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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 72

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Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms.
Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE
(2019) J Infect Dis 219: 1264-1273
MeSH Terms: Animals, Antibodies, Monoclonal, Antigens, Bacterial, Bacterial Proteins, Disease Models, Animal, Female, Hemeproteins, Humans, Hydrogen Deuterium Exchange-Mass Spectrometry, Mice, Mice, Inbred BALB C, Receptors, Cell Surface, Staphylococcal Infections, Staphylococcus aureus
Added March 31, 2019
0 Communities
3 Members
0 Resources
14 MeSH Terms
Mono(2-ethylhexyl) phthalate (MEHP) and mono(2-ethyl-5-oxohexyl) phthalate (MEOHP) but not di(2-ethylhexyl) phthalate (DEHP) bind productively to the peroxisome proliferator-activated receptor ╬│.
Kratochvil I, Hofmann T, Rother S, Schlichting R, Moretti R, Scharnweber D, Hintze V, Escher BI, Meiler J, Kalkhof S, von Bergen M
(2019) Rapid Commun Mass Spectrom 33 Suppl 1: 75-85
MeSH Terms: Cell Line, Cell Survival, Humans, Hydrogen Deuterium Exchange-Mass Spectrometry, Molecular Docking Simulation, PPAR gamma, Phthalic Acids, Protein Binding
Added March 21, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions.
Guengerich FP
(2017) Methods Enzymol 596: 217-238
MeSH Terms: Biocatalysis, Cytochrome P-450 Enzyme System, Deuterium, Enzyme Assays, Humans, Hydrogen Bonding, Kinetics, Models, Chemical, Oxidation-Reduction, Substrate Specificity
Added March 14, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface.
Lim XX, Chandramohan A, Lim XE, Crowe JE, Lok SM, Anand GS
(2017) Structure 25: 1391-1402.e3
MeSH Terms: Antibodies, Neutralizing, Antibodies, Viral, Binding Sites, Antibody, Dengue Virus, Deuterium Exchange Measurement, Epitope Mapping, Epitopes, Humans, Mass Spectrometry, Models, Molecular, Protein Binding, Protein Conformation, Temperature, Viral Envelope Proteins
Added March 14, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds.
Mast N, Anderson KW, Johnson KM, Phan TTN, Guengerich FP, Pikuleva IA
(2017) J Biol Chem 292: 12934-12946
MeSH Terms: Acetylcholine, Alkynes, Allosteric Regulation, Amino Acid Substitution, Anti-HIV Agents, Aspartic Acid, Benzoxazines, Binding Sites, Biocatalysis, Cholesterol 24-Hydroxylase, Cyclopropanes, Deuterium Exchange Measurement, Enzyme Activation, Glutamic Acid, Ligands, Models, Molecular, Molecular Docking Simulation, Mutagenesis, Site-Directed, Mutation, Nerve Tissue Proteins, Peptide Fragments, Protein Conformation, Recombinant Fusion Proteins, gamma-Aminobutyric Acid
Added March 14, 2018
0 Communities
1 Members
0 Resources
24 MeSH Terms
Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia.
Wang C, Pallan PS, Zhang W, Lei L, Yoshimoto FK, Waterman MR, Egli M, Guengerich FP
(2017) J Biol Chem 292: 10767-10778
MeSH Terms: Adrenal Hyperplasia, Congenital, Circular Dichroism, Cytochromes b5, Deuterium Exchange Measurement, Enzyme Stability, Hot Temperature, Humans, Mutation, Protein Domains, Spectrophotometry, Ultraviolet, Steroid 21-Hydroxylase
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Mass spectrometry-based microassay of (2)H and (13)C plasma glucose labeling to quantify liver metabolic fluxes in vivo.
Hasenour CM, Wall ML, Ridley DE, Hughey CC, James FD, Wasserman DH, Young JD
(2015) Am J Physiol Endocrinol Metab 309: E191-203
MeSH Terms: Animals, Biological Transport, Blood Glucose, Carbon Isotopes, Citric Acid Cycle, Deuterium, Gas Chromatography-Mass Spectrometry, Glucose, Isotope Labeling, Liver, Liver Glycogen, Male, Mice, Mice, Inbred C57BL
Added May 27, 2015
0 Communities
3 Members
0 Resources
14 MeSH Terms
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME┬ĚPROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE.
Pallan PS, Wang C, Lei L, Yoshimoto FK, Auchus RJ, Waterman MR, Guengerich FP, Egli M
(2015) J Biol Chem 290: 13128-43
MeSH Terms: Amino Acid Sequence, Animals, Binding Sites, Catalysis, Catalytic Domain, Cattle, Crystallography, X-Ray, Deuterium, Humans, Hydroxylation, Kinetics, Molecular Sequence Data, Oxidation-Reduction, Progesterone, Protein Binding, Protein Conformation, Sequence Homology, Amino Acid, Steroid 21-Hydroxylase, Substrate Specificity
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11.
Kim D, Cha GS, Nagy LD, Yun CH, Guengerich FP
(2014) Biochemistry 53: 6161-72
MeSH Terms: Algorithms, Binding, Competitive, Biocatalysis, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System, Cytochromes b5, Deuterium, Electron Transport, Ferric Compounds, Ferrous Compounds, Humans, Hydroxylation, Kinetics, Lauric Acids, Models, Chemical, Models, Molecular, Oxidation-Reduction, Protein Binding, Protein Structure, Tertiary, Substrate Specificity, Tritium
Added January 20, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Synthetic approach for unsaturated precursors for parahydrogen induced polarization of choline and its analogs.
Shchepin RV, Chekmenev EY
(2013) J Labelled Comp Radiopharm 56: 655-62
MeSH Terms: Choline, Contrast Media, Deuterium, Hydrogen, Nitrogen Isotopes
Added February 13, 2015
0 Communities
1 Members
0 Resources
5 MeSH Terms