
Yang X, de Caestecker M, Otterbein LE, Wang B
(2020) Med Res Rev 40: 1147-1177
MeSH Terms: Acute Kidney Injury, Animals, Carbon Monoxide, Clinical Trials as Topic, Disease Models, Animal, Drug Delivery Systems, Humans
Added May 10, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Evans BC, Fletcher RB, Kilchrist KV, Dailing EA, Mukalel AJ, Colazo JM, Oliver M, Cheung-Flynn J, Brophy CM, Tierney JW, Isenberg JS, Hankenson KD, Ghimire K, Lander C, Gersbach CA, Duvall CL
(2019) Nat Commun 10: 5012
MeSH Terms: Acrylates, Animals, Anions, Cations, Cell Line, Cells, Cultured, Drug Delivery Systems, Endosomes, HEK293 Cells, Humans, Intracellular Space, MCF-7 Cells, Macromolecular Substances, Mice, NIH 3T3 Cells, Nanoparticles, Peptides, Polymers, RAW 264.7 Cells, Rats, Reproducibility of Results
Added November 7, 2019
0 Communities
3 Members
0 Resources
21 MeSH Terms
Preparation, preliminary pharmacokinetic and brain targeting study of metformin encapsulated W/O/W composite submicron emulsions promoted by borneol.
Hong L, Li X, Bao Y, Duvall CL, Zhang C, Chen W, Peng C
(2019) Eur J Pharm Sci 133: 160-166
MeSH Terms: Animals, Brain, Camphanes, Drug Compounding, Drug Delivery Systems, Drug Liberation, Emulsions, Female, Hypoglycemic Agents, Male, Metformin, Rats, Sprague-Dawley
Added April 10, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.
Kilchrist KV, Dimobi SC, Jackson MA, Evans BC, Werfel TA, Dailing EA, Bedingfield SK, Kelly IB, Duvall CL
(2019) ACS Nano 13: 1136-1152
MeSH Terms: Biological Availability, Biological Products, Drug Carriers, Drug Delivery Systems, Endosomes, Galectins, High-Throughput Screening Assays, Humans
Added April 10, 2019
0 Communities
1 Members
0 Resources
8 MeSH Terms
Platelet-Based Drug Delivery for Cancer Applications.
Ortiz-Otero N, Mohamed Z, King MR
(2018) Adv Exp Med Biol 1092: 235-251
MeSH Terms: Blood Platelets, Drug Delivery Systems, Hemostasis, Humans, Male, Neoplasm Metastasis, Neoplasms
Added April 15, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects.
Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR
(2019) J Biomed Mater Res B Appl Biomater 107: 1491-1503
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Calcium Phosphates, Drug Delivery Systems, Durapatite, Humans, Mandible, Mandibular Injuries, Recombinant Proteins, Swine, Swine, Miniature, Tomography, X-Ray Computed
Added March 20, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Macrophage-Targeted Therapeutics for Metabolic Disease.
Peterson KR, Cottam MA, Kennedy AJ, Hasty AH
(2018) Trends Pharmacol Sci 39: 536-546
MeSH Terms: Drug Delivery Systems, Gene Expression, Humans, Macrophages, Metabolic Diseases, Molecular Targeted Therapy, Pharmaceutical Preparations
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms