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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition.
Albertolle ME, Kim D, Nagy LD, Yun CH, Pozzi A, Savas Ü, Johnson EF, Guengerich FP
(2017) J Biol Chem 292: 11230-11242
MeSH Terms: Animals, Catalysis, Cytochrome P-450 CYP4A, Dithiothreitol, Heme, Humans, Hydrogen Peroxide, Hydroxyeicosatetraenoic Acids, Kidney, Liver, Mice, Mice, Transgenic, Oxidation-Reduction, Rats
Added March 14, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier.
Meredith ME, Qu ZC, May JM
(2014) Biochem Biophys Res Commun 445: 30-5
MeSH Terms: Acetylcysteine, Animals, Antioxidants, Ascorbic Acid, Benzamides, Cell Line, Cell Membrane Permeability, Cells, Cultured, Chromans, Cyclic N-Oxides, Dithiothreitol, Dose-Response Relationship, Drug, Endothelial Cells, Glucose, Glycation End Products, Advanced, HMGB1 Protein, Human Umbilical Vein Endothelial Cells, Humans, Mice, Receptor for Advanced Glycation End Products, Receptors, Immunologic, Serum Albumin, Bovine, Spin Labels
Added May 27, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Etoposide quinone is a redox-dependent topoisomerase II poison.
Jacob DA, Mercer SL, Osheroff N, Deweese JE
(2011) Biochemistry 50: 5660-7
MeSH Terms: Antigens, Neoplasm, Benzoquinones, Catechols, DNA Adducts, DNA Damage, DNA Topoisomerases, Type II, DNA-Binding Proteins, Dithiothreitol, Enzyme Stability, Etoposide, Humans, Leukemia, Myeloid, Acute, Oxidation-Reduction, Reducing Agents
Added March 13, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the alpha1alpha1alpha2 collagen IV network: a role for the post-translational modification of lysine 211 to hydroxylysine 211 in hexamer assembly.
Vanacore RM, Friedman DB, Ham AJ, Sundaramoorthy M, Hudson BG
(2005) J Biol Chem 280: 29300-10
MeSH Terms: Amino Acid Sequence, Animals, Cattle, Collagen Type IV, Cross-Linking Reagents, Crystallography, X-Ray, Dimerization, Dithiothreitol, Hydroxylysine, Lysine, Mass Spectrometry, Methionine, Models, Molecular, Molecular Sequence Data, Placenta, Proline, Protein Binding, Protein Processing, Post-Translational, Protein Structure, Tertiary, Sequence Analysis, Protein, Spectrometry, Mass, Electrospray Ionization, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Trypsin
Added December 10, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
1,4-Benzoquinone is a topoisomerase II poison.
Lindsey RH, Bromberg KD, Felix CA, Osheroff N
(2004) Biochemistry 43: 7563-74
MeSH Terms: Base Sequence, Benzoquinones, Catalysis, Cells, Cultured, DNA Topoisomerases, Type II, DNA, Circular, Dithiothreitol, Glutathione, Humans, Plasmids, Topoisomerase II Inhibitors
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.
Armstrong JS, Steinauer KK, Hornung B, Irish JM, Lecane P, Birrell GW, Peehl DM, Knox SJ
(2002) Cell Death Differ 9: 252-63
MeSH Terms: Antimetabolites, Antineoplastic, Apoptosis, Buthionine Sulfoximine, Cell Cycle, Cytochrome c Group, Cytosol, Dithiothreitol, Glutathione, Humans, Lymphoma, B-Cell, Membrane Potentials, Mitochondria, NF-kappa B, Protein Transport, Reactive Oxygen Species, Signal Transduction, Transcription Factor RelA, Tumor Cells, Cultured, Tumor Suppressor Protein p53
Added February 15, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
Expression of Bcl-2 increases intracellular glutathione by inhibiting methionine-dependent GSH efflux.
Meredith MJ, Cusick CL, Soltaninassab S, Sekhar KS, Lu S, Freeman ML
(1998) Biochem Biophys Res Commun 248: 458-63
MeSH Terms: Culture Media, Cysteine, Dithiothreitol, Glutamate-Cysteine Ligase, Glutathione, HeLa Cells, Humans, Kinetics, Methionine, Proto-Oncogene Proteins c-bcl-2, Recombinant Proteins, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Leukocyte 12-lipoxygenase: expression, purification, and investigation of the role of methionine residues in turnover-dependent inactivation and 5,8,11,14-eicosatetraynoic acid inhibition.
Richards KM, Marnett LJ
(1997) Biochemistry 36: 6692-9
MeSH Terms: Amino Acid Sequence, Ammonium Sulfate, Animals, Arachidonate 12-Lipoxygenase, Catalase, Chemical Precipitation, Chromatography, Ion Exchange, DNA, Complementary, Dithiothreitol, Escherichia coli, Gene Expression, Humans, Leukocytes, Lipoxygenase Inhibitors, Methionine, Molecular Sequence Data, Mutagenesis, Site-Directed, Recombinant Proteins, Sequence Alignment, Structure-Activity Relationship, Swine
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Reductive cleavage of the disulfide bonds of the collagen IV noncollagenous domain in aqueous sodium dodecyl sulfate: absence of intermolecular nondisulfide cross-links.
Reddy GK, Hudson BG, Bailey AJ, Noelken ME
(1993) Biochem Biophys Res Commun 190: 277-82
MeSH Terms: Alkylation, Animals, Aorta, Basement Membrane, Cattle, Chromatography, High Pressure Liquid, Collagen, Cross-Linking Reagents, Disulfides, Dithiothreitol, Electrophoresis, Polyacrylamide Gel, Female, Humans, Hydrolysis, Kidney Glomerulus, Lysine, Macromolecular Substances, Mercaptoethanol, Muscle, Smooth, Vascular, Oxidation-Reduction, Placenta, Pregnancy, Sodium Dodecyl Sulfate
Added December 10, 2013
1 Communities
1 Members
0 Resources
23 MeSH Terms
Localization of the hemagglutinating activity of platelet thrombospondin to a 140 000-dalton thermolytic fragment.
Haverstick DM, Dixit VM, Grant GA, Frazier WA, Santoro SA
(1984) Biochemistry 23: 5597-603
MeSH Terms: Blood Platelets, Calcium, Dithiothreitol, Erythrocytes, Glycoproteins, Hemagglutination, Heparin, Humans, Magnesium, Molecular Weight, Peptide Fragments, Thermolysin, Thrombospondins
Added March 5, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms