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Effect of psychotropic drug treatment on sterol metabolism.
Korade Ž, Liu W, Warren EB, Armstrong K, Porter NA, Konradi C
(2017) Schizophr Res 187: 74-81
MeSH Terms: Adult, Animals, Antidepressive Agents, Antipsychotic Agents, Body Mass Index, Cholestadienols, Clozapine, Dehydrocholesterols, Female, Haloperidol, Humans, Lipid Metabolism, Male, Mental Disorders, Psychiatric Status Rating Scales, Random Allocation, Rats, Sprague-Dawley, Weight Gain
Added April 6, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.
Goyal S, Xiao Y, Porter NA, Xu L, Guengerich FP
(2014) J Lipid Res 55: 1933-43
MeSH Terms: Cholesterol 24-Hydroxylase, Dehydrocholesterols, Desmosterol, Humans, Kinetics, Oxidation-Reduction, Protein Binding, Steroid Hydroxylases
Added January 20, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO.
Björkhem I, Diczfalusy U, Lövgren-Sandblom A, Starck L, Jonsson M, Tallman K, Schirmer H, Ousager LB, Crick PJ, Wang Y, Griffiths WJ, Guengerich FP
(2014) J Lipid Res 55: 1165-72
MeSH Terms: Adolescent, Adult, Child, Cholesterol 7-alpha-Hydroxylase, Dehydrocholesterols, Down-Regulation, Female, Gene Expression Regulation, Enzymologic, Humans, Ketocholesterols, Smith-Lemli-Opitz Syndrome, Xanthomatosis, Cerebrotendinous
Added May 26, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Reactivities and products of free radical oxidation of cholestadienols.
Xu L, Porter NA
(2014) J Am Chem Soc 136: 5443-50
MeSH Terms: Dehydrocholesterols, Free Radicals, Molecular Conformation, Oxidation-Reduction
Added March 20, 2014
0 Communities
1 Members
0 Resources
4 MeSH Terms
A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz syndrome.
Liu W, Xu L, Lamberson C, Haas D, Korade Z, Porter NA
(2014) J Lipid Res 55: 329-37
MeSH Terms: Animals, Blood Chemical Analysis, Cell Line, Tumor, Dehydrocholesterols, Heterozygote, Humans, Mice, Nervous System, Smith-Lemli-Opitz Syndrome, Triazoles
Added March 20, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.
Windsor K, Genaro-Mattos TC, Kim HY, Liu W, Tallman KA, Miyamoto S, Korade Z, Porter NA
(2013) J Lipid Res 54: 2842-50
MeSH Terms: Cell Line, Tumor, Cytochromes c, Dehydrocholesterols, Fatty Acids, Unsaturated, Humans, Lipoylation, Oxidation-Reduction, Phospholipids, Protein Processing, Post-Translational, Proteome, Smith-Lemli-Opitz Syndrome
Added March 7, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
A perspective on free radical autoxidation: the physical organic chemistry of polyunsaturated fatty acid and sterol peroxidation.
Porter NA
(2013) J Org Chem 78: 3511-24
MeSH Terms: Chemistry, Physical, Dehydrocholesterols, Fatty Acids, Unsaturated, Free Radicals, Heterocyclic Oxides, Humans, Oxidative Stress, Peroxides, Sterols
Added March 7, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells.
Xu L, Korade Z, Rosado DA, Mirnics K, Porter NA
(2013) J Lipid Res 54: 1135-43
MeSH Terms: Animals, Cell Line, Cells, Cultured, Chromatography, High Pressure Liquid, Dehydrocholesterols, Fibroblasts, Humans, Lipid Metabolism, Mass Spectrometry, Mice, Mice, Knockout, Oxidation-Reduction, Oxidoreductases Acting on CH-CH Group Donors, Tandem Mass Spectrometry
Added March 7, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patients.
Liu W, Xu L, Lamberson CR, Merkens LS, Steiner RD, Elias ER, Haas D, Porter NA
(2013) J Lipid Res 54: 244-53
MeSH Terms: Adolescent, Adult, Blood Chemical Analysis, Blood Specimen Collection, Child, Child, Preschool, Chromatography, High Pressure Liquid, Dehydrocholesterols, Esters, Female, Humans, Infant, Male, Oxidation-Reduction, Smith-Lemli-Opitz Syndrome, Tandem Mass Spectrometry, Young Adult
Added March 20, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome.
Korade Z, Xu L, Mirnics K, Porter NA
(2013) J Inherit Metab Dis 36: 113-22
MeSH Terms: Animals, Biomarkers, Brain, Dehydrocholesterols, Disease Models, Animal, Lipid Peroxidation, Liver, Mice, Mice, Knockout, Oxidation-Reduction, Oxidative Stress, Smith-Lemli-Opitz Syndrome
Added March 7, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms