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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 104

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The abundant DNA adduct -methyl deoxyguanosine contributes to miscoding during replication by human DNA polymerase η.
Njuma OJ, Su Y, Guengerich FP
(2019) J Biol Chem 294: 10253-10265
MeSH Terms: DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Humans, Molecular Structure
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
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19 MeSH Terms
The Role of Biomarkers of Oxidative Stress in Breast Cancer Risk and Prognosis: A Systematic Review of the Epidemiologic Literature.
Lee JD, Cai Q, Shu XO, Nechuta SJ
(2017) J Womens Health (Larchmt) 26: 467-482
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Adult, Biomarkers, Tumor, Breast Neoplasms, Deoxyguanosine, Female, Humans, Middle Aged, Oxidative Stress, Prognosis, Risk Factors, Survival Analysis
Added May 19, 2017
0 Communities
2 Members
0 Resources
12 MeSH Terms
Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η.
Xue Q, Zhong M, Liu B, Tang Y, Wei Z, Guengerich FP, Zhang H
(2016) Biochimie 121: 161-9
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Catalytic Domain, DNA-Directed DNA Polymerase, Deoxyguanosine, Kinetics, Pyrimidine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.
Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK
(2015) Nucleic Acids Res 43: 8340-51
MeSH Terms: DNA, DNA Adducts, DNA-Directed DNA Polymerase, Deoxyguanosine, HEK293 Cells, Humans, Mutagens, Mutation Rate, Quinolines
Added January 7, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.
Stavros KM, Hawkins EK, Rizzo CJ, Stone MP
(2015) Chem Res Toxicol 28: 1455-68
MeSH Terms: Circular Dichroism, DNA, Deoxyguanosine, Deoxyribonucleases, Type II Site-Specific, Intercalating Agents, Magnetic Resonance Spectroscopy, Molecular Conformation, Nucleic Acid Conformation, Protons, Quinolines, Spectrophotometry, Ultraviolet
Added January 7, 2016
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1 Members
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11 MeSH Terms
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV.
Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M
(2015) J Am Chem Soc 137: 7011-4
MeSH Terms: DNA Damage, DNA-Directed DNA Polymerase, Deoxyguanosine, Models, Molecular, Pyrimidines, Sulfolobus solfataricus
Added January 7, 2016
0 Communities
1 Members
0 Resources
6 MeSH Terms
Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.
Su Y, Patra A, Harp JM, Egli M, Guengerich FP
(2015) J Biol Chem 290: 15921-33
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Amino Acid Motifs, Catalytic Domain, Crystallography, X-Ray, DNA, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Humans, Mutagenesis, Site-Directed, Substrate Specificity
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB.
Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM
(2014) Chem Res Toxicol 27: 1619-31
MeSH Terms: Acrolein, Borohydrides, Chromatography, High Pressure Liquid, DNA, DNA Adducts, DNA Repair, DNA, Single-Stranded, Deoxyguanosine, Escherichia coli Proteins, Malondialdehyde, Mixed Function Oxygenases, Oligonucleotides, Tandem Mass Spectrometry
Added January 7, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine.
Christov PP, Son KJ, Rizzo CJ
(2014) Chem Res Toxicol 27: 1610-8
MeSH Terms: Base Sequence, DNA Adducts, DNA Repair, DNA-Formamidopyrimidine Glycosylase, Deoxyguanosine, Deoxyribonuclease IV (Phage T4-Induced), Electrophoresis, Agar Gel, Escherichia coli, Escherichia coli Proteins, Kinetics, Mechlorethamine, Oligonucleotides, Organophosphorus Compounds, Pyrimidines
Added January 7, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms