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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.
Navarro G, Allard C, Morford JJ, Xu W, Liu S, Molinas AJ, Butcher SM, Fine NH, Blandino-Rosano M, Sure VN, Yu S, Zhang R, Münzberg H, Jacobson DA, Katakam PV, Hodson DJ, Bernal-Mizrachi E, Zsombok A, Mauvais-Jarvis F
(2018) JCI Insight 3:
MeSH Terms: Androgens, Animals, Diabetes Mellitus, Type 2, Diet, Western, Dihydrotestosterone, Female, Glucose, Humans, Hyperinsulinism, Hypothalamus, Insulin Resistance, Insulin-Secreting Cells, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Neurons, Receptors, Androgen, Streptozocin
Added June 28, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6.
Cho DC, Brennan HJ, Johnson RW, Poulton IJ, Gooi JH, Tonkin BA, McGregor NE, Walker EC, Handelsman DJ, Martin TJ, Sims NA
(2017) Nat Commun 8: 806
MeSH Terms: Androgens, Animals, Cancellous Bone, Chondrocytes, Dihydrotestosterone, Estradiol, Female, Interleukin-6, Male, Mice, Inbred C57BL, Osteogenesis, Ovariectomy, Suppressor of Cytokine Signaling 3 Protein
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors.
Lehmann BD, Bauer JA, Schafer JM, Pendleton CS, Tang L, Johnson KC, Chen X, Balko JM, Gómez H, Arteaga CL, Mills GB, Sanders ME, Pietenpol JA
(2014) Breast Cancer Res 16: 406
MeSH Terms: Androgen Receptor Antagonists, Animals, Antineoplastic Agents, Cell Line, Tumor, Cell Survival, Class I Phosphatidylinositol 3-Kinases, Cluster Analysis, Dihydrotestosterone, Disease Models, Animal, Drug Resistance, Neoplasm, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Mutation, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Protein Kinase Inhibitors, Receptors, Androgen, Signal Transduction, TOR Serine-Threonine Kinases, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added January 20, 2015
1 Communities
2 Members
0 Resources
23 MeSH Terms
Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells.
Schultz MA, Hagan SS, Datta A, Zhang Y, Freeman ML, Sikka SC, Abdel-Mageed AB, Mondal D
(2014) PLoS One 9: e87204
MeSH Terms: Analysis of Variance, Cell Line, Tumor, Chromatin Immunoprecipitation, DNA Primers, Dihydrotestosterone, Electrophoretic Mobility Shift Assay, Humans, Immunoblotting, Luciferases, Male, NF-E2-Related Factor 2, Nuclear Respiratory Factor 1, Prostatic Neoplasms, Castration-Resistant, Real-Time Polymerase Chain Reaction, Receptors, Androgen, Transcriptional Activation
Added March 13, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.
Cheng Q, Sohl CD, Yoshimoto FK, Guengerich FP
(2012) J Biol Chem 287: 29554-67
MeSH Terms: Aromatase, Cytochrome P-450 CYP3A, Dihydrotestosterone, Humans, Hydroxylation, Male, Microsomes, Liver, Oxidation-Reduction
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
Moss PE, Lyles BE, Stewart LV
(2010) Exp Cell Res 316: 3478-88
MeSH Terms: Androgen-Binding Protein, Cell Line, Tumor, Cell Proliferation, Cyclin D1, Dihydrotestosterone, Gene Expression, Genes, Reporter, Humans, Hypoglycemic Agents, Male, Mutation, Neoplasms, Hormone-Dependent, PPAR gamma, Prostate-Specific Antigen, Prostatic Neoplasms, RNA, Small Interfering, Receptors, Androgen, Rosiglitazone, Thiazolidinediones, Transfection
Added March 27, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Supraphysiological testosterone enanthate administration prevents bone loss and augments bone strength in gonadectomized male and female rats.
Yarrow JF, Conover CF, Purandare AV, Bhakta AM, Zheng N, Conrad B, Altman MK, Franz SE, Wronski TJ, Borst SE
(2008) Am J Physiol Endocrinol Metab 295: E1213-22
MeSH Terms: Amino Acids, Androgens, Animals, Body Weight, Bone and Bones, Creatinine, Dihydrotestosterone, Estradiol, Female, Femur, Kidney, Male, Muscle, Skeletal, Orchiectomy, Organ Size, Osteocalcin, Osteoporosis, Ovariectomy, Rats, Rats, Inbred F344, Tensile Strength, Testosterone, Tibia
Added September 20, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Androgen receptor-mediated repression of novel target genes.
Prescott J, Jariwala U, Jia L, Cogan JP, Barski A, Pregizer S, Shen HC, Arasheben A, Neilson JJ, Frenkel B, Coetzee GA
(2007) Prostate 67: 1371-83
MeSH Terms: Androgen Antagonists, Anilides, Cell Line, Tumor, Cycloheximide, Dihydrotestosterone, Gene Expression Regulation, Neoplastic, Humans, Male, Nitriles, Prostatic Neoplasms, Protein Synthesis Inhibitors, RNA, Messenger, RNA, Small Interfering, Receptor, Muscarinic M1, Receptors, Androgen, Receptors, Muscarinic, Reverse Transcriptase Polymerase Chain Reaction, Tosyl Compounds, Transfection
Added September 23, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Identification of novel androgen receptor target genes in prostate cancer.
Jariwala U, Prescott J, Jia L, Barski A, Pregizer S, Cogan JP, Arasheben A, Tilley WD, Scher HI, Gerald WL, Buchanan G, Coetzee GA, Frenkel B
(2007) Mol Cancer 6: 39
MeSH Terms: Adenocarcinoma, Androgens, Binding Sites, Cell Adhesion Molecules, Cell Line, Tumor, Chromosomes, Human, Dihydrotestosterone, Extracellular Matrix Proteins, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Glutathione Transferase, Humans, Intracellular Signaling Peptides and Proteins, Male, Mucin-6, Mucins, Neoplasm Proteins, Neoplasms, Hormone-Dependent, Nuclear Proteins, Oligonucleotide Array Sequence Analysis, Ornithine-Oxo-Acid Transaminase, Prostatic Neoplasms, Protein Kinase C-delta, Pyrroline Carboxylate Reductases, Receptors, Androgen, TRPV Cation Channels, Transcription, Genetic
Added September 23, 2013
0 Communities
1 Members
0 Resources
27 MeSH Terms
Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms.
Jia L, Kim J, Shen H, Clark PE, Tilley WD, Coetzee GA
(2003) Mol Cancer Res 1: 385-92
MeSH Terms: Acetylation, Adenylyl Cyclases, Cell Division, Colforsin, Dihydrotestosterone, Genes, Reporter, Histones, Humans, Interleukin-6, Ligands, Luciferases, Male, Promoter Regions, Genetic, Prostate-Specific Antigen, Prostatic Neoplasms, Receptors, Androgen, Tumor Cells, Cultured
Added May 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms