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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 838

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Blood metabolomics in infants enrolled in a dose escalation pilot trial of budesonide in surfactant.
Ballard PL, Torgerson D, Wadhawan R, Hudak ML, Weitkamp JH, Harris J, Asselin J, Chapin C, Ballard RA, McEvoy CT
(2021) Pediatr Res 90: 784-794
MeSH Terms: Anti-Inflammatory Agents, Budesonide, Chromatography, Liquid, Dose-Response Relationship, Drug, Dried Blood Spot Testing, Humans, Infant, Infant, Premature, Limit of Detection, Metabolomics, Pilot Projects, Pulmonary Surfactants, Tandem Mass Spectrometry
Added April 16, 2021
0 Communities
1 Members
0 Resources
13 MeSH Terms
N-[F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.
Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H
(2020) Bioorg Med Chem Lett 30: 127257
MeSH Terms: Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Cell Proliferation, Crizotinib, Dose-Response Relationship, Drug, Fluorine Radioisotopes, Humans, Lung Neoplasms, Molecular Imaging, Molecular Structure, Positron-Emission Tomography, Protein Kinase Inhibitors, Structure-Activity Relationship
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Dose-escalation trial of budesonide in surfactant for prevention of bronchopulmonary dysplasia in extremely low gestational age high-risk newborns (SASSIE).
McEvoy CT, Ballard PL, Ward RM, Rower JE, Wadhawan R, Hudak ML, Weitkamp JH, Harris J, Asselin J, Chapin C, Ballard RA
(2020) Pediatr Res 88: 629-636
MeSH Terms: Anti-Inflammatory Agents, Birth Weight, Bronchopulmonary Dysplasia, Budesonide, Cytokines, Dose-Response Relationship, Drug, Female, Humans, Hydrocortisone, Infant, Extremely Premature, Infant, Newborn, Infant, Premature, Male, Risk, Surface-Active Agents, Treatment Outcome
Added April 16, 2021
0 Communities
1 Members
0 Resources
16 MeSH Terms
Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of TcdB-Induced Necrosis.
Farrow MA, Chumber NM, Bloch SC, King M, Moton-Melancon K, Shupe J, Washington MK, Spiller BW, Lacy DB
(2020) ACS Chem Biol 15: 1212-1221
MeSH Terms: Actin Cytoskeleton, Animals, Anti-Infective Agents, Bacterial Toxins, Calcium Channel Blockers, Calcium Channels, Calcium Signaling, Clostridioides difficile, Cytokines, Dihydropyridines, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Glucosyltransferases, Humans, Kinetics, Mice, NADPH Oxidases, Necrosis, Reactive Oxygen Species, Virulence Factors
Added March 24, 2020
0 Communities
2 Members
0 Resources
20 MeSH Terms
An anthrone-based Kv7.2/7.3 channel blocker with improved properties for the investigation of psychiatric and neurodegenerative disorders.
Porter JD, Vivas O, Weaver CD, Alsafran A, DiMilo E, Arnold LA, Dickson EJ, Dockendorff C
(2019) Bioorg Med Chem Lett 29: 126681
MeSH Terms: Anthracenes, Dose-Response Relationship, Drug, KCNQ2 Potassium Channel, KCNQ3 Potassium Channel, Mental Disorders, Molecular Structure, Neurodegenerative Diseases, Potassium Channel Blockers, Structure-Activity Relationship
Added March 27, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.
Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts LJ, Chazin WJ, Davies SS, Skaar EP
(2019) mBio 10:
MeSH Terms: Animals, Anti-Bacterial Agents, Arachidonic Acid, Brain, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Female, Kidney, Lipid Peroxidation, Lipids, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Mutation, Neutrophils, Oxidative Stress, Reactive Oxygen Species, Spleen, Staphylococcal Infections, Staphylococcus aureus, Teichoic Acids
Added March 11, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
Further exploration of an N-aryl phenoxyethoxy pyridinone-based series of mGlu NAMs: Challenging SAR, enantiospecific activity and in vivo efficacy.
Yamada Y, Yohn SE, Gilliland K, Loch MT, Schulte ML, Rodriguez AL, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW
(2019) Bioorg Med Chem Lett 29: 2670-2674
MeSH Terms: Animals, Anti-Anxiety Agents, Antidepressive Agents, Dose-Response Relationship, Drug, Mice, Molecular Structure, Pyridones, Rats, Receptors, Metabotropic Glutamate, Stereoisomerism, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Alcohol Use in Pregnancy and Miscarriage: A Systematic Review and Meta-Analysis.
Sundermann AC, Zhao S, Young CL, Lam L, Jones SH, Velez Edwards DR, Hartmann KE
(2019) Alcohol Clin Exp Res 43: 1606-1616
MeSH Terms: Abortion, Spontaneous, Alcohol Drinking, Dose-Response Relationship, Drug, Female, Humans, Pregnancy
Added August 5, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Effect of environmental salt concentration on the Helicobacter pylori exoproteome.
Caston RR, Loh JT, Voss BJ, McDonald WH, Scholz MB, McClain MS, Cover TL
(2019) J Proteomics 202: 103374
MeSH Terms: Bacterial Proteins, Dose-Response Relationship, Drug, Gene Expression Regulation, Bacterial, Helicobacter pylori, Proteome, Proteomics, Sodium Chloride, Dietary
Added July 14, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation.
Sammons RM, Perry NA, Li Y, Cho EJ, Piserchio A, Zamora-Olivares DP, Ghose R, Kaoud TS, Debevec G, Bartholomeusz C, Gurevich VV, Iverson TM, Giulianotti M, Houghten RA, Dalby KN
(2019) ACS Chem Biol 14: 1183-1194
MeSH Terms: Binding Sites, Crystallography, X-Ray, Dose-Response Relationship, Drug, Enzyme Activation, Guanidine, Humans, Mitogen-Activated Protein Kinase 1, Nuclear Magnetic Resonance, Biomolecular, Phosphorylation, Protein Kinase Inhibitors, Substrate Specificity
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms