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Results: 1 to 10 of 130

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T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
Bonami RH, Nyhoff LE, McNitt DH, Hulbert C, Felton JL, Kendall PL, Thomas JW
(2020) J Immunol 205: 3263-3276
MeSH Terms: Animals, Autoantibodies, B-Lymphocytes, Cell Communication, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Mice, Mice, Inbred NOD, Mice, Transgenic, Signaling Lymphocytic Activation Molecule Associated Protein, Th1 Cells
Added December 1, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms
Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function.
Ding Q, Tan ALM, Parra EJ, Cruz M, Sim X, Teo YY, Long J, Alsafar H, Petretto E, Tai ES, Chen H
(2020) J Hum Genet 65: 411-420
MeSH Terms: Animals, Asian Continental Ancestry Group, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Genetic Predisposition to Disease, Genome-Wide Association Study, Guanine Nucleotide Dissociation Inhibitors, Humans, Mice, Muscle, Skeletal, Polymorphism, Single Nucleotide
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health.
Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R
(2020) Diabetes 69: 342-354
MeSH Terms: Acinar Cells, Adolescent, Adult, Age Factors, Aged, Animals, Child, Child, Preschool, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Embryonic Stem Cells, Female, Glucagon-Secreting Cells, Humans, Infant, Insulin-Secreting Cells, Islets of Langerhans, Islets of Langerhans Transplantation, Lipid Droplets, Male, Mice, Microscopy, Electron, Microscopy, Fluorescence, Middle Aged, Rats, Tissue Donors, Young Adult
Added March 29, 2020
0 Communities
1 Members
0 Resources
27 MeSH Terms
Long-term outcomes in mouse models of ischemia-reperfusion-induced acute kidney injury.
Scarfe L, Menshikh A, Newton E, Zhu Y, Delgado R, Finney C, de Caestecker MP
(2019) Am J Physiol Renal Physiol 317: F1068-F1080
MeSH Terms: Acute Kidney Injury, Animals, Diabetes Mellitus, Experimental, Diabetic Nephropathies, Disease Models, Animal, Female, Fibrosis, Kidney Function Tests, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred DBA, Nephrectomy, Reperfusion Injury, Sex Characteristics, Species Specificity
Added May 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice.
Brandt SL, Wang S, Dejani NN, Klopfenstein N, Winfree S, Filgueiras L, McCarthy BP, Territo PR, Serezani CH
(2018) JCI Insight 3:
MeSH Terms: Abscess, Animals, Bacterial Load, Cell Movement, Chemokines, Cytokines, Diabetes Mellitus, Experimental, Female, Inflammation, Leukotriene B4, Macrophages, Male, Methicillin-Resistant Staphylococcus aureus, Mice, Mice, Inbred C57BL, Mice, Knockout, Neutrophils, Receptors, Leukotriene B4, Signal Transduction, Skin, Staphylococcal Skin Infections
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis.
Chhabra P, Spano AJ, Bowers D, Ren T, Moore DJ, Timko MP, Wu M, Brayman KL
(2018) Ann Surg 268: 541-549
MeSH Terms: Animals, Cecum, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Female, Gastrointestinal Microbiome, Homeostasis, Humans, Immunoglobulin M, Mice, Mice, Inbred NOD
Added July 12, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
A specific phosphorylation regulates the protective role of αA-crystallin in diabetes.
Ruebsam A, Dulle JE, Myers AM, Sakrikar D, Green KM, Khan NW, Schey K, Fort PE
(2018) JCI Insight 3:
MeSH Terms: Aged, Animals, Cell Line, Crystallins, Diabetes Mellitus, Experimental, Diabetic Retinopathy, Electroretinography, Ependymoglial Cells, Female, Humans, Male, Mice, Mice, Knockout, Neurons, Phosphorylation, Rats, Rats, Sprague-Dawley, Recombinant Proteins, Retina, Streptozocin, Transfection, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added April 3, 2018
0 Communities
1 Members
0 Resources
23 MeSH Terms
Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes.
Osipovich AB, Magnuson MA
(2018) Cell Stem Cell 22: 12-13
MeSH Terms: Animals, Cellular Reprogramming, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Homeodomain Proteins, Insulin, Insulin-Secreting Cells, Mice, Pancreatic Ducts
Added January 8, 2018
1 Communities
2 Members
0 Resources
9 MeSH Terms
Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.
Clayton HW, Osipovich AB, Stancill JS, Schneider JD, Vianna PG, Shanks CM, Yuan W, Gu G, Manduchi E, Stoeckert CJ, Magnuson MA
(2016) Cell Rep 17: 2028-2041
MeSH Terms: Acinar Cells, Adenoviridae, Alleles, Animals, Cellular Reprogramming, Diabetes Mellitus, Experimental, Doxycycline, Gene Expression Profiling, Homeodomain Proteins, Immunity, Inflammation, Insulin-Secreting Cells, Macrophages, Metaplasia, Mice, Transgenic, Organ Size, Pancreas, Pancreatic Ducts, Reproducibility of Results, Transcription Factors, Transgenes
Added November 18, 2016
3 Communities
3 Members
2 Resources
21 MeSH Terms
Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
Wang X, Yao B, Wang Y, Fan X, Wang S, Niu A, Yang H, Fogo A, Zhang MZ, Harris RC
(2017) Diabetes 66: 494-504
MeSH Terms: Albuminuria, Animals, Cells, Cultured, Cyclooxygenase 2, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Diabetic Nephropathies, Fibrosis, Immunoblotting, Immunohistochemistry, Kidney, Macrophages, Male, Mice, Mice, Knockout, NF-kappa B, Neutrophil Infiltration, Neutrophils, Nitric Oxide Synthase Type II, Real-Time Polymerase Chain Reaction, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP4 Subtype, Signal Transduction, T-Lymphocytes
Added April 26, 2017
1 Communities
1 Members
0 Resources
24 MeSH Terms