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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 9 of 9

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A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1.
Nnamani MC, Ganguly S, Erkenbrack EM, Lynch VJ, Mizoue LS, Tong Y, Darling HL, Fuxreiter M, Meiler J, Wagner GP
(2016) Cell Rep 15: 2097-2108
MeSH Terms: Allosteric Regulation, Amino Acid Sequence, Amino Acid Substitution, Animals, Biological Evolution, CREB-Binding Protein, DNA-Activated Protein Kinase, Forkhead Box Protein O1, HeLa Cells, Homeodomain Proteins, Humans, Intrinsically Disordered Proteins, Mice, Models, Biological, Models, Molecular, Phosphorylation, Protein Binding, Protein Domains, Protein Structure, Secondary, Transcriptional Activation
Added April 8, 2017
1 Communities
1 Members
0 Resources
20 MeSH Terms
Methotrexate inhibits NF-κB activity via long intergenic (noncoding) RNA-p21 induction.
Spurlock CF, Tossberg JT, Matlock BK, Olsen NJ, Aune TM
(2014) Arthritis Rheumatol 66: 2947-57
MeSH Terms: Adult, Antirheumatic Agents, Arthritis, Rheumatoid, Cell Line, Cells, Cultured, Cyclin-Dependent Kinase Inhibitor p21, DNA-Activated Protein Kinase, Dose-Response Relationship, Drug, Female, Humans, Male, Methotrexate, Middle Aged, Monocytes, NF-kappa B, Nuclear Proteins, RNA, Long Noncoding, T-Lymphocytes, Tumor Suppressor Protein p53, eIF-2 Kinase
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
DNA damage response: three levels of DNA repair regulation.
Sirbu BM, Cortez D
(2013) Cold Spring Harb Perspect Biol 5: a012724
MeSH Terms: Ataxia Telangiectasia Mutated Proteins, Chromatin, DNA Damage, DNA Repair, DNA-Activated Protein Kinase, Genomic Instability, Models, Genetic, Phosphorylation
Added March 5, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs.
Lindert S, Stewart PL, Meiler J
(2013) Comput Biol Chem 42: 1-4
MeSH Terms: Algorithms, Catalytic Domain, Computer Simulation, Crystallography, X-Ray, DNA-Activated Protein Kinase, Models, Molecular, Protein Folding
Added January 24, 2015
1 Communities
1 Members
0 Resources
7 MeSH Terms
Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase.
Nam EA, Zhao R, Cortez D
(2011) J Biol Chem 286: 37320-7
MeSH Terms: Amino Acid Substitution, Ataxia Telangiectasia Mutated Proteins, Cell Cycle Proteins, Cell Line, Cell Survival, DNA-Activated Protein Kinase, DNA-Binding Proteins, G2 Phase, Humans, Mutation, Missense, Phosphorylation, Protein Structure, Secondary, Protein-Serine-Threonine Kinases, S Phase, Tumor Suppressor Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Activation of the DNA-dependent protein kinase by drug-induced and radiation-induced DNA strand breaks.
Mårtensson S, Nygren J, Osheroff N, Hammarsten O
(2003) Radiat Res 160: 291-301
MeSH Terms: Aminoglycosides, Anti-Bacterial Agents, Antibiotics, Antineoplastic, Antigens, Nuclear, Antimetabolites, Antineoplastic, Bleomycin, DNA, DNA Damage, DNA Helicases, DNA Repair, DNA Topoisomerases, Type II, DNA-Activated Protein Kinase, DNA-Binding Proteins, Dose-Response Relationship, Drug, Enediynes, Energy Transfer, Enzyme Activation, Etoposide, Ferritins, Ku Autoantigen, Models, Biological, Nucleic Acid Synthesis Inhibitors, Plasmids, Protein Binding, Protein-Serine-Threonine Kinases, Radiation, Ionizing
Added March 5, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Inhibition of cisplatin-induced ATR activity and enhanced sensitivity to cisplatin.
Yazlovitskaya EM, Persons DL
(2003) Anticancer Res 23: 2275-9
MeSH Terms: Adenocarcinoma, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, CDC2 Protein Kinase, Caffeine, Cell Cycle Proteins, Cisplatin, Cyclin B, Cyclin B1, DNA-Activated Protein Kinase, DNA-Binding Proteins, Drug Synergism, Enzyme Induction, Female, Humans, Nuclear Proteins, Ovarian Neoplasms, Phosphorylation, Protein-Serine-Threonine Kinases, Tumor Cells, Cultured, Tumor Suppressor Protein p53, Tumor Suppressor Proteins
Added November 16, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombination.
Smider V, Rathmell WK, Brown G, Lewis S, Chu G
(1998) Mol Cell Biol 18: 6853-8
MeSH Terms: Animals, DNA, DNA Nucleotidyltransferases, DNA-Activated Protein Kinase, DNA-Binding Proteins, Enzyme Activation, Mice, Mice, SCID, Mutation, Nucleic Acid Conformation, Protein-Serine-Threonine Kinases, Recombination, Genetic, VDJ Recombinases
Added October 17, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage.
Rathmell WK, Kaufmann WK, Hurt JC, Byrd LL, Chu G
(1997) Cancer Res 57: 68-74
MeSH Terms: Animals, Animals, Newborn, CCAAT-Enhancer-Binding Proteins, Cricetinae, Cyclin-Dependent Kinase Inhibitor p21, Cyclins, DNA, DNA Damage, DNA-Activated Protein Kinase, DNA-Binding Proteins, Fibroblasts, G1 Phase, G2 Phase, Intracellular Signaling Peptides and Proteins, Mice, Mice, Inbred BALB C, Mice, SCID, Protein-Serine-Threonine Kinases, Proteins, Transcription Factor CHOP, Transcription Factors, Transcription, Genetic, Tumor Suppressor Protein p53
Added October 17, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms