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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 139

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Targeted Imaging of VCAM-1 mRNA in a Mouse Model of Laser-Induced Choroidal Neovascularization Using Antisense Hairpin-DNA-Functionalized Gold-Nanoparticles.
Uddin MI, Kilburn TC, Yang R, McCollum GW, Wright DW, Penn JS
(2018) Mol Pharm 15: 5514-5520
MeSH Terms: Animals, Biomarkers, Choroid, Choroidal Neovascularization, Disease Models, Animal, Fluorescent Dyes, Gold, Humans, Intravital Microscopy, Lasers, Male, Metal Nanoparticles, Mice, Mice, Inbred C57BL, Molecular Imaging, Molecular Probes, Oligodeoxyribonucleotides, Antisense, Optical Imaging, RNA, Messenger, Vascular Cell Adhesion Molecule-1, Wet Macular Degeneration
Added April 10, 2019
0 Communities
2 Members
0 Resources
21 MeSH Terms
Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Polymerase Bypass of N(6)-Deoxyadenosine Adducts Derived from Epoxide Metabolites of 1,3-Butadiene.
Kotapati S, Wickramaratne S, Esades A, Boldry EJ, Quirk Dorr D, Pence MG, Guengerich FP, Tretyakova NY
(2015) Chem Res Toxicol 28: 1496-507
MeSH Terms: Butadienes, Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Epoxy Compounds, Humans, Kinetics, Oligodeoxyribonucleotides, Spectrometry, Mass, Electrospray Ionization
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Synthesis of G-N2-(CH2)3-N2-G Trimethylene DNA Interstrand Cross-Links.
Gruppi F, Johnson Salyard TL, Rizzo CJ
(2014) Curr Protoc Nucleic Acid Chem 56: 5.14.1-15
MeSH Terms: Cross-Linking Reagents, Oligodeoxyribonucleotides
Added January 7, 2016
0 Communities
1 Members
0 Resources
2 MeSH Terms
Major groove orientation of the (2S)-N(6)-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene.
Kowal EA, Wickramaratne S, Kotapati S, Turo M, Tretyakova N, Stone MP
(2014) Chem Res Toxicol 27: 1675-86
MeSH Terms: Alkylation, Butadienes, DNA, DNA Adducts, Deoxyadenosines, Epoxy Compounds, Humans, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Nucleic Acid Denaturation, Oligodeoxyribonucleotides, Stereoisomerism, Transition Temperature, ras Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequence.
Stavros KM, Hawkins EK, Rizzo CJ, Stone MP
(2014) Nucleic Acids Res 42: 3450-63
MeSH Terms: Aminoquinolines, Base Sequence, Benzimidazoles, DNA, DNA Adducts, Deoxyribonucleases, Type II Site-Specific, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Protons
Added March 10, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Site-specific stabilization of DNA by a tethered major groove amine, 7-aminomethyl-7-deaza-2'-deoxyguanosine.
Szulik MW, Voehler MW, Ganguly M, Gold B, Stone MP
(2013) Biochemistry 52: 7659-68
MeSH Terms: DNA, Kinetics, Models, Molecular, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Nucleic Acid Denaturation, Nucleoside Q, Nucleotide Motifs, Oligodeoxyribonucleotides, Thermodynamics
Added March 7, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues.
Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL
(2012) Biochemistry 51: 9234-44
MeSH Terms: Carbohydrate Conformation, Catalytic Domain, Crystallography, X-Ray, DNA, Archaeal, DNA-Directed DNA Polymerase, Deoxyadenine Nucleotides, Deoxyribonucleotides, Nucleic Acid Conformation, Substrate Specificity, Sulfolobus solfataricus
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.
Gandhi VV, Samuels DC
(2011) PLoS Comput Biol 7: e1002078
MeSH Terms: Computational Biology, Computer Simulation, DNA Replication, DNA, Mitochondrial, Deoxyribonucleosides, Deoxyribonucleotides, Kinetics, Mitochondria
Added December 12, 2013
0 Communities
1 Members
0 Resources
8 MeSH Terms
A review comparing deoxyribonucleoside triphosphate (dNTP) concentrations in the mitochondrial and cytoplasmic compartments of normal and transformed cells.
Gandhi VV, Samuels DC
(2011) Nucleosides Nucleotides Nucleic Acids 30: 317-39
MeSH Terms: Animals, Biological Transport, Cell Transformation, Neoplastic, Cytoplasm, DNA, Mitochondrial, Deoxyribonucleotides, Humans, Mitochondria
Added May 27, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms